Functional analysis of cyclophilins on feline infectious peritonitis virus replication
Functional analysis of cyclophilins on feline infectious peritonitis virus replication
批准号:
22580343
负责人:
TANAKA Yoshikazu
金额:
$3.0万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010 至 2012
中文摘要
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英文摘要
Feline infectious peritonitis virus (FIPV) causes lethal diseases and no effective vaccine or treatment has been developed. These experiments clarified that Cyclosporin A (CsA) strongly inhibits replication and transcription of FIPV. Also, both cellular cyclophilin A (CypA) and cyclophilin B (CypB), which bind to CsA enhanced the FIPV replication. PPIase activities of Cyp are affected the FIPV replication.
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DOI:
10.3390/v5051250
发表时间:
2013-05-22
期刊:
Viruses
影响因子:
--
作者:
[Tanaka Y, Sato Y, Sasaki T]
通讯作者:
Sasaki T
Population genetic structures of Staphilicoccus aureus isolates from cats and dogs in Japan.
日本猫和狗金黄色葡萄球菌的群体遗传结构。
DOI:
--
发表时间:
2012
期刊:
Journal of Clinical Microbiology.
影响因子:
--
作者:
[Sasaki T, Tsubakishita S, Tanaka Y, Ohtsuka M, Hongo I, Fukata T, Kabeya H, Maruyama S, Hirotaki S, Hiramatsu K.]
通讯作者:
Hiramatsu K.
Peptidylprolyl cis-trans isomerase (PPIase) active sites of cyclophilin are crucial for feline coronavirus replication
亲环蛋白肽基脯氨酰顺反异构酶(PPIase)活性位点对于猫冠状病毒复制至关重要
DOI:
--
发表时间:
2013
期刊:
影响因子:
--
作者:
[釜田佳季, 徳永雄平, 杉元康志, 日下部宜宏, Tanaka Y]
通讯作者:
Tanaka Y
Inhibition of feline infectious peritonitis viral replication by cyclosporine. American Society for Virology meeting
环孢素抑制猫传染性腹膜炎病毒复制。
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[Kuwabara T, Hasegawa D, Ogawa F, Kobayashi M, Fujita M, Suzuki H, Matsuki N, Orima H., Yoshikazu Tanaka]
通讯作者:
Yoshikazu Tanaka
ネコ伝染性腹膜炎ウイルス(FIPV)の予
猫传染性腹膜炎病毒(FIPV)的预测
DOI:
--
发表时间:
2013
期刊:
影响因子:
--
作者:
[]
通讯作者:
共 7 条
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