Study of development of the tumor imaging method using fumarate metabolism
Study of development of the tumor imaging method using fumarate metabolism
批准号:
23659602
负责人:
MATSUMOTO Yuji
金额:
$2.33万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Challenging Exploratory Research
财政年份:
2011
资助国家:
日本
项目状态:
已结题
起止时间:
2011 至 2012
中文摘要
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英文摘要
The tumor imaging is one of the main study domains in nuclear medicine, and FDG PET has been already used in the clinical site. However, these do not specifically accumulate in a malignant tumor, and development of new tumor imaging preparation is hoped for.It is said that the cancer cell perform fumarate metabolism unlike the mammalian normal cell. Thus, tumor imaging based on mechanism unlike a conventional manner will be established if the radionuclide that can image fumarate metabolism is developed. We tried the development of a radionuclide enabling imaging of the fumarate metabolism in this study.
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酸素不足を指標とする PET用診断薬の合成研究(3)
以缺氧为指标的PET诊断试剂的合成研究(3)
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[齋藤 茂芳, 澤田 和彦, 村瀬 研也, 佐賀 恒夫, 青木 伊知男, 小林俊夫,栗山拓也,長野間千瑛,小島良紀,西谷潔]
通讯作者:
小林俊夫,栗山拓也,長野間千瑛,小島良紀,西谷潔
高いクリアランス能を有する新規低酸素PETプローブの開発
新型高清除能力缺氧PET探针的研制
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[木村禎亮, 栗山拓也, 小島良紀, 梅田泉, 藤井博史]
通讯作者:
藤井博史
A novel PET probe for tumor hypoxia imaging with excellent renal clearance.
一种用于肿瘤缺氧成像的新型 PET 探针,具有出色的肾清除率。
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[Kimura S, Kuriyama T, Kojima YK, Umeda IO, Moriyama N, Fujii H]
通讯作者:
Fujii H
投与後早期のイメージングが可能な新規低酸素PET プローブの開発
开发新型低氧 PET 探针,可在给药后进行早期成像
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[木村禎亮, 栗山拓也, 小島良紀, 梅田泉, 藤井博史]
通讯作者:
藤井博史
新規腫瘍選択性の向上を目指した新規低酸素PETプローブの合成と評価
旨在提高肿瘤选择性的新型低氧 PET 探针的合成和评估
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[栗山拓也, 小島良紀, 木村禎亮, 梅田泉, 西谷潔, 小島周二, 藤井博史]
通讯作者:
藤井博史
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Joint Natural Language Processing with Global Information
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Metallic glass flux-vapor growth of SiC single crystal films
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Analysis of chemical nature and interaction of cell wall components by the use of wood cell wall solvent system
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Role of muscarinic acetylcholine receptor in the development of transplant arteriosclerosis
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Photoelectrochemistry of hetero-structured epitaxial TiO_2 electrodes
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Blackboard and Table in Paperless Age: Development of CAD Oriented Roomware for Architectural Design Esquisse
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Role of ADP receptor (P2Y12) in the development of transplant arteriosclerosis
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How does the structure of lignin correspond to mechanical circumstances
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Exploration of new spintronics materials by vapor phase epitaxy approach
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