Admin-Core-001

标题：与服务不足/弱势群体合作消除亚利桑那州的COVID-19差距 社区 摘要 亚利桑那州是美国COVID-19阳性检测率最高的州之一（约19%）。 在亚利桑那州的拉丁裔、美洲印第安人和非洲裔美国人社区中，这一比例要高得多。 拟议的社区驱动和文化一致的干预措施旨在增加获得检测的机会， 确定并减少亚利桑那州脆弱和服务不足社区的测试障碍。的 干预旨在减少COVID-19诊断、教育、概括性服务和 转诊到初级保健提供者，最终目标是改善服务不足社区的健康状况。 所提出的方法赋予当地社区权力，满足社区成员的需要， 并为持续的社区驱动的护理提供创造基础设施。 根据以社区为基础的前瞻性研究（CBPR）的方向，该项目将：（a）确定 并优先考虑测试沙漠，（B）协调社会生态系统不同层面的测试，（c）参与并 培训当地社区卫生工作者（CHW），为弱势群体提供唾液COVID-19检测， （d）在72小时内提供检测结果，（e）提供综合服务 和提供者转介那些检测呈阳性的人，以及（f）在后续期间维持干预措施。 平等健康基金会是一个不断增长的COVID-19的主要社区合作伙伴和召集人， 19来自亚利桑那州各地的颜色合作伙伴社区联盟（CCCCP）。ASU Biodesign临床 检测实验室（ABCTL）将提供基于唾液的SARS-CoV-2分子诊断。唾液测试 主要优点是：a）与鼻咽拭子（NP）相比，PPE要求最低或无PPE要求; B） 标本采集的便利性和经济性; c）易于重复采样; d）最低限度地 受过训练的CHW和e）唾液测试比NP拭子更高的灵敏度和一致性。该项目旨在 管理29，000次唾液测试，在启动期间在确定的测试沙漠进行10，000 - 12，000次测试， 第一年随访期间的数量，第二年增加5,000次测试。纵向评价 将通过比较R.A.P.I.D.中随机选择的参与者来评估干预的影响。干预 在上市期间（N=500），随机选择匹配的对照组（N=500）， 标准测试场地。 亚利桑那州立大学现有的NIMHD资助的U 54专业卓越中心（RFA-MD-17-005; 5 U 54 MD 002316 -14）及其社区咨询委员会，并与主要政府、社区 组织，部落政府和学术合作伙伴装备精良，有资格承担 拟议修订。本次紧急竞争性修订的目的与当前竞争性修订的目的相匹配并增强了竞争性修订的目的。 U 54奖和组装的跨学科团队具有基础设施，能力和社区 为实施该项目建立了伙伴关系。

Title: Eliminating COVID-19 disparities in Arizona in partnership with underserved/vulnerable communities Abstract Arizona has one of the highest COVID-19 positivity test rates (approximately 19%) in the U.S. Positivity rates are disproportionally higher among Arizona's Latinx, American Indian and African American communities. The proposed community driven and culturally congruent intervention aims to increase access to testing by identifying and decreasing barriers to testing in vulnerable and underserved communities across Arizona. The intervention aims at reducing disparities in COVID-19 diagnostics, education, wraparound services and referrals to a primary care provider, with the ultimate goal of improving the health of underserved communities. The proposed approach empowers local communities, meets community members where they are, is data driven, and creates the infrastructure for continued community-driven delivery of care. Following a Community Based Participatory Research (CBPR) orientation, the project will: (a) identify and prioritize testing deserts, (b) coordinate testing at different levels of the social ecosystem, (c) engage and train local Community Health Workers (CHWs) deliver saliva-based COVID-19 testing to vulnerable and underserved community members, (d) deliver test results within 72 hours, (e) provide wrap-around services and provider referrals for those testing positive, and (f) sustain the intervention during a follow-up period. Equality Health Foundation serves as the lead community partner and convener of a growing COVID- 19 Coalition of Communities of Color Partners (CCCCP) from across Arizona. The ASU Biodesign Clinical Testing Laboratory (ABCTL) will provide the saliva-based SARS-CoV-2 molecular diagnostic. The saliva test's main benefits are: a) minimal to no PPE requirements compared to nasopharyngeal (NP) swabs; b) convenience and economy of specimen collection; c) ease of repeat sampling; d) administration by minimally trained CHWs and e) greater sensitivity and consistency of saliva tests than NP swabs. The project aims to administer 29,000 saliva tests, 10,000-12,000 at identified testing deserts during the launching period, doubling the numbers during the follow-up period in Year 1, and adding 5,000 tests in Year 2. A longitudinal evaluation will assess the intervention's impact by comparing randomly selected participants in the R.A.P.I.D. intervention during the launching period (N=500) with a matched comparison group (N=500) randomly selected from standard testing sites. ASU's existing NIMHD-funded U54 Specialized Center of Excellence (RFA-MD-17-005; 5U54MD002316-14) with its Community Advisory Board and in collaboration with key government, community organizations, tribal governments and academic partners is well equipped and eligible to undertake the proposed revision. The aims of this emergency competitive revision match and enhance the aims of the current U54 award and the assembled transdisciplinary team has the infrastructure, capacity, and community partnerships in place to implement the project.