Research on the role of βadrenergic receptors in pathogenesis of Meniere's disease
Research on the role of βadrenergic receptors in pathogenesis of Meniere's disease
批准号:
22591883
负责人:
MORI Nozomu
金额:
$2.83万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010 至 2012
中文摘要
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英文摘要
The results that catecholamines increased endolymphatic hydropressure in the cochlea and semicircular canalin the normal guinea pigs but not in the guinea pigs with obstructed endolymphatic sac (ES) strongly suggest the involvement of ES in increased endolymphatic hydropressure by catecholamines. The findings that catecholamines increased endolymphatic hydropressure in the cochlea to a larger degree than that in the semicircular canalcorrespond to clinical findings that Meniere patients suffer more frequently from the cochlear symptoms than the vestibular symptoms. The strong expression of β2-adrenergic receptor in epithelial cells of the ES intermediate portion accords with the electrophysiological results that catecholamines decrease ES direct current potentialvia β2-action.
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Laser Capture Microdissection : Methods and Protocols, Methods in Molecular Biology, Vol.755
激光捕获显微切割:方法和方案,分子生物学方法,第 755 卷
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[Akiyama, K., et al]
通讯作者:
et al
DOI:
10.1016/j.anl.2011.11.005
发表时间:
2012-12-01
期刊:
AURIS NASUS LARYNX
影响因子:
1.7
作者:
[Miyashita, Takenori, Toyama, Yoshihiro, Mori, Nozomu]
通讯作者:
Mori, Nozomu
DOI:
10.1016/j.anl.2011.07.004
发表时间:
2012-08
期刊:
Auris, nasus, larynx
影响因子:
--
作者:
[Ai Matsubara;T. Miyashita;Terushige Mori;Kosuke Akiyama;Ryuhei Inamoto;Nozomu Mori]
通讯作者:
Ai Matsubara;T. Miyashita;Terushige Mori;Kosuke Akiyama;Ryuhei Inamoto;Nozomu Mori
イソプロテレノールの内耳への影響
异丙肾上腺素对内耳的影响
DOI:
--
发表时间:
期刊:
影响因子:
--
作者:
[Fuchiwaki T, Sun X, Fujimura K, Yamada H, Shibata K, Muta H, Podack ER, Kawauchi H, Yoshikai Y, 淵脇貴史, 淵脇貴史, 淵脇貴史, 淵脇貴史, 稲本 隆平, 稲本 隆平, 稲本 隆平]
通讯作者:
稲本 隆平
Presence of adrenergic receptors in the rat endolymphatic sac epithelial cells.
大鼠内淋巴囊上皮细胞中存在肾上腺素能受体。
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[Matsubara,A., T. Miyashita, T..Inamoto and N. Mori]
通讯作者:
T..Inamoto and N. Mori
共 10 条
Regulatory roles of NRSF/REST variants in the aging brain
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批准号:15K14352
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项目类别:Grant-in-Aid for Challenging Exploratory Research
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资助金额:$2.5万
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财政年份:2015
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负责人:MORI Nozomu
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依托单位:
Establishment of an in vitro aging system of non-dividing cells
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批准号:24650200
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项目类别:Grant-in-Aid for Challenging Exploratory Research
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资助金额:$2.5万
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财政年份:2012
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负责人:MORI Nozomu
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依托单位:
Positive and negative regulations of cytoskeletal dynamism and neuronal lifespan
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批准号:22300121
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$11.65万
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财政年份:2010
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负责人:MORI Nozomu
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依托单位:
Research on the fundamental molecules in relation to controlling brain aging : From neuronal cytoskeleton regulation to neuronal longevity control
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批准号:19300130
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$12.15万
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财政年份:2007
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负责人:MORI Nozomu
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依托单位:
T ranscriptional regulation of neuron-specific genes by neural restrictive silencer
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批准号:14390060
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$8.45万
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财政年份:2002
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负责人:MORI Nozomu
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依托单位:
Research on sodium transport in the endolymphatic sac
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批准号:13671783
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.24万
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财政年份:2001
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负责人:MORI Nozomu
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依托单位:
Molecular biological study of the endolymphatic sac
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批准号:08671969
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$1.47万
-
财政年份:1996
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负责人:MORI Nozomu
-
依托单位:
Electrophysiological and morphological study of endolymphatic sac
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批准号:05454462
-
项目类别:Grant-in-Aid for General Scientific Research (B)
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资助金额:$4.03万
-
财政年份:1993
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负责人:MORI Nozomu
-
依托单位:
Electrophysiological and morphological study of endolymphatic sac
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批准号:02670766
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项目类别:Grant-in-Aid for General Scientific Research (C)
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资助金额:$1.54万
-
财政年份:1990
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负责人:MORI Nozomu
-
依托单位:
海外基金