Shared Resource-Functional Genomics and Genome Sequencing Core

共享资源-功能基因组学和基因组测序核心

• 批准号: 10328944
• 负责人: RONALD M EVANS
• 金额: $ 23万
• 依托单位: SALK INSTITUTE FOR BIOLOGICAL STUDIES
• 依托单位国家: 美国
• 财政年份: 1996
• 资助国家: 美国
• 起止时间: 1996-12-31 至 2024-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10328944
• 关键词: Cancer Center; Cancer Center Support Grant; DNA Sequencing Facility; Data; Development; Ensure; Experimental Designs; Future; Genomics; High-Throughput Nucleotide Sequencing; Institutes; Libraries; Methods; Mission; NCI Center for Cancer Research; Preparation; Quality Control; Research; Resource Sharing; Sampling; Services; Technology; Training; cost effective; experimental study; functional genomics; genome sequencing; instrumentation; member; next generation sequencing; novel; sequencing platform; single cell sequencing

Functional Genomics and Genome Sequencing Core Shared Resource - Project Summary/Abstract The mission of the Functional Genomics and Genome Sequencing Core is to facilitate cutting-edge genomics research at the Salk Institute by providing: 1) cost-effective and rapid high-throughput sequencing services, 2) expert assistance in experimental design, and 3) the development of novel methods to enable cutting edge sequencing technologies. In addition, the Core prepares sequencing libraries and performs quality control to ensure that high-quality data are extracted from each experimental sample. In the near future, the Core will acquire and implement a single cell sequencing platform. In support of Cancer Center research endeavors at the Salk, the Core specifically aims to provide: 1) access to state-of-the-art instrumentation for next-generation sequencing projects, 2) assistance with experimental design when Salk Cancer Center members are seeking to perform experiments that involve sequencing technologies, 3) novel methods and strategies for implementing cutting-edge sequencing technologies, 4) preparation and quality control of sequencing libraries, and 5) training services for Cancer Center members in library preparation or other methods required for next- generation sequencing projects.

功能基因组学和基因组测序核心共享资源-项目摘要/摘要 功能基因组学和基因组测序核心的使命是促进尖端基因组学 索尔克研究所的研究提供：1）具有成本效益和快速的高通量测序服务，2） 专家协助实验设计，以及3）开发新方法，使尖端 测序技术。此外，Core还准备测序文库并进行质量控制， 确保从每个实验样本中提取高质量的数据。在不久的将来，核心 获得并实施单细胞测序平台。为了支持癌症中心的研究工作， 在索尔克，核心的具体目标是提供：1）获得国家的最先进的仪器，为下一代 测序项目，2）当索尔克癌症中心成员寻求 进行涉及测序技术的实验，3）用于 实施尖端测序技术，4）测序文库的制备和质量控制， 以及5）为癌症中心成员提供图书馆准备或其他方法的培训服务， 代测序项目。