TBD
待定
基本信息
- 批准号:10399838
- 负责人:
- 金额:$ 25万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2018
- 资助国家:美国
- 起止时间:2018-07-01 至 2023-06-30
- 项目状态:已结题
- 来源:
- 关键词:AcuteAnimal ModelAnimalsAreaArtsAwardBasic ScienceBiomedical ResearchBlood VesselsCardiometabolic DiseaseCardiovascular DiseasesCardiovascular systemCause of DeathCenters of Research ExcellenceClinicalComplementCore FacilityCountryDataDevelopmentDiabetes MellitusDisciplineDiseaseEndocrineEnsureEnvironmentEnvironmental ExposureEpidemicEventExcess MortalityFacultyFlow CytometryFosteringFoundationsFundingGoalsGrantGrowthHealthHumanImageIndividualInflammationInfrastructureInstitutionInsulin ResistanceInterdisciplinary StudyInvestigationLaboratoriesLeadLearningMedicineMentorsMentorshipMetabolicMetabolismMolecularMyocardial InfarctionNon-Insulin-Dependent Diabetes MellitusObesityPathologyPhasePhenotypePhysiologyPilot ProjectsPostdoctoral FellowPublic Health SchoolsResearchResearch InfrastructureResearch PersonnelResearch Project GrantsResearch SupportResearch TrainingResourcesRisk FactorsScienceSeedsServicesSolidStrokeTherapeuticTrainingTranslational ResearchUnited States National Institutes of HealthUniversitiesVascular DiseasesWorkbasecardiovascular disorder riskcareercareer developmentclinical investigationdiabeticgraduate studentinnovationinterdisciplinary approachinterestmembermultidisciplinarynovelpreventprogramsrecruitstem cell biologysudden cardiac death
项目摘要
ABSTRACT
This application is to support Phase III of the COBRE-supported Diabetes and Obesity Center at
the University of Louisville. The Center was established in 2008, with the central objective of
supporting molecular, cellular, experimental, translational and clinical investigations into the
cardiovascular causes and consequences of diabetes and obesity. During Phase I and II, the
Center underwent phenomenal growth. It has facilitated the career development of junior
investigators, provided core support to investigators involved in diabetes, obesity and
cardiovascular research, and has provided training and mentorship to graduate students and
post-doctoral fellows. The goal in Phase III is to provide sustainable core support to Center
investigators and strengthen diabetes and obesity research at the institution; to maintain and
enhance state-of-the-art infrastructure, foster research and support basic and translational
research within the thematic focus of the Center. In Phase III, the Center will support 5 Cores –
Core A: An Administrative Core, Core B: Flow Cytometry Core, Core C, Pathology and Bioanlytics
Core, Core D: Animal Models and Phenotyping Core, and Core E: Imaging and Physiology Core.
The Center will also support a Pilot Project Program to stimulate new research by providing seed
funding to promising projects that could obtain extramular funding. The Center provides unique
opportunities for research in the areas of cardiovascular metabolism, inflammation and
cardiometabolic disease, stem cell biology, and environmental determinants of cardiometabolic
disease. A dynamic, self-sustaining Diabetes and Obesity Center at the University of Louisville
will not only provide fertile ground for innovative studies in the area of diabetes, obesity, and
cardiovascular research, but it will enable the institution to become an enduring hub of learning,
mentoring, training, and fostering academic excellence.
摘要
此应用程序是为了支持COBRE-supported糖尿病和肥胖中心的第三阶段,
路易斯维尔大学该中心成立于2008年,中心目标是
支持分子、细胞、实验、转化和临床研究,
糖尿病和肥胖的心血管原因和后果。在第一和第二阶段,
中心经历了惊人的增长。它促进了初级职业发展,
研究人员,为参与糖尿病,肥胖和
心血管研究,并为研究生提供培训和指导,
博士后第三阶段的目标是为中心提供可持续的核心支持。
研究人员和加强糖尿病和肥胖症的研究在该机构;保持和
加强最先进的基础设施,促进研究,支持基础和转化
研究中心的主题重点。在第三阶段,该中心将支持5个核心-
核心A:管理核心,核心B:流式细胞术核心,核心C,病理学和生物分析学
核心,核心D:动物模型和表型核心,以及核心E:成像和生理学核心。
该中心还将支持试点项目计划,通过提供种子来刺激新研究
资助有希望获得额外资助的项目。该中心提供独特的
在心血管代谢,炎症和
心脏代谢疾病、干细胞生物学和心脏代谢疾病的环境决定因素
疾病路易斯维尔大学的一个充满活力、自我维持的糖尿病和肥胖中心
不仅将为糖尿病、肥胖症和肥胖症领域的创新研究提供肥沃的土壤,
心血管研究,但它将使该机构成为一个持久的学习中心,
指导、培训和促进学术卓越。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Steven P Jones其他文献
Relation of hepatic steatosis to atherogenic dyslipidemia.
