Pain and Neurodegenerative Undergraduate Research Experiences: Interacting with community partners to build specialized and enhanced neurologic disease programs for undergraduates.

项目总结 在过去的十年里，由于国会预算削减，美国国立卫生研究院对生物医学研究的资金大幅下降 尽管公共卫生需求日益增长。除了这种削减对生产力的明显影响之外， 研究实验室，这种资金环境可能会阻止本科生在 生物医学研究。这种影响将特别不利于对慢性阻塞性肺疾病的研究和理解 神经疾病，一个日益令人担忧的领域。我们旨在通过支持专业人员来抵消这种可能性 夏季本科生在疼痛和神经退行性疾病方面的研究经验。这样做的理由是 建议通过加强神经系统疾病的本科生研究项目，我们可以开始 建立一个熟练的研究人员管道，以应对日益增长的神经退行性疾病，因为我们的 人口老龄化。这项建议旨在发展并继续实施两项协同生物医学研究 程序。这些新项目，疼痛本科生研究体验(PURE)和 神经退行性本科生研究体验(Nure)，是跨学科和社区- 参与生物医学暑期本科生研究项目。《纯洁与纯真》的目标 暑期计划旨在增加学生对疼痛和疼痛的基本科学的了解和接触 神经退化，更重要的是，通过连接基本的 科学研究，为学生提供与临床研究人员进行现场和非现场互动的机会。12(6%) 计划)每年夏天将招募二年级及以上的学生参加为期10周的纯洁或纯真课程 会议。我们预计将招收各种本科专业的学生，包括生物、化学、 生物化学、物理治疗前、职业前治疗、制药前、神经科学、物理学、计算机 科学和生物医学工程。[我们的目标是通过招收不同类型的学生 在全国范围内，从大型研究型大学、历史上的黑人学院和大学，到拉美裔服务 来自研究水平较低的机构，主要是本科院校。]

PROJECT SUMMARY In the last decade, due to Congressional budget cuts, NIH funding for biomedical research has plummeted despite a growing public health need. Beyond the obvious effect of this reduction on the productivity of research labs, this funding climate likely dissuades undergraduate students from pursuing careers in biomedical research. This effect will be particularly deleterious to the study and understanding of chronic neurologic disease, an area of growing concern. We aim to counteract this possibility by supporting specialized summer undergraduate research experiences in pain and neurodegenerative disease. The rationale for this proposal is that by strengthening undergraduate research programs in neurologic disease, we can begin to build a pipeline of skilled researchers to respond to increasing rates of neurodegenerative diseases as our population ages. This proposal aims to develop and continue to implement two synergistic biomedical research programs. These new programs, the Pain Undergraduate Research Experience (PURE) and Neurodegenerative Undergraduate Research Experience (NURE), are cross-disciplinary and community- engaged biomedical summer undergraduate research programs. The objective of the PURE and NURE summer program is to increase student understanding of and exposure to the underlying science of pain and neurodegeneration, and importantly, to offer a more complete and authentic experience, by bridging basic science research with opportunities for students to interact on- and off-site with clinical researchers. 12 (six per program) rising sophomores and above will be recruited each summer for a 10-week long PURE or NURE session. We anticipate recruiting students from a variety of undergraduate majors including biology, chemistry, biochemistry, pre-physical therapy, pre-occupational therapy, pre-pharmacy, neuroscience, physics, computer science, and biomedical engineering. [We aim to include a diverse population of students by recruiting nationally from large research universities, historically black colleges and universities, Hispanic-serving institutions, and regionally from low research and primarily undergraduate institutions.]