Elucidation of behavior and functions of a dendritic cell subset with high crosspresenting activity
Elucidation of behavior and functions of a dendritic cell subset with high crosspresenting activity
批准号:
23659245
负责人:
KAISHO Tsuneyasu
金额:
$2.41万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Challenging Exploratory Research
财政年份:
2011
资助国家:
日本
项目状态:
已结题
起止时间:
2011 至 2012
中文摘要
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英文摘要
CD8α/CD103^<+>CD11b^<- >dendritic cell (DC) is one DC subset, which is characterized by its high ability to ingest dead cells and crosspresent antigens to generate CD8 T cell responses. We have generated knock-in mice in which CD8α/CD103+CD11bDC can be tracked and ablated and clarified in vivo distribution and functions of CD8α/CD103+CD11bDC. The mice can be applied to various experimental models and should be useful to reveal the novel functions of CD8α/CD103+CD11bDC.
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The role of M cells in intestinal immunity
M细胞在肠道免疫中的作用
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[Yoshio S, Kanto T, Matsubara T, Sugiyama M, Murata K,, Fukuhara T, Matsuura Y, Mizokami M, Hayashi N, Takehara T, T. Kanaya]
通讯作者:
T. Kanaya
A chemokine system in CD8 positive dendritic cells
CD8阳性树突状细胞中的趋化因子系统
DOI:
--
发表时间:
2012
期刊:
Cytometry Research
影响因子:
--
作者:
[邊見弘明, 山崎千尋, 星野克明, 改正恒康]
通讯作者:
改正恒康
Analysis of in vivo function of XC chemokine receptor-expressing dendric cells.
表达 XC 趋化因子受体的树突状细胞的体内功能分析。
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[M. Sugiyama, H. Hemmi, C. Yamazaki, T. Ohta, I. Sasaki, K. Hoshino, T. Kaisho]
通讯作者:
T. Kaisho
ABLATION OF A DENDRITIC CELL SUBSET EXPRESSING XC CHEMOKINE RECEPTOR 1 IN VIVO
体内表达 XC 趋化因子受体 1 的树突状细胞亚群的消融
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[Suzuki N, Yamazaki S, Yamaguchi T, Takaki S, Nakauchi H, Keizo Takao, Hiroaki Hemmi]
通讯作者:
Hiroaki Hemmi
The Ets transcription factor Spi-B is essential for M-cell differentiation
Ets 转录因子 Spi-B 对于 M 细胞分化至关重要
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[Obata Y., et al, 瀬戸口 留可, 瀬戸口 留可, Kanaya Takashi 他,]
通讯作者:
Kanaya Takashi 他,
共 60 条
Clarification of molecular mechanisms for regulating dendritic cell subset functions
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批准号:23390124
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$12.73万
-
财政年份:2011
-
负责人:KAISHO Tsuneyasu
-
依托单位:
Molecular mechanisms for type I interferon production by Toll-like receptor-stimulated dendritic cells
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批准号:20390146
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$11.4万
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财政年份:2008
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负责人:KAISHO Tsuneyasu
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依托单位:
Dendritic cell activation mechanisms by nucleic by nucleic acid immune adjuvants.
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批准号:18590483
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.57万
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财政年份:2006
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负责人:KAISHO Tsuneyasu
-
依托单位:
Identification of novel immune adjuvants and their acting mechanism on dendritic cell function
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批准号:16590403
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.3万
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财政年份:2004
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负责人:KAISHO Tsuneyasu
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依托单位:
Dendritic cell activation mechanism by Toll-like receptors
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批准号:14570280
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.24万
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财政年份:2002
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负责人:KAISHO Tsuneyasu
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依托单位:
Mechanism of NK cell dysfunction in C/EBP-γ deficient mice
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批准号:12670304
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.18万
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财政年份:2000
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负责人:KAISHO Tsuneyasu
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依托单位:
Mechanism of B cell proliferation and diffentiation in peripheral lymphoid organs
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批准号:10670313
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.3万
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财政年份:1998
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负责人:KAISHO Tsuneyasu
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依托单位:
海外基金