Development of new therapy using novel chimeric oncolytic adenoviruse vector for intractable bladder cancer.
Development of new therapy using novel chimeric oncolytic adenoviruse vector for intractable bladder cancer.
批准号:
23592354
负责人:
GOTOH Akinobu
金额:
$3.24万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2011
资助国家:
日本
项目状态:
已结题
起止时间:
2011 至 2013
中文摘要
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英文摘要
In this study, we examined whether the fiber knob substituted adenovirus vector enhance the therapeutic effect of gene therapy for human bladder cancer which do not have a significant effect on therapeutic outcome of adenovirus gene therapy. Our data showed the novel fiber knob substituted adenovirus vector, Ad5F35/MK, is more useful for the gene therapy of bladder cancer than the non fiber knob substituted Ad5/MK is for human bladder cancer in vitro and in vivo.
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Antitumor Effect of Alpha1-Adrenoceptor Blockers on Human Urological Cancer Cells(泌尿器系癌に対するα1ブロッカーの抗腫瘍効果の検討)
α1-肾上腺素受体阻滞剂对人泌尿系癌细胞的抗肿瘤作用
DOI:
--
发表时间:
2013
期刊:
影响因子:
--
作者:
[Nagaya H, Tagawa M, Hiwasa K, Terao S, Kanno T, Nishizaki T Gotoh A., 長屋寿雄,中川佑介,宮田剛彰,下村欣也,小山倫浩,後藤章暢, 長屋寿雄,中川佑介,宮田剛彰,下村欣也,日和佐一弘,中野孝司,西崎知之,後藤章暢, 中川佑介,長屋寿雄,宮田剛彰,下村欣也,日和佐一弘,西崎知之,後藤章暢]
通讯作者:
中川佑介,長屋寿雄,宮田剛彰,下村欣也,日和佐一弘,西崎知之,後藤章暢
DOI:
10.1159/000350108
发表时间:
2013-01-01
期刊:
CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
影响因子:
--
作者:
[Niba, Emma Tabe Eko, Nagaya, Hisao, Nishizaki, Tomoyuki]
通讯作者:
Nishizaki, Tomoyuki
生薬成分と分子標的薬を用いた併用療法によるがん治療のための基礎研究
使用草药成分和分子靶向药物联合治疗癌症的基础研究
DOI:
--
发表时间:
2014
期刊:
影响因子:
--
作者:
[Nagaya H, Tagawa M, Hiwasa K, Terao S, Kanno T, Nishizaki T Gotoh A., 長屋寿雄,中川佑介,宮田剛彰,下村欣也,小山倫浩,後藤章暢]
通讯作者:
長屋寿雄,中川佑介,宮田剛彰,下村欣也,小山倫浩,後藤章暢
Naftopidil induces apoptosis in malignant mesothelioma cell lines independently ofα1-adrenoceptor blocking
萘哌地尔诱导恶性间皮瘤细胞系凋亡,与α1-肾上腺素受体阻断无关
DOI:
--
发表时间:
2013
期刊:
Anticancer Res
影响因子:
2
作者:
[Masachika E, Kanno T, Nakano T, Gotoh A, Nishizaki T]
通讯作者:
Nishizaki T
Antitumor Effect of Alpha1-Adrenoceptor Blockers on Human Urological Cancer Cells(泌尿器系癌に対するα1ブロッカーの抗腫瘍効果の検討).
α1-肾上腺素受体阻滞剂对人类泌尿癌细胞的抗肿瘤作用。
DOI:
--
发表时间:
2013
期刊:
影响因子:
--
作者:
[中川佑介, 長屋寿雄, 宮田剛彰, 下村欣也, 日和佐一弘, 西崎知之, 後藤章暢]
通讯作者:
後藤章暢
共 13 条
The assessment using Positron Emission Tomography in conditionally replicating adenovirus therapy.
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批准号:19390420
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$11.15万
-
财政年份:2007
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负责人:GOTOH Akinobu
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依托单位:
The Assessment of gene therapy for bone metastatic lesion of prostate cancer, using Positron Emission Tomography.
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批准号:16390464
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$8.77万
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财政年份:2004
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负责人:GOTOH Akinobu
-
依托单位:
Development of testicular tumor gene therapy using human testicular tumor cell-specific promoters
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批准号:12671530
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$1.09万
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财政年份:2000
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负责人:GOTOH Akinobu
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依托单位:
Basic Research into Clinical Application of Gene Therapy for Prostate Cancer
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批准号:09671628
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$1.66万
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财政年份:1997
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负责人:GOTOH Akinobu
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依托单位:
海外基金