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Continued Support of an spf Macaca nemestrina breeding colony

Continued Support of an spf Macaca nemestrina breeding colony
继续支持 spf 猕猴繁殖群
批准号:
10399733
负责人:
Eric Kenneth Hutchinson
金额:
$55.46万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2021
资助国家:
美国
项目状态:
已结题
起止时间:
2021-06-01 至 2022-02-28

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中文摘要
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英文摘要
Abstract The aim of this application is to seek bridge funding to maintain the health, well-being, and continued SPF status of the Johns Hopkins pig-tailed macaque colony during the period of no-cost extension, until the award of a successful renewal application. During this period, the JHU colony will continue to provide healthy, behaviorally normal, MHC-characterized, SPF pig-tailed macaques for NIH-funded HIV/AIDS related research. We will continue our plan of expanding the current SPF breeding colony to increase the numbers of females for breeding and juvenile males and females available for sale to NIH- funded HIV/AIDS investigators both within Johns Hopkins University and at other research institutions. We will continue to conduct basic pathogen testing, to include regular tuberculosis skin tests and viral screening to ensure the colony remains SPF for the following viral agents: Cercopithecine herpesvirus 1 (B virus), Simian Immunodeficiency Virus (SIV), Simian Retrovirus (SRV), and Simian T-lymphotrophic Virus (STLV), as well as screening the colony for SARS-CoV-2 infection. We have already undertaken a number of facility and programmatic improvements in response to reviewer feedback on our previous renewal application, as well as expanding the functional capacity of the facility for continued colony growth. With the exception of the caging replacement project, which was funded by the use of previously unspent U42 funds and will be completed prior to the no-cost extension period, these improvements are funded internally by JHU and will continue apace during this bridge period.
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Expansion and modification of animal housing and support spaces to increase production of the NIH U42 supported pigtailed macaque colony at Johns Hopkins University
  • 批准号:
    10592753
  • 项目类别:
  • 资助金额:
    $550.02万
  • 财政年份:
    2022
  • 负责人:
    Eric Kenneth Hutchinson
  • 依托单位:
Husbandry Core
  • 批准号:
    10403107
  • 项目类别:
  • 资助金额:
    $86.08万
  • 财政年份:
    2006
  • 负责人:
    Eric Kenneth Hutchinson
  • 依托单位:
Husbandry Core
  • 批准号:
    10576953
  • 项目类别:
  • 资助金额:
    $86.08万
  • 财政年份:
    2006
  • 负责人:
    Eric Kenneth Hutchinson
  • 依托单位:
Viral Testing Core
  • 批准号:
    10576957
  • 项目类别:
  • 资助金额:
    $11.58万
  • 财政年份:
    2006
  • 负责人:
    Eric Kenneth Hutchinson
  • 依托单位:
海外基金