A role of Wnt/beta-catenin signal network on the stimulated bone formation under mechanical stress.

我们可以通过对小鼠颅骨缝合处施加张应力来刺激骨形成。在刺激骨形成过程中，检测了许多因子的基因表达，特别是Wnt/β-catenin家族，其参与骨细胞活性。我们可以显示在实验的每个时间点的一些因素的相对表达率。这些结果表明，在刺激骨形成的每个阶段，哪些因素更重要。

We can stimulate bone formation with tensile stress on a suture of mouse calvaria. Gene expressions of many factors, especially Wnt/beta-catenin family which are involved in bone-cell activity were examined during the stimulated bone formation. We could show the relative expression ratios of some factors at each time point of the experiment. Those results suggested which factors were more important at each stage of the stimulated bone formation.