ABCD-USA Consortium: Coordinating Center

项目总结 在此，我们请求资金，以继续在第一个供资期间开始的工作，以实现以下扩大的目标 这扩大了ABCD研究的原始范围： ·解决有关性别认同、性认同和性健康可能发挥的作用的重要问题 在修改ABCD中衡量的重要健康、精神健康和其他结果方面。 ·增强ABCD回答有关青少年性健康的重要问题的能力， 特别是关于性别和性行为的规范轨迹。 为了实现这些新目标，ABCD财团必须对研究的设计进行修改， 增加，有时是开发新的测量方法，在发育敏感和 参与者的发育知情方式、性别认同、性认同和性健康 ABCD研究。 还需要对多个领域的评估进行其他修改，以确保研究能够 在ABCD研究中，充分评估性和性别少数青少年可能增加的风险； 以前在这一青年群体中报告的可能导致健康差距的风险。 自从获得这个项目的补充资金以来，一个新的性别认同和性健康(GISH) 工作组成立，成员来自ABCD调查员小组、美国国立卫生研究院和疾病预防控制中心。就其本身而言 此工作组的职能类似于zu chu zu中的其他专家工作组，负责一组特定的 与CC、DAIRC和其他咨询和监督小组在 财团。在提案中，我们描述了CC-DAIRC-工作组交互所需的生成、 评估、整合、监控、更新、解释和共享ABCD研究中收集的所有数据。 需要继续提供资金，以继续修订ABCD的性别评估，确保青年 接受和有效拟议的修订，并抵消以下中心和地点的额外费用 扩展他们的评估流程，将这组协议要素包括在当前ABCD研究中 设计。如上所述，GISH工作组依赖于来自CC和 DAIRC将实现这些目标。

PROJECT SUMMARY Here we request funds to continue work begun in the first funding period to pursue the following augmented aims that expand the original scope of the ABCD study: · Address important questions about the possible roles of gender identity, sexual identity, and sexual health in modifying important health, mental health, and other outcomes measured in ABCD. · Enhance the capacity within ABCD to answer important questions about sexual health in adolescents, particularly about normative trajectories of gender and sexuality. To accomplish these new aims, the ABCD consortium must make modifications to the design of the study, adding, and sometimes developing, new methods for measuring, in a developmentally sensitive and developmentally informed manner, the gender identity, sexual identity, and sexual health of participants in the ABCD study. Other modifications of the assessments across multiple domains are needed to ensure that the study can adequately assess risks that may be increased in sexual and gender minority teens in the ABCD study; risks that may contribute to health disparities previously reported in this group of youth. Since receiving supplemental funding for this project, a new Gender Identity and Sexual Health (GISH) workgroup was established, with membership from the ABCD investigator group, NIH, and CDC. As such this workgroup functions like other expert workgroups in ABCD with responsibility for a specific set of interactions with the CC, DAIRC, and other advisory and oversight groups within and external to the consortium. In the proposal, we describe the CC-DAIRC-workgroup interactions required to generate, evaluate, integrate, monitor, update, interpret, and share all data collected within the ABCD Study. Continued funding is needed to continue revising gender assessments in ABCD, ensuring youth acceptance and validity of proposed revisions, and to offset additional costs to the centers and sites of expanding their assessment processes to include this set of protocol elements within the current ABCD study design. As described above, the GISH workgroup relies on integrated support from both the CC and the DAIRC to accomplish these aims.