'keepin' It REAL in Mexico: An Adaptation and Multisite RCT

在墨西哥“保持”真实：适应和多站点随机对照试验

• 批准号: 9926386
• 负责人: Flavio Francisco Marsiglia
• 金额: $ 0.54万
• 依托单位: ARIZONA STATE UNIVERSITY-TEMPE CAMPUS
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-09-15 至 2020-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9926386
• 关键词: Address; Adherence; Adolescent; Affect; Alcohol consumption; Alcohol or Other Drugs use; Area; Attitude; Behavior; Characteristics; Cities; Communication; Competence; Country; Drug resistance; Drug usage; Educational Curriculum; Elements; Ensure; Feasibility Studies; Feedback; Female; Future Teacher; Gender; Gender Role; Goals; Government; Health; Healthy People 2020; Intervention; Intervention Studies; Knowledge; Latino; Life; Life Experience; Light; Mexican; Mexican Americans; Mexico; Middle School Student; Minority Groups; Modeling; Morbidity - disease rate; Outcome; Participant; Pharmaceutical Preparations; Phase; Pilot Projects; Play; Prevention; Prevention approach; Prevention program; Preventive Intervention; Process; Prodrugs; Public Health; Randomized; Randomized Controlled Trials; Registries; Reporting; Research; Research Personnel; Risk; Risk Behaviors; Role; Sampling; Schools; Science; Self Administration; Series; Side; Site; Students; Subgroup; Surface; Surveys; Testing; Time; Tobacco use; Translational Research; Translations; Victimization; Violence; Work; Youth; adolescent alcohol and drug use; adolescent substance use; base; cost effective; design; efficacy testing; ethnic minority population; evidence base; experience; gender difference; improved; junior high school; male; marijuana use; metropolitan; mortality; perpetrators; phase 1 study; prevent; programs; public health relevance; racial minority; reduced substance use; seventh grade; skills; substance abuse prevention; substance use prevention; success; successful intervention; teacher; universal prevention; vulnerable adolescent

 DESCRIPTION (provided by applicant): Sharp increases in substance use rates among youth in Mexico are a major concern, both in Mexico and the US. Although the Mexican government has elevated substance abuse prevention as a national priority, there are few school-based universal prevention programs to choose from that are culturally grounded, empirically tested, and shown to be efficacious. This study aims to address this gap by adapting, implementing, and testing the keepin' it REAL (kiR) prevention intervention in Mexico's three largest cities: Mexico City, Guadalajara, and Monterrey. kiR is a model program for middle school students on the US National Registry of Effective Programs and Practices, shown to be efficacious and cost-effective in reducing substance use among large multi-ethnic and Mexican American samples in the US. The proposed study will leverage the bi-national research team's expertise in developing and adapting kiR and build upon a series of feasibility studies across Mexico which showed that kiR's core elements are applicable there. However, evidence also suggested that further adaptation is needed to enhance the intervention's cultural fit. During the proposed study's Phase 1, students and teacher-implementers in three schools-one from each of the cities-will provide feedback about the original curriculum and identify culturally and contextually relevant scenarios and examples. The bi-national research team-including original kiR curriculum designers-will collaborate to ensure cultural applicability in Mexico and fidelity to core elements of kiR. In Phase 2, the efficacy of the culturally adapted Mexican version of kiR, relative to the original version of kiR and to a control condition, will be tested through an inten-to-treat analysis in a randomized controlled trial with 4,050 7th grade students in 27 middle schools, 9 from each city. The study will investigate and incorporate into the curriculum gender specific experiences with drug offers and appropriate drug resistance strategies in the Mexican context that may impact the youths' risk of substance use and their responsiveness to prevention programs. In light of rising violence in Mexico, a secondary aim of the study is to investigate how youths' perpetration, victimization, and witnessing of violence may moderate the efficacy of kiR in Mexico. The study will create knowledge relevant to efficacious prevention approaches for Mexican-heritage youth on both sides of the US-Mexico border. Prevention science will be advanced by understanding how culturally influenced gender role norms affect substance use offers, attitudes, and behaviors, as well as the success of universal prevention programs. In addition, the study will add to knowledge on how to execute collaborative, cross-national, translational prevention intervention research.

 描述（由申请人提供）：墨西哥青少年物质使用率急剧上升是墨西哥和美国的一个主要问题。尽管墨西哥政府已将预防药物滥用列为国家优先事项，但很少有基于学校的普遍预防计划可供选择，这些计划具有文化基础、经过实证检验并被证明是有效的。本研究旨在通过在墨西哥城、瓜达拉哈拉和蒙特雷这三个墨西哥最大城市调整、实施和测试 keepin' it REAL (kiR) 预防干预措施来弥补这一差距。 kiR 是美国国家有效计划和实践登记处针对中学生的一个示范计划，在美国的大量多种族和墨西哥裔美国人样本中，该计划在减少药物使用方面被证明是有效且具有成本效益的。拟议的研究将利用两国研究团队在开发和调整 kiR 方面的专业知识，并以墨西哥各地的一系列可行性研究为基础，这些研究表明 kiR 的核心要素适用于墨西哥。然而，证据还表明，需要进一步调整以增强干预措施的文化契合度。在拟议研究的第一阶段，三所学校（每个城市各一所）的学生和教师实施者将提供有关原始课程的反馈，并从文化和背景上进行识别 相关场景和示例。两国研究团队（包括最初的 kiR 课程设计者）将合作确保墨西哥的文化适用性以及对 kiR 核心要素的忠实。在第二阶段，墨西哥文化适应版 kiR 相对于原始版本 kiR 和对照条件的功效，将通过一项随机对照试验的意向治疗分析进行测试，该试验涉及 27 所中学（每个城市 9 所）的 4,050 名七年级学生。该研究将调查墨西哥背景下不同性别的毒品体验和适当的耐药策略，并将其纳入课程，这些经验可能会影响青少年的药物使用风险及其对预防计划的反应。鉴于墨西哥暴力事件不断增加，该研究的第二个目的是调查青少年的暴力行为、受害和目睹暴力行为如何影响墨西哥 kiR 的效果。该研究将为美墨边境两侧的墨西哥裔青年提供与有效预防方法相关的知识。通过了解受文化影响的性别角色规范如何影响物质使用提议、态度和行为以及普遍预防计划的成功，预防科学将得到推进。此外，该研究还将增加有关如何执行协作、跨国、转化性预防干预研究的知识。

项目成果

Using zero-inflated models to explain chronic illness, pain, and complementary and alternative medicine use.

使用零膨胀模型来解释慢性疾病、疼痛以及补充和替代药物的使用。

• DOI: 10.5993/ajhb.35.4.7
• 发表时间: 2011
• 期刊: American journal of health behavior
• 影响因子: 2.3
• 作者: Ayers,StephanieL;Kronenfeld,JennieJ
• 通讯作者: Kronenfeld,JennieJ

The Impact of Major Earthquakes on Students' Emotional Distress and Internalizing Symptoms, Externalizing Behaviors, and Coping During the Implementation of keepin' it REAL-Mexico.

“keepin it REAL-Mexico”实施过程中，重大地震对学生情绪困扰及内化症状、外化行为和应对的影响。

• DOI: 10.1007/s11121-023-01542-0
• 发表时间: 2024
• 期刊: Prevention science : the official journal of the Society for Prevention Research
• 作者: Medina-Mora,MariaElena;Kulis,StephenS;Real,Tania;Nuño-Gutiérrez,BerthaL;Corona,MariaDolores;Cutrín,Olalla;Marsiglia,FlavioF
• 通讯作者: Marsiglia,FlavioF

Use of Violence as a Strategy of Early Adolescents for Rejecting Drug Offers in Mexican Cities.

墨西哥城市早期青少年使用暴力作为拒绝毒品的策略。

• 发表时间: 2022
• 期刊: Revista mexicana de psicologia
• 影响因子: 0.2
• 作者: Cutrín,Olalla;Avalos,MarvynRArévalo;Corona,MDolores;Nuño-Gutiérrez,BerthaL;Medina-Mora,MElena;Real,Tania;Mendoza-Meléndez,MiguelÁngel;Lara-Valencia,Francisco;Ayers,StephanieL;Kulis,StephenS;Marsiglia,FlavioF
• 通讯作者: Marsiglia,FlavioF

The importance of examining movements within the US health care system: sequential logit modeling.

• DOI: 10.1186/1472-6963-10-269
• 发表时间: 2010-09-10
• 期刊: BMC health services research
• 影响因子: 2.8
• 作者: Lee C;Ayers SL;Kronenfeld JJ;Frimpong JA;Rivers PA;Kim SS
• 通讯作者: Kim SS

Testing a Culturally Adapted Youth Substance Use Prevention Program in a Mexican Border City: Mantente REAL.

• DOI: 10.1080/10826084.2020.1858103
• 发表时间: 2021
• 期刊: SUBSTANCE USE & MISUSE
• 影响因子: 2
• 作者: Kulis, Stephen S.;Garcia-Perez, Hilda;Marsiglia, Flavio F.;Ayers, Stephanie L.
• 通讯作者: Ayers, Stephanie L.