Diet, genes, and breast cancer risk in case-control studies in Japanese, Japanese Brazilians, and non-Japanese Brazilians

点击翻译按钮获取中文摘要

We examined the association between green tea, calcium, vitamin D intake and the risk of breast cancer in case-control studies in Nagano and Sao Paulo. We further investigated gene-environment interaction using genetic polymorphisms related to these dietary factors. No significant association was found between green tea consumption and breast cancer risk and no significant interaction was observed by potential genetic effect modifiers. An inverse association was suggested between calcium and vitamin D intake, and breast cancer risk. We have investigated gene-environment interaction using genetic polymorphisms related to vitamin D receptor gene and blood level of vitamin D.