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A novel method for analyzing inner ear disorders using disease-specific iPS cells

A novel method for analyzing inner ear disorders using disease-specific iPS cells
一种利用疾病特异性 iPS 细胞分析内耳疾病的新方法
批准号:
22591878
负责人:
NAKAGAWA Takayuki
金额:
$2.83万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010 至 2012

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中文摘要
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英文摘要
To utilize disease-specific iPS cells for the development of novel therapeutics for inner ear diseases, methods for otic induction of iPS cell have been developed, which have high efficiency for induction of hair cell-like cells. We also generated iPS cell lines derived from TRIOBP deficiency mice, and examined their potential for hair cell differentiation. For further progress, a method for induction of mature hair bundles should be established.
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内耳再生医学发展与未来听力损失治疗
DOI: --
发表时间: 2013
期刊:
影响因子: --
作者: [Obata K, Kojima T, Yokota S, Tsutsumi H, Himi T. (全15名2, 14番), Nakagawa T, 中川隆之]
通讯作者: 中川隆之
Retention of stem cell phenotypes in long-term culture neonatal mouse otospheres
长期培养的新生小鼠耳球中干细胞表型的保留
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发表时间: 2011
期刊:
影响因子: --
作者: [Xiangxin Lou, Xiangxin Lou]
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发表时间: 2010
期刊:
影响因子: --
作者: [Nishimura K, Yamamoto N, Nakagawa T, Ito J]
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内耳再生へのストラテジー 内耳障害の病態に応じた治療法の開発戦略
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DOI: --
发表时间: 2013
期刊: 日薬理誌
影响因子: --
作者: [Shintaku H, Inaoka T, Nakagawa T, Kawano S, Ito J., 加藤聖子, 中川隆之]
通讯作者: 中川隆之
14
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    • 项目类别:
      Grant-in-Aid for Scientific Research (B)
    • 资助金额:
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    • 财政年份:
      2017
    • 负责人:
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    • 项目类别:
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    • 资助金额:
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    • 财政年份:
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