ABCD-USA Consortium: Coordinating Center
ABCD-USA Consortium: Coordinating Center
批准号:
10755471
负责人:
SANDRA A BROWN
金额:
$76.5万
依托单位国家:
美国
项目类别:
财政年份:
2015
资助国家:
美国
项目状态:
未结题
起止时间:
2015-09-30 至 2027-03-31
关键词:
AddressAdolescenceAdolescentAreaBehaviorBiological MarkersBlood PressureBrainChild NutritionCholesterolCollectionDataData CollectionData Coordinating CenterData ElementDevelopmentEnsureEnvironmental ExposureFerritinFutureGlycosylated hemoglobin AGoalsHealthHealth behaviorHeart RateHematologyHigh Density LipoproteinsInterventionIronLife StyleLinkMonitorNational Heart, Lung, and Blood InstituteOutcomePhysiologicalPopulationPopulation HeterogeneityProtocols documentationRecommendationResearchResearch PersonnelSample SizeSiteTimeTrainingWorkYouthadolescent healthcardiometabolismcognitive developmentcognitive functioncohortdata repositorydesignhealth assessmentopen dataphysical conditioningsocialsociodemographics
中文摘要
项目总结/摘要
不良的心脏代谢特征和健康行为通常开始出现在青春期。以下
NHLBI补充申请概述了青少年大脑认知发展(ABCD)的建议
本研究旨在通过有关心脏代谢和
在这段时间里,年轻人的血液健康。这些额外的数据将包括心率和血液
血压、总胆固醇、HDL、HbA 1C、CBC、铁蛋白、铁和儿童营养。这些数据将提供关键
有关参与ABCD的青少年生理健康的信息,并且可以与其他数据相关
对认知功能和大脑发育的影响此外,研究这些之间的关系
生理结果、社会和环境暴露以及生活方式行为可能有助于
估计其对青少年健康的影响,并确定干预目标。ABCD的大样本量
(N= 11,880)和多样化的人群也将使研究人员能够对以下问题有更细致的了解:
这些关系,因为它们属于不同的社会人口。要收集的数据元素
将由ABCD身体健康评估工作组与NHLBI的输入进行监督。
该项目还将增加具有这些领域专业知识的ABCD调查员,以监督研究的这些方面
并确保科学地整合针对几个关键问题的分析。这组调查人员将
加入身体健康评估工作组,审查所收集数据的质量,
关于未来数据收集浪潮的建议。协调中心的数据
管理小组(DAIRC)将协助收集和监测数据。他们还将与该网站合作
在21个地点中的每一个地点都有监测员和研究协调员/助理,以确保他们接受培训
需要忠实和准确地执行所设计的协议。总体而言,作为
该补充将有助于开放科学ABCD数据库,使研究人员能够更好地
了解生理生物标志物,认知功能和大脑发育之间的联系。
英文摘要
PROJECT SUMMARY/ABSTRACT
Adverse cardiometabolic profiles and health behaviors often begin to emerge in adolescence. The following
NHLBI Supplement Application outlines the proposal by the Adolescent Brain Cognitive Development (ABCD)
Study to augment the current data being collected on this cohort with information about the cardiometabolic and
hematologic health of youth during this time period. This additional data will include heart rate and blood
pressure, total cholesterol, HDL, HbA1C, CBC, ferritin, iron, and child nutrition. These data will provide key
information regarding the physiologic health of youth participating in ABCD and can be correlated with other data
on cognitive functioning and brain development. Furthermore, examining