Determination of the infiltration of neutrophils into organs resulting from repetitive injuries, and development of diagnostic methodsfor the physical abuse

点击翻译按钮获取中文摘要

We investigated neutrophil infiltration into several organs in cases of child and elder physical abuse using immunohistochemistry for myeloperoxidase, a marker for primed neutrophil, P-selectin, anadhesion molecule, and interleukin-8, a chemotactic factor, and indicated that these analyses may represent supportive diagnostic methods for the physical abuse of the child and elderly. We also indicated that infiltrating primed neutrophils released elastase, a cytotoxic mediator, and suggested that patients with physical abuse may be in a primed stage of multiple organ failure.