Endocrinology and Reproductive Physiology Training Grant

抽象的。内分泌学和生殖生理学(ERP)研究生培训计划是 长期专注于生殖的跨学科内分泌计划。因此，ITS的一个主要焦点是 研究人员涉及NICHD的许多重点领域，即生殖生物学和生理学、孕产妇健康、 和胎儿健康水平的宫内计划和成人发病的起源。这是实现的 使用干细胞和细胞/分子生物学的多学科方法来比较生理学 动物模型在非人类灵长类动物和人类身上进行翻译工作。自2014年以来，我们继续展示 在少数族裔招募和培训方面的卓越表现，以及我们培训计划的进一步演变 增加了一门先进的负责任的研究和专业发展课程。这个 我们受训人员的成果在出版物和就业方面都很出色，并充分 详情如下。在过去的三年里，我们看到人类翻译研究的增加 多学科和跨学科团队，成员既有医学博士又有博士学位。我们已经看到了一个 对生殖以及成人结局研究感兴趣的MD和MD/PhD培训人员的数量急剧增加 由早产/低出生体重引起的疾病(肥胖、糖尿病、高血压)本身可能 会导致复杂的妊娠。我们继续在ERP的学位奖学金轨道上培训MD研究员。 虽然医学博士候选人通常不是T32博士前申请支持的候选人，但我们希望 审查员要意识到在企业资源规划中存在这一轨道，因为这对 医学博士后和博士后实习生。最终的结果是一次更强大、更有活力的训练 招聘更多的医学博士和博士教师，更有利于/支持的环境 翻译研究。如果我们想要保持未来，这种混合的训练环境是非常必要的 跨学科翻译研究团队成员，以追求以下研究和翻译目标 NICHD改善公共健康，因为它与怀孕和生殖有关。

Abstract. The Endocrinology and Reproductive Physiology (ERP) Graduate Training Program is an interdisciplinary endocrine program with a longstanding focus on reproduction. As such, a major focus of its researchers relates to many focus areas of NICHD, ie reproductive biology and physiology, maternal health, and fetal health at the level of intrauterine programming and the origins of adult onset disease. This is achieved using multidisciplinary approaches from stem cells and cellular/molecular biology to comparative physiology of animals models to translational work in nonhuman primates and humans. Since 2014 we continue to show excellence in minority recruitment and training, and the further evolution of our training program continues with the addition of an advanced responsible conduct of research and professional development course. The outcomes for our trainees have been outstanding both in terms of publications and placement, and are fully detailed below. In the past three years we have seen an increase in human translational studies by multidisciplinary and interdisciplinary teams, the members of which are both MD and PhD. We have seen a dramatic increase in MD and MD/PhD trainers interested in reproduction as well of the study of adult outcome diseases (obesity, diabetes, hypertension) caused by prematurity/low birthweight and which themselves may lead to complicated pregnancy. We continue to train MD fellows in our Degree Fellowship Track within ERP. While MD candidates are not typically candidates for support under this T32 Predoctoral application, we wish the reviewers to be aware of the existence of this track within ERP as this impacts greatly on the experience of both MD postdoctoral and PhD Predoctoral trainees. The end result is a stronger, more vibrant training environment which, with the recruitment of additional MD and PhD faculty, is more conducive/supportive of translational research. This blended training environment is very much needed if we are to maintain a future pool of interdisciplinary translational research team members to pursue the research and translational goals of NICHD to improve public health as it relates to pregnancy and reproduction.