ABCD-USA Consortium: Coordinating Center

项目摘要 在此，我们请求提供资金，继续开展第一个供资期开始的工作，以实现以下扩大的目标 扩展了ABCD研究的原始范围： ·解决有关性别认同，性认同和性健康的可能作用的重要问题 在修改重要的健康，心理健康，和其他成果衡量ABCD。 ·提高ABCD回答有关青少年性健康的重要问题的能力， 特别是关于性别和性行为的规范轨迹。 为了实现这些新的目标，ABCD联盟必须修改研究的设计， 增加，有时开发新的方法来衡量，在一个发展敏感， 发展知情的方式，性别认同，性身份，和性健康的参与者， ABCD研究 需要对多个领域的评估进行其他修改，以确保研究能够 充分评估ABCD研究中性和性别少数青少年可能增加的风险; 这些风险可能导致先前报告的这一青年群体的健康差异。 自从获得该项目的补充资金以来，新的性别认同和性健康（GISH） ABCD研究小组成立，成员来自ABCD研究小组、NIH和CDC。因此 此专家工作组的功能与ABCD中的其他专家工作组类似，负责一组特定的 与CC，DAIRC以及内部和外部的其他咨询和监督小组的互动 财团在该提案中，我们描述了CC-DAIRC-ESTA交互所需的生成， 评估、整合、监控、更新、解释和共享ABCD研究中收集的所有数据。 需要继续提供资金，以继续修订ABCD中的性别评估， 建议修订的接受和有效性，并抵消中心和研究中心的额外费用， 扩展他们的评估过程，将这套方案要素纳入当前ABCD研究 设计如上所述，高收入者地位保障小组的工作依靠协调委员会和 DAIRC将努力实现这些目标。

PROJECT SUMMARY Here we request funds to continue work begun in the first funding period to pursue the following augmented aims that expand the original scope of the ABCD study: · Address important questions about the possible roles of gender identity, sexual identity, and sexual health in modifying important health, mental health, and other outcomes measured in ABCD. · Enhance the capacity within ABCD to answer important questions about sexual health in adolescents, particularly about normative trajectories of gender and sexuality. To accomplish these new aims, the ABCD consortium must make modifications to the design of the study, adding, and sometimes developing, new methods for measuring, in a developmentally sensitive and developmentally informed manner, the gender identity, sexual identity, and sexual health of participants in the ABCD study. Other modifications of the assessments across multiple domains are needed to ensure that the study can adequately assess risks that may be increased in sexual and gender minority teens in the ABCD study; risks that may contribute to health disparities previously reported in this group of youth. Since receiving supplemental funding for this project, a new Gender Identity and Sexual Health (GISH) workgroup was established, with membership from the ABCD investigator group, NIH, and CDC. As such this workgroup functions like other expert workgroups in ABCD with responsibility for a specific set of interactions with the CC, DAIRC, and other advisory and oversight groups within and external to the consortium. In the proposal, we describe the CC-DAIRC-workgroup interactions required to generate, evaluate, integrate, monitor, update, interpret, and share all data collected within the ABCD Study. Continued funding is needed to continue revising gender assessments in ABCD, ensuring youth acceptance and validity of proposed revisions, and to offset additional costs to the centers and sites of expanding their assessment processes to include this set of protocol elements within the current ABCD study design. As described above, the GISH workgroup relies on integrated support from both the CC and the DAIRC to accomplish these aims.