肝脂肪变性与动脉粥样硬化性血脂异常的关系。
- DOI:
10.1016/j.amjcard.2013.08.001 - 发表时间:
2013 - 期刊:
- 影响因子:0
- 作者:
S. Makadia;M. Blaha;Tanya E Keenan;C. Ndumele;Steven P Jones;A. DeFilippis;S. Martin;P. Kohli;R. Conceição;J. Carvalho;K. Nasir;R. Blumenthal;R. Santos - 通讯作者:
R. Santos
Myocardial Reperfusion Injury: Insights Gained from Gene-Targeted Mice.
心肌再灌注损伤:从基因靶向小鼠中获得的见解。
- DOI:
- 发表时间:
2000 - 期刊:
- 影响因子:0
- 作者:
Steven P Jones;D. Lefer - 通讯作者:
D. Lefer
Leukocyte-Endothelial Interactions Following Myocardial Ischemia
心肌缺血后白细胞与内皮细胞的相互作用
- DOI:
- 发表时间:
2003 - 期刊:
- 影响因子:0
- 作者:
D. Lefer;Steven P Jones - 通讯作者:
Steven P Jones
PSS144 - Impact of Type 2 Diabetes on Cardiac Stem Cell Phenotype and Therapeutic Efficacy
- DOI:
10.1016/j.freeradbiomed.2013.10.563 - 发表时间:
2013-11-01 - 期刊:
- 影响因子:
- 作者:
Bradford G Hill;Timothy D Cummins;Yiru Guo;Junjie Du;James McCracken;Joshua K Salabei;Petra Haberzettl;Candice R Holden;Steven P Jones;Qianhong Li;Roberto Bolli;Aruni Bhatnagar - 通讯作者:
Aruni Bhatnagar
PSS172 - Regulation of the Hyperproliferative Vascular SmoothMuscle Phenotype by Mitochondrial Fission
- DOI:
10.1016/j.freeradbiomed.2013.10.591 - 发表时间:
2013-11-01 - 期刊:
- 影响因子:
- 作者:
Joshua K Salabei;Andrew a Gibb;Steven P Jones;Aruni Bhatnagar;Bradford G Hill - 通讯作者:
Bradford G Hill
Steven P Jones的其他文献
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{{ truncateString('Steven P Jones', 18)}}的其他基金
Center for Excellence in Diabetes and Obesity Research
糖尿病和肥胖研究卓越中心
- 批准号:
10452732 - 财政年份:2018
- 资助金额:
$ 25万 - 项目类别:
Supplement to Center for Excellence in Diabetes and Obesity Research: Implementing Biomechanics Instrumentation in the Diabetes and Obesity Center
糖尿病和肥胖研究卓越中心的补充:在糖尿病和肥胖中心实施生物力学仪器
- 批准号:
10582129 - 财政年份:2018
- 资助金额:
$ 25万 - 项目类别:
Center for Excellence in Diabetes and Obesity Research
糖尿病和肥胖研究卓越中心
- 批准号:
10208898 - 财政年份:2018
- 资助金额:
$ 25万 - 项目类别:
CENTER OF EXCELLENCE IN DIABETES AND OBESITY RESEARCH: CORE C
糖尿病和肥胖研究卓越中心:CORE C
- 批准号:
8360411 - 财政年份:2011
- 资助金额:
$ 25万 - 项目类别:
CENTER OF EXCELLENCE IN DIABETES AND OBESITY RESEARCH: CORE C
糖尿病和肥胖研究卓越中心:CORE C
- 批准号:
8168206 - 财政年份:2010
- 资助金额:
$ 25万 - 项目类别:
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