Establishment of a new treatment for xerostomia focused on salivary secretion mechanism of chewing

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Saliva have a crucial role to facilitate bolus formation and swallowing during mastication. It is well-known that there is a significant relationship between chewing and saliva, but it remains poorly understood. Therefore, the purpose of this study was to validate the stimulus saliva during mastication and the muscle activity of mastication related muscle, and to elucidate the relationship between jaw movement and salivary secretion mechanism. As a result, P-area of the cerebral cortex mastication area controls salivation and jaw movement simultaneously, and the result indicates that there is the high correlation between the frequency ofjaw movement and the amount of salivary secretion.