Development of inhibitors based on the molecular structure and mechanism of substrate hydrolysis by metallo-beta-lactamases
Development of inhibitors based on the molecular structure and mechanism of substrate hydrolysis by metallo-beta-lactamases
批准号:
26460147
负责人:
KUROSAKI Hiromasa
金额:
$3.16万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2014
资助国家:
日本
项目状态:
已结题
起止时间:
2014-04-01 至 2017-03-31
中文摘要
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英文摘要
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Acinetobacter spp.由来のメタロ-β-ラクタマーゼ(IMP-2)の結晶構造
不动杆菌属金属-β-内酰胺酶 (IMP-2) 的晶体结构。
DOI:
--
发表时间:
2014
期刊:
影响因子:
--
作者:
[山口佳宏, 松枝 聖, 松永和代, 髙潮信寿, 藤間-深井祥子, 山縣ゆり子, 柴田尚宏, 和知野純一, 柴山恵吾, 荒川宜親, 黒 博雅]
通讯作者:
黒 博雅
Development of fluorescent probes for metallo-beta-lactamase-producing Gram-negative bacteria
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批准号:24659054
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项目类别:Grant-in-Aid for Challenging Exploratory Research
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资助金额:$2.41万
-
财政年份:2012
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负责人:KUROSAKI Hiromasa
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依托单位:
Development of irreversible inhibitors forβ-lactam inactived enzyme, metallo-β-lactamase
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批准号:21590116
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$3.0万
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财政年份:2009
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负责人:KUROSAKI Hiromasa
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依托单位:
Structure-based Design of Selective metallo-β-lactamase
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批准号:18390038
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$10.63万
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财政年份:2006
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负责人:KUROSAKI Hiromasa
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依托单位:
Development of functional molecules capable of recognizing and cleaving the bulge structure in DNA by using an optical active dinuclear iron complex
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批准号:16590031
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.37万
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财政年份:2004
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负责人:KUROSAKI Hiromasa
-
依托单位:
Sequence specific double-strand DNA cleavage by an optical active dinuclear iron complex and application for artificial restriction enzyme
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批准号:14572034
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.18万
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财政年份:2002
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负责人:KUROSAKI Hiromasa
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依托单位:
海外基金