Administrative Core
行政核心
基本信息
- 批准号:10224302
- 负责人:
- 金额:$ 14.72万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2020
- 资助国家:美国
- 起止时间:2020-07-28 至 2025-05-31
- 项目状态:未结题
- 来源:
- 关键词:AdultAreaAttentionBehavioralBiological ModelsBrainChild CareClinicalCollaborationsCore FacilityDevelopmentDevelopmental DisabilitiesDown SyndromeEducationEnsureEnvironmentEtiologyEvolutionExtramural ActivitiesFacultyFundingFutureGeneticGenomeHeadHumanIndividualInfrastructureInstitutesIntellectual and Developmental Disabilities Research CentersIntellectual functioning disabilityInterruptionInvestmentsKnowledgeLaboratoriesLeadershipMental HealthMicrocephalyMissionMissouriModelingNational Institute of Child Health and Human DevelopmentNeurodevelopmental DisabilityPathogenicityPediatric NeurologyPhasePhenotypePreventionProviderPsychiatryResearchResearch PersonnelResearch TrainingResourcesRoleScienceSeriesStructureSystemTimeTraining ProgramsTranslationsUnited States National Institutes of HealthUniversitiesWashingtonZika Virusbasebrain abnormalitiescohesioncost effectivedesigndisabilitydual diagnosisfrontierfunctional genomicsimprovedmemberneuroimagingoperationpersonalized medicinepost-doctoral trainingprematurepreventprogramsresearch facilitystandard of caretranslational pipeline
项目摘要
Administrative Core Project Abstract
In this application we present a core scientific structure that is specifically designed to support scientific effort
along the overarching themes of prematurity prevention and advancing personalized medicine approaches to
IDD; for the latter, utilizing expertise in the elucidation of intermediate phenotypes, advancing characterization
of the developing human brain, and infrastructures for functional genomic studies. The Administrative Core
assumes responsibility for scientific oversight as an integrated Center that is a discovery pipeline for translational
advances in IDD research. The Specific Aims are: 1) To sustain an effective system of management of the day-
to-day operation of the Center’s funds and resources, which includes the efficient flow of necessary resources
to maintain three efficient, cost-effective, state-of-the-art core scientific facilities that constitute a critical
infrastructure for IDD research in the WUSTL environment: the Model Systems Core (MSC), the Developmental
Neuroimaging Core (DNC), and the Clinical-Translational Core (CTC); 2) To stimulate intramural and extramural
scientific collaboration and discovery along key frontiers of IDD research and 3) To disseminate new knowledge
and implement practice improvements that are based upon new discovery, through partnerships with the
University Centers of Excellence in Developmental Disabilities (UCEDDs), Leadership Education in
Neurodevelopmental Disabilities (LENDs), the Missouri Dept. of Mental Health, regional clinical providers, and
other external entities involved in the care of children and adults with developmental disabilities.
行政核心项目摘要
在这个应用程序中,我们提出了一个核心的科学结构,是专门设计来支持科学工作
沿着早产预防和推进个性化医疗方法的总体主题,
IDD;对于后者,利用中间表型阐明方面的专业知识,推进表征
以及功能基因组研究的基础设施。行政核心
承担科学监督的责任,作为一个综合中心,这是一个发现的转化管道
缺碘症研究的进展。具体目标是:1)维持一个有效的日常管理系统-
中心资金和资源的日常运作,包括必要资源的有效流动
维持三个高效,具有成本效益,最先进的核心科学设施,构成一个关键的
在WUSTL环境中IDD研究的基础设施:模型系统核心(MSC),开发
神经影像学核心(DNC)和临床转化核心(CTC); 2)刺激壁内和壁外
沿着缺碘症研究的关键前沿开展科学合作和发现; 3)传播新知识
并通过与
发展障碍卓越大学中心(UCEDDs),领导力教育,
神经发育障碍(LEND),密苏里州部门。心理健康,区域临床提供者,以及
参与照料发育残疾儿童和成人的其他外部实体。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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JOHN N. CONSTANTINO其他文献
JOHN N. CONSTANTINO的其他文献
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{{ truncateString('JOHN N. CONSTANTINO', 18)}}的其他基金
Missouri Study to Explore Early Development (SEED) Follow-Up
密苏里州研究探索早期发育 (SEED) 后续行动
- 批准号:
10408656 - 财政年份:2021
- 资助金额:
$ 14.72万 - 项目类别:
Missouri Study to Explore Early Development (SEED) Follow-Up
密苏里州研究探索早期发育 (SEED) 后续行动
- 批准号:
10300870 - 财政年份:2021
- 资助金额:
$ 14.72万 - 项目类别:
Missouri Study to Explore Early Development (SEED) Follow-Up
密苏里州研究探索早期发育 (SEED) 后续行动
- 批准号:
10631976 - 财政年份:2021
- 资助金额:
$ 14.72万 - 项目类别:
Harnessing Clinical Genomic Characterization to Accelerate Translational Advances for Patients with IDD
利用临床基因组特征加速 IDD 患者的转化进展
- 批准号:
9976668 - 财政年份:2020
- 资助金额:
$ 14.72万 - 项目类别:
Harnessing Clinical Genomic Characterization to Accelerate Translational Advances for Patients with IDD
利用临床基因组特征加速 IDD 患者的转化进展
- 批准号:
10159337 - 财政年份:2020
- 资助金额:
$ 14.72万 - 项目类别:
Washington University Intellectual and Developmental Disabilities Research Center
华盛顿大学智力与发育障碍研究中心
- 批准号:
10224301 - 财政年份:2020
- 资助金额:
$ 14.72万 - 项目类别:
Washington University Intellectual and Developmental Disabilities Research Center
华盛顿大学智力与发育障碍研究中心
- 批准号:
10085124 - 财政年份:2020
- 资助金额:
$ 14.72万 - 项目类别:
Identification of Newborns at High Risk for the Occurrence of Preventable Child Maltreatment
识别发生可预防的儿童虐待的高风险新生儿
- 批准号:
10475106 - 财政年份:2018
- 资助金额:
$ 14.72万 - 项目类别:
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