Induction of autophagic cell death via microRNA-mediated gene regulatory network
Induction of autophagic cell death via microRNA-mediated gene regulatory network
批准号:
22791310
负责人:
TAZAWA Hiroshi
金额:
$2.5万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010 至 2012
中文摘要
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英文摘要
Tumor-specific replication-competent oncolytic adenovirus is a promising antitumor agent. However, the mechanism on the virus-mediated cell death remains unclear. Here we show that telomerase-specific replication-competent oncolytic adenovirus Telomelysin induces autophagic cell death through microRNA-mediated gene regulatory network.
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Oncolytic adenovirus induces autophagic cell death through microRNA-7-mediated suppression of EGFR in human cancer cells.
溶瘤腺病毒通过 microRNA-7 介导的人类癌细胞 EGFR 抑制诱导自噬性细胞死亡。
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[田澤 大, 矢野修也, 吉田亮介, 浦田泰生, 藤原俊義, Hiroshi Tazawa, Hiroshi Tazawa]
通讯作者:
Hiroshi Tazawa
Oncolytic adenovirus inhibits the cancer stem cell properties through microRNA modulation
溶瘤腺病毒通过 microRNA 调节抑制癌症干细胞特性
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[Tazawa H, Onishi T, Yano S, Urata Y, Fujiwara T, Hiroshi Tazawa]
通讯作者:
Hiroshi Tazawa
Oncolytic adenovirus induces autophagic cell death through microRNA-7-mediated suppression of EGFR in human cancer cells
溶瘤腺病毒通过 microRNA-7 介导的人类癌细胞 EGFR 抑制诱导自噬细胞死亡
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[Tazawa H, Yano S, Yoshida R, Urata Y, Fujiwara T]
通讯作者:
Fujiwara T
DOI:
10.1097/sla.0b013e3181deb69d
发表时间:
2010-06-01
期刊:
ANNALS OF SURGERY
影响因子:
9
作者:
[Kojima, Toru, Watanabe, Yuichi, Fujiwara, Toshiyoshi]
通讯作者:
Fujiwara, Toshiyoshi
DOI:
10.1371/journal.pone.0039292
发表时间:
2012
期刊:
PloS one
影响因子:
3.7
作者:
[Hashimoto Y, Tazawa H, Teraishi F, Kojima T, Watanabe Y, Uno F, Yano S, Urata Y, Kagawa S, Fujiwara T]
通讯作者:
Fujiwara T
共 26 条
Experimental treatment of sarcoma by high-intensity focused ultrasound
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批准号:18591622
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.34万
-
财政年份:2006
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负责人:TAZAWA Hiroshi
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依托单位:
Comparative physiological study on environmental temperature effect influencing development of thermoregulatory competence in birds.
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批准号:15560352
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.3万
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财政年份:2003
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负责人:TAZAWA Hiroshi
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依托单位:
Physioengineering approach to the autonomic nervous control of the heart rate fluctuations in developing embryos.
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批准号:08650471
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$1.41万
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财政年份:1996
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负责人:TAZAWA Hiroshi
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依托单位:
Comparative study on respiratory and circulatory functions in avian eggs
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批准号:07044110
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项目类别:Grant-in-Aid for international Scientific Research
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资助金额:$1.92万
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财政年份:1995
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负责人:TAZAWA Hiroshi
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依托单位:
Evaluation of Environmental Amenity for Animals based on Variability of Parameter of Physiological Function.
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批准号:06650448
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项目类别:Grant-in-Aid for General Scientific Research (C)
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资助金额:$0.83万
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财政年份:1994
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负责人:TAZAWA Hiroshi
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依托单位:
Physiological measuring system using chicken eggs as an experimental model animal for physiological functions.
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批准号:03452182
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项目类别:Grant-in-Aid for General Scientific Research (B)
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资助金额:$4.29万
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财政年份:1991
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负责人:TAZAWA Hiroshi
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依托单位:
Physio-Engineering Study on the Cardiac Function of Avian Eggs.
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批准号:01044010
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项目类别:Grant-in-Aid for international Scientific Research
-
资助金额:$2.5万
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财政年份:1989
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负责人:TAZAWA Hiroshi
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依托单位:
A closed-circuit continuous measurement system for metabolic rate and physioengineering study on thermoregulation of chick embryos.
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批准号:62550294
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项目类别:Grant-in-Aid for General Scientific Research (C)
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资助金额:$1.22万
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财政年份:1987
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负责人:TAZAWA Hiroshi
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依托单位:
海外基金