Every Little Step Counts

每一步都很重要

• 批准号: 8471192
• 负责人: Flavio Francisco Marsiglia
• 金额: $ 11.72万
• 依托单位: ARIZONA STATE UNIVERSITY-TEMPE CAMPUS
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-02-01 至 2017-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8471192
• 关键词: Address; Adolescent; Affect; Collaborations; Communities; Development; Effectiveness of Interventions; Exhibits; Glucose; Health; Health behavior; Instruction; Insulin Resistance; Intervention; Latino; Life; Mediator of activation protein; Metabolic syndrome; Modeling; Non-Insulin-Dependent Diabetes Mellitus; Obesity; Outcome; Preventive Intervention; Process; Public Health; Quality of life; Randomized Controlled Trials; Research; Research Personnel; Risk; Societies; Solutions; Testing; Weight; Youth; base; contextual factors; cost effective; cost effectiveness; diabetes prevention program; efficacy testing; experience; health disparity; improved; innovation; insulin sensitivity; intervention effect; lifestyle intervention; programs; psychosocial; social cognitive theory

PROJECT SUMMARY (See instructions): Obesity-related health disparities represent one of the most significant public health challenges facing our society. In particular, obese Latino adolescents are disproportionately impacted by insulin resistance, psychosocial consequences, and type 2 diabetes but few prevention interventions have been conducted in this vulnerable and underserved group. Therefore, we propose a randomized-controlled trial to test the efficacy of a culturally-grounded, community-based diabetes prevention program to increase insulin sensitivity and weight-specific quality of life in 160 obese Latino adolescents. We will also explore potential mediators and moderators of the intervention's effects and estimate the initial incremental cost-effectiveness of the intervention for increasing insulin sensitivity. The intervention is guided by Social Cognitive Theory and framed within a multilevel ecodevelopmental model to address surrounding contextual factors that are thought to influence health behaviors and health outcomes in obese Latino youth during a critical life period. The project builds upon extant collaborations of a transdisciplinary team of investigators with the community to address critical gaps in how prevention interventions for obese Latino youth are developed, implemented and evaluated. This innovative approach is an essential step in the development of cost-effective, solution oriented programs to improve the health of Latino youth.

项目摘要（请参阅说明）： 与肥胖有关的健康差异是我们社会面临的最重大公共卫生挑战之一。特别是，肥胖的拉丁裔青少年受到胰岛素抵抗，社会心理后果和2型糖尿病的影响不成比例的，但在这个脆弱和服务不足的组中，很少进行预防干预措施。因此，我们提出了一项随机控制的试验，以测试以培养的基于社区的糖尿病预防计划的功效，以提高160名肥胖的拉丁裔青少年的胰岛素敏感性和特定体重的生活质量。我们还将探索潜力 干预效果的介体和主持人，并估算了胰岛素敏感性提高干预措施的初始增量成本效益。干预措施以社会认知理论为指导，并在多层次的生态发展模型中构建，以解决周围的环境因素，这些因素被认为会影响关键生活期间肥胖拉丁裔青年的健康行为和健康状况。 该项目建立在调查人员与社区的跨学科团队的现有合作基础上，以解决如何开发，实施和评估肥胖拉丁裔青年的预防干预措施的关键差距。这种创新的方法是开发具有成本效益的，以解决方案为导向的计划来改善拉丁裔青年健康的重要步骤。