Synthesis of macrocycles using bis(carbonylamino)pyridine unit

使用双(羰基氨基)吡啶单元合成大环化合物

• 批准号: 23550140
• 负责人: YOKOYAMA Akihiro
• 金额: $ 3.41万
• 依托单位: Seikei University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2011
• 资助国家: 日本
• 起止时间: 2011 至 2013
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-23550140/
• 关键词: 大環状化合物; アミド結合

4-Substituted 2,6-diaminopyridine was prepared, and condensation reaction of this compound with terephthaloyl chloride was studied for the synthesis of macrocycles. When the reaction was carried out in 1,4-dioxane at 50 degree with N-ethyldiisopropylamine as a base, the oligomers with moderate molecular weight were obtained. Separation of the crude products afforded the products with desired molecular weight.

4-合成了取代2，6-二氨基吡啶，并研究了其与对苯二甲酰氯的缩合反应，合成了大环化合物。在1，4-二氧六环中，以N-乙基二异丙胺为碱，在50 ℃下进行反应，可得到中等分子量的齐聚物。分离粗产物得到具有所需分子量的产物。

项目成果

Chiral Amplification Based on Sergeants and Soldiers Effect in Helically Folded Poly(naphthalenecarboxamide)

• DOI: 10.1021/ma200055g
• 发表时间: 2011-04
• 期刊: Macromolecules
• 影响因子: 5.5
• 作者: K. Mikami;Hiroaki Daikuhara;Yuko Inagaki;A. Yokoyama;T. Yokozawa

Synthesis of Well-Defined, Water-Soluble Hyperbranched Polyamides by Chain-Growth Condensation Polymerization of AB2 Monomer

• DOI: 10.3390/polym4021170
• 发表时间: 2012-05
• 期刊: Polymers
• 影响因子: 5
• 作者: Y. Ohta;Yusuke Kamijyo;A. Yokoyama;T. Yokozawa

フェニルエステルモノマーを用いた芳香族ラダー型ポリアミドの合成

苯酯单体合成芳香梯形聚酰胺

• 发表时间: 2013
• 作者: T. Sakaguchi;A. Takeda;T. Hashimoto;倉持甚也,岸本一樹,高石和人,横山明弘
• 通讯作者: 倉持甚也,岸本一樹,高石和人,横山明弘

Oxovanadium complexes with quinoline and pyridinone ligands : Syntheses of the complexes and effect of alkyl chains on their apoptosis-inducing activity in leukemia cells

喹啉和吡啶酮配体的氧钒络合物：络合物的合成以及烷基链对其白血病细胞凋亡诱导活性的影响

• DOI: 10.1016/j.bmc.2012.02.063
• 发表时间: 2012
• 期刊: Bioorg. Med. Chem.
• 作者: Tomoko Yamaguchi;Shinya Watanabe;Yuriko Matsumura;Yoshikazu Tokuoka;Akihiro Yokoyama
• 通讯作者: Akihiro Yokoyama

Synthesis of poly(naphthalenecarboxamide)s with low polydispersity by chain-growth condensation polymerization

链增长缩聚法合成低多分散性聚萘甲酰胺

• DOI: 10.1002/pola.24737
• 发表时间: 2011
• 期刊: J. Polym. Sci., Part A : Polym. Chem.
• 作者: Koichiro Mikami;Hiroaki Daikuhara;Jyunya Kasama;Akihiro Yokoyama;Tsutomu Yokozawa
• 通讯作者: Tsutomu Yokozawa