Molecular Genetics Resource Core

分子遗传学资源核心-综述 分子遗传学资源核心(MGRC)将为宾夕法尼亚大学提供各种服务 华盛顿阿片类药物研究卓越中心。我们将为神经网络提供最先进的病毒载体 电路切割，产生大量基于病毒的CRISPR/Cas9靶向载体用于体内分子电路 分析，并提供对由开发的新型传感器和致动器的病毒传递平台的访问 威斯康星大学的成瘾研究人员。UW MGRC还将为UW成瘾研究人员创造新的小鼠品系 并为研究人员发起的调查提供对现有鼠标系的访问。UW的一项主要条款 MGRC将为研究生、博士后研究员、 和合格的本科生。我们还将为UW的教育和培训提供暑期工作坊 成瘾研究实习生。UW MGRC提供的资源、教育和培训将 促进迅速传播关于阿片类药物分子和遗传基础的前沿研究 并为下一代科学家在物质使用障碍研究方面的职业生涯做好准备。

Molecular Genetics Resource Core – Summary The Molecular Genetics Resource Core (MGRC) will provide a variety of services for the University of Washington Center for Excellence in Opioid Research. We will provide state-of-the-art viral vectors for neural circuit dissection, generate numerous viral-based CRISPR/Cas9 targeting vectors for in vivo molecular circuit analysis, and provide access to platforms for the viral delivery of novel sensors and actuators developed by UW addiction researchers. The UW MGRC will also generate novel mouse lines for UW addiction researchers and provide access to existing mouse lines for researcher initiated investigations. A major provision of the UW MGRC will be hands on training in molecular genetics techniques for graduate students, postdoctoral fellows, and qualified undergraduates. We will also provide a Summer Workshop for the education and training of UW addiction research trainees. Collectively the resources, education, and training provided by the UW MGRC will facilitate the rapid dissemination of cutting-edge research on the molecular and genetic basis of opioid addiction and prepare the next generation of scientists for careers in substance use disorder research.