权益分类	功能权益	普通用户	{{item.name}}会员
{{category.name}}	{{benefitItem.name}}

Collaborating Consortium of Cohorts Producing NIDA Opportunities (C3PNO)

产生 NIDA 机会的群体合作联盟 (C3PNO)

基本信息

批准号：
10165380
负责人：
Pamina Mae Gorbach
金额：
$ 32.61万
依托单位：
UNIVERSITY OF CALIFORNIA LOS ANGELES
依托单位国家：
美国
项目类别：
财政年份：
2017
资助国家：
美国
起止时间：
2017-05-01 至 2022-03-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10165380
关键词：
2019-nCoV AIDS prevention Address Adherence Administrative Supplement Adolescent Medicine Trials Network Affect Alcohol or Other Drugs use Anxiety Appointment Area Baltimore Behavior COVID-19 COVID-19 pandemic Cannabis Caring Chicago Cities Cohort Studies Collection Communities Continuity of Patient Care Counseling Data Drug usage Family Food Frequencies Funding Funding Opportunities HIV HIV Infections HIV Seronegativity HIV Seropositivity HIV prevention trials network Health Height Home environment Housing Individual Infrastructure Injections Interruption Link Los Angeles Measures Medical Records Mental Health Methamphetamine NIH Program Announcements National Institute of Drug Abuse North America Opioid Participant Patient Self-Report Pharmaceutical Preparations Population Population Group Prevalence Prevention Research Risk Factors Science Smoking Social isolation Specific qualifier value Substance Use Disorder Surveys Time Tobacco Vulnerable Populations addiction antiretroviral therapy base cohort data harmonization design experience food insecurity frontier high risk innovation interest intimate partner violence marijuana vaping neurodevelopment novel opioid use disorder pre-exposure prophylaxis prescription opioid public health emergency response social stimulant use vaping young men who have sex with men

项目摘要

ABSTRACT In response to the Notice of Special Interest (NOSI) regarding the Availability of Administrative Supplements and Urgent Competitive Revisions for Research on the 2019 Novel Coronavirus (Notice Number NOT-DA-20-047 and linked Program Announcement PA-18-591) funding opportunity, the Collaborating Consortium of Cohorts Producing NIDA Opportunities (C3PNO; U24DA044554) proposes a project to assess the impact of COVID-19 on the participating cohorts' population of substance-using people living with HIV (PLWH) and those at high-risk for HIV infection. Our innovative study proposes to collect data from a subset of participants from each of seven participating C3PNO cohorts at two time points – in the height of the COVID-19 pandemic and during its mitigation and control – in order to assess the impact of the COVID-19 epidemic on substance use for PLWH and those at high risk for HIV. We will use our current infrastructure and C3PNO validated harmonization strategies to compile new and existing data across the cohorts in order to: assess changes in social and individual determinants of health during the course of the COVID-19 pandemic, to estimate differences in substance-using behaviors of those who were confirmed/probable cases of COVID-19 (based on self-report or medical record) and those who were not a confirmed/probable case, and to assess how PLWH and people who are at high risk for HIV in C3PNO have different experiences in and responses to the COVID-19 epidemic as compared to other HIV studies and cohorts that have less substance use. The C3PNO Coordinating Center at UCLA and Frontier Science will facilitate the design and implementation of a survey to collect data from a subset of participants from each of seven participating C3PNO cohorts (ALIVE, HYM, JHHCC, MASH, mSTUDY, RADAR, and V-DUS). Participating cohorts will issue the survey to participants and transfer the resulting data to the coordinating center. If funded, this administrative supplement would allow a rapid and coordinated collection of linked COVID-19, HIV, and substance use data related to an ongoing public health emergency affecting the highly vulnerable substance-using populations followed by the cohorts. COVID-19 data harmonization with other HIV cohorts will further aide our collective effort to understand the impact of COVID-19 on HIV impacted communities. Finally, C3PNO's effort to assess changes in social and individual determinants of health during the course of the COVID-19 pandemic as well as estimate differences in substance-using behaviors and the impact on PLWH or at high risk for HIV is both novel and critical in this time of unprecedented social upheaval and instability.

摘要