Study on a microglial phenotypic switch with a focus on proteolytic response
Study on a microglial phenotypic switch with a focus on proteolytic response
批准号:
15H05015
负责人:
Nakanishi Hiroshi
金额:
$10.98万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B)
财政年份:
2015
资助国家:
日本
项目状态:
已结题
起止时间:
2015-04-01 至 2018-03-31
中文摘要
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英文摘要
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Cathepsin H deficiency in mice induces excess Th1 cell activation and early-onset of EAE through impairment toll-like receptor 3 cascade.
小鼠组织蛋白酶 H 缺乏会通过损害 Toll 样受体 3 级联来诱导 Th1 细胞过度激活和 EAE 早发。
DOI:
--
发表时间:
2018
期刊:
Inflamm Res
影响因子:
6.7
作者:
[Okada R, Zhang Z, Harada Y, Wu Z, Nakanishi H]
通讯作者:
Nakanishi H
DOI:
10.1523/jneurosci.1599-15.2015
发表时间:
2015-09-09
期刊:
JOURNAL OF NEUROSCIENCE
影响因子:
5.3
作者:
[Ni, Junjun, Wu, Zhou, Nakanishi, Hiroshi]
通讯作者:
Nakanishi, Hiroshi
L-10 plays a pivotal role in anti-inflammatory effects of Pheum tanguticum in activated microglia
L-10 在活化小胶质细胞中唐古特苯的抗炎作用中发挥关键作用
DOI:
--
发表时间:
2017
期刊:
影响因子:
--
作者:
[Jie Meng, Junjun Ni, Zhou Wu, Aiquin Zhu, Hiroshi Nakanishi]
通讯作者:
Hiroshi Nakanishi
Porphyromonas gingivalis promotes cell migration and an inflammatory response of microglia through the gingipain-mediated activation of protease-activated receptor-2.
牙龈卟啉单胞菌通过牙龈蛋白酶介导的蛋白酶激活受体 2 的激活促进细胞迁移和小胶质细胞的炎症反应。
DOI:
--
发表时间:
2017
期刊:
影响因子:
--
作者:
[Liu Y, Wu Z, Nakanishi H]
通讯作者:
Nakanishi H
IL-10 plays a pivotal role in anti-inflammatory effects of Rheum tanguticum in activated microglia.
IL-10 在唐古特大黄对活化小胶质细胞的抗炎作用中发挥着关键作用。
DOI:
--
发表时间:
2017
期刊:
影响因子:
--
作者:
[Meng J, Ni J, Wu Z, Zhu A, Nakanishi H]
通讯作者:
Nakanishi H
共 29 条
The Effect of Prosody Shadowing on Automatization of Syntactic Processing
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批准号:19K00855
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.33万
-
财政年份:2019
-
负责人:Nakanishi Hiroshi
-
依托单位:
Possible involvement of impaired intrinsic microglial clock in Periodontotis-associated exacerbation of Alzheimer's disease
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批准号:18K19650
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项目类别:Grant-in-Aid for Challenging Research (Exploratory)
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资助金额:$4.08万
-
财政年份:2018
-
负责人:Nakanishi Hiroshi
-
依托单位:
Analysis for the mechanism of sensorineural hearing loss caused by cochlear autoinflammation
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批准号:17K11324
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.75万
-
财政年份:2017
-
负责人:Nakanishi Hiroshi
-
依托单位:
Theoretical design study on molecular bridge devices
-
批准号:16K04876
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$3.16万
-
财政年份:2016
-
负责人:Nakanishi Hiroshi
-
依托单位:
Analysis of Porphyromonas gingivalis-induced neuroinflammation by multi-photon imaging of microglia dynamics
-
批准号:15K15684
-
项目类别:Grant-in-Aid for Challenging Exploratory Research
-
资助金额:$2.33万
-
财政年份:2015
-
负责人:Nakanishi Hiroshi
-
依托单位:
Evaluation of autoinflammatory responses in mouse cochlea
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批准号:15H06255
-
项目类别:Grant-in-Aid for Research Activity Start-up
-
资助金额:$1.58万
-
财政年份:2015
-
负责人:Nakanishi Hiroshi
-
依托单位:
The Relation of Working Memory Capacity with Processing of Filler-Gap Sentences
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批准号:26770197
-
项目类别:Grant-in-Aid for Young Scientists (B)
-
资助金额:$0.92万
-
财政年份:2014
-
负责人:Nakanishi Hiroshi
-
依托单位:
海外基金