Spatio-temporal control of artificial cell system based on microfluidic technology

近年来，人工细胞系统得到了积极的研究。生物分子反应系统如基因表达系统被封闭在由细胞大小的小泡构成的人工细胞中。然而，迄今为止，在基于这些人工系统的人工细胞中还没有实现动力学现象。在本研究中，我们成功地开发了基本技术，以实现动态现象，如自主反应和运动的人工细胞使用微流体技术，它可以精确地控制一个微小的体积的流体。

In recent years, artificial cell systems have been actively studies. Biomolecular reaction systems such as gene expression systems are enclosed In the artificial cells constructed with cell-sized small vesicles. However, up to date,dynamic phenomena have not been realized in artificial cells based on those artificial systems yet. In this study, we succeeded in the development of basic technologies to realize dynamic phenomena such as autonomous reactions and motions of artificial cells using microfluidic technology, which can precisely control a tiny volume of fluids.