Research Training: Chronic Non-communicable CVDs and Comorbidities in Peru

研究培训：秘鲁的慢性非传染性心血管疾病和合并症

• 批准号: 10308323
• 负责人: Victor G. Davila-Roman
• 金额: $ 25.12万
• 依托单位: WASHINGTON UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-09-01 至 2026-07-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10308323
• 关键词: Address; Area; Awareness; Baltimore; Cardiovascular Diseases; Career Mobility; Chronic; Collaborations; Discipline; Dissemination and Implementation; Doctor of Philosophy; Environmental Exposure; Evidence based intervention; Exposure to; Faculty; Foundations; Funding; German population; Goals; Grant; Health Professional; Healthcare; High Prevalence; Hypertension; Institution; International; Intervention; Leadership; Mentors; National Heart, Lung, and Blood Institute; National Institute of Environmental Health Sciences; National Institute of Neurological Disorders and Stroke; National Institute on Aging; Peru; Peruvian; Policies; Public Health; Research; Research Infrastructure; Research Personnel; Research Project Grants; Research Training; Risk Factors; Scientist; Secure; Stroke; Structure; Training; Training Programs; Training and Infrastructure; Translations; United States National Institutes of Health; Universities; Washington; burden of illness; cardiovascular disorder risk; career; comorbidity; design; global health; implementation science; improved; international center; low and middle-income countries; low socioeconomic status; multidisciplinary; programs; skills; social factors; training opportunity

PROJECT SUMMARY MPIs: de las Fuentes, Lisa; Davila-Roman, Victor G.; Málaga, German; Hartinger, Stella D43 Project Title: “Research Training: Chronic Non-communicable CVDs and Comorbidities in Peru” Project start / end: 9/1/2021-8/31/2026 Chronic cardiovascular disease (CVD) is the leading cause of M&M worldwide and in Peru. In addition to the usual CVD risk factors, social factors such a low socioeconomic status and environmental exposure further contribute to chronic CVD burden. Among non-communicable diseases (NCDs), high prevalence of hypertension with low rates of awareness, treatment and control represent an important health care gap that contributes to CVD burden in Peru. This application for D43 Training Grant represents a collaboration between US investigators (Washington University in St. Louis and Johns Hopkins University in Baltimore) and Peruvian investigators (Universidad Peruana Cayetano Heredia in Lima, Universidad Nacional del Altiplano de Puno, AB PRISMA in Lima and Puno). The D43 training program will leverage existing research projects and infrastructure in Peru to train Peruvian scientists and health professionals in chronic NCDs/CVD. Our group has been successful in securing grant support (i.e., NIH, Gates Foundation); however, the limited number of Peruvian investigators conducting and leading NCD/CVD studies represents a significant barrier to implementing an effective and sustainable NCD/CVD research program. The proposed training program will provide support (tuition, stipend, research funds) for 14 trainees over five years: 8 master’s, 4 PhD, and 2 postdoctoral Peruvian trainees and/or junior faculty. The objectives of this structured program are to develop the research careers of trainees in the areas of chronic CVD, stroke, implementation science, and environmental exposure; to provide mentoring and support by an internationally renowned faculty with multidisciplinary expertise; and to provide opportunities for career advancement and engagement in research projects. The program will provide intensive training opportunities and build capacity in a range of scientific disciplines and skills relevant to achieving research independence. The long-term goal of this program is to build a sustainable and collaborative research-training infrastructure to develop Peruvian research scientists capable of designing and executing interventions addressing unmet healthcare needs, including the translation of evidence-based interventions and the implementation and dissemination of effective policies to improve public health in Peru. This application is responsive to partnering institutions of PAR-18-901 including the NHLBI (HTN/CVD), Fogarty International Center (global health and LMIC), National Institute of Aging (NCDs including CVD/HTN), National Institute of Neurological Disorders and Stroke (stroke), and National Institutes of Environmental Health Sciences (environmental exposure as risk factors for NCDs/CVD). The ultimate goals of this D43 training program are twofold: 1) to equip outstanding junior investigators with the necessary expertise to solve challenging problems presented by the burden of chronic NCDs/CVD in Peru; and 2) to complete a full transition of program administration and leadership from the US to Peruvian MPIs, faculty, and institutions by D43 Year 5.

项目摘要 MPIS：丽莎·德·拉斯·富恩特斯（De Las Fuentes）； Davila-Roman，Victor G。； Málaga，德语；哈丁格，斯特拉 D43项目名称：“研究培训：秘鲁的慢性非传染性CVD和合并症” 项目开始/结束：9/1/2021-8/31/2026 慢性心血管疾病（CVD）是全球M＆M的主要原因。除了 通常的CVD风险因素，社会因素（例如社会经济状况低下和环境暴露） 导致慢性CVD负担。在非通信疾病（NCDS）中，高血压的高患病率 意识率低，治疗和控制率代表了一个重要的医疗保健差距 秘鲁的CVD Burnen。此D43培训赠款的申请代表了我们之间的合作 调查人员（圣路易斯华盛顿大学和巴尔的摩的约翰·霍普金斯大学）和 秘鲁调查人员（佩鲁阿纳大学Cayetano Heredia大学 利马和普诺的Altiplano de Puno，AB Prisma）。 D43培训计划将利用现有的研究 秘鲁的项目和基础设施培训慢性NCD/CVD的秘鲁科学家和卫生专业人员。 我们的小组已成功获得赠款支持（即NIH，盖茨基金会）；但是，有限 进行NCD/CVD研究的秘鲁研究人员的数量代表了 实施有效且可持续的NCD/CVD研究计划。拟议的培训计划将 在五年内为14名学员提供支持（学费，压力，研究基金）：8个硕士学位，4博士学位和2个 博士后秘鲁学员和/或初级教师。该结构化程序的目标是开发 慢性CVD，中风，实施科学和环境领域的受训者的研究职业 接触;为具有多学科的国际知名教师提供心理和支持 专业知识;并为职业发展和参与研究项目提供机会。 计划将提供密集的培训机会，并在一系列科学学科中建立能力 与实现研究独立性相关的技能。该计划的长期目标是建立可持续性 以及协作研究培训基础设施，以开发能够设计的秘鲁研究科学家 并执行解决未满足医疗保健需求的干预措施，包括循证基于证据的翻译 干预措施以及有效政策的实施和传播，以改善秘鲁的公共卫生。 该申请敏感对包括NHLBI（HTN/CVD）的PAR-18-901的合作机构，Fogarty 国立老龄研究所（包括CVD/HTN在内的NCD）国际中心（全球卫生和LMIC），国家 神经系统疾病与中风研究所（中风）和国立环境卫生学院 （环境暴露是NCD/CVD的风险因素）。该D43培训计划的最终目标是 双重：1）为杰出的初级调查人员配备必要的专业知识来解决挑战 秘鲁的慢性NCD/CVD的伯恩（Burnen）带来的问题； 2）完成完全的过渡 D43年级的计划管理和领导层来自美国到秘鲁MPI，教职员工和机构。