Study on health effect of the highly-concentrated methylmercury exposure derived from a cetacean

鲸类动物接触高浓度甲基汞的健康影响研究

• 批准号: 23390168
• 负责人: NAKAMURA Masaaki
• 金额: $ 8.15万
• 依托单位: National Institute for Minamata Disease
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (B)
• 财政年份: 2011
• 资助国家: 日本
• 起止时间: 2011-04-01 至 2014-03-31
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-23390168/
• 关键词: 環境中毒; クジラ; メチル水銀; 健康影響

We investigated the health effects of MeHg exposure in adults. The subjects were 194 residents who resided in Taiji, the birthplace of traditional whaling in Japan. The geometric mean of the hair mercury levels was 14.9 µg/g and hair mercury levels significantly correlated with daily whale meat intake, suggesting that Taiji residents were highly exposed to MeHg by ingesting whale meat. No significant correlations between hair mercury levels and neurological outcomes were observed. NAA/ Cr ratio of the sensory cortex and cerebellum was normal in the MR spectroscopy, suggesting that there was no apparent neuronal loss in these regions. A significantly positive correlation between whole blood mercury and Se levels was observed and the whole blood mercury/Se molar ratios of all subjects were

我们调查了成年人接触甲基汞对健康的影响。研究对象是194名居住在太地町的居民，太地町是日本传统捕鲸的发源地。头发汞含量的几何平均值为14.9 μ g/g，头发汞含量与每日鲸鱼肉摄入量显著相关，表明太地居民通过摄入鲸鱼肉高度暴露于甲基汞。未观察到头发汞含量与神经预后之间的显著相关性。感觉皮层和小脑的NAA/ Cr比值正常，提示该区域未见明显的神经元丢失。全血汞与硒水平呈显著正相关，所有受试者的全血汞/硒摩尔比为

项目成果

国立水俣病総合研究センター

国立水俣病研究中心

Methylmercury exposure and neurological outcomes in Taiji, the birthplace of traditional whaling in Japan

日本传统捕鲸的发源地太地町的甲基汞暴露和神经系统结果

• 发表时间: 2013
• 作者: Nakamura M;Murata K;Nakanishi I;Yasutake A;Hachiya N;Miyamoto K;Sakamoto M;Usuki F;Kondo T
• 通讯作者: Kondo T

Methylmercury exposure and neurological outcomes in Taiji residents accustomed to consuming whale meat

• DOI: 10.1016/j.envint.2014.03.005
• 发表时间: 2014-07-01
• 期刊: ENVIRONMENT INTERNATIONAL
• 影响因子: 11.8
• 作者: Nakamura, Masaald;Hachiya, Noriyuki;Sakamoto, Mineshi
• 通讯作者: Sakamoto, Mineshi

Methylmercury exposure and neurological outcomes in Taiji, the birthplace of traditional whaling in Japan.

日本传统捕鲸的发源地太地町的甲基汞暴露和神经系统结果。

• 发表时间: 2013
• 作者: Nakamura M;Murata K; Nakanishi I;Yasutake A; Hachiya N;Miyamoto K; Sakamoto M;Usuki F;Kondo T
• 通讯作者: Kondo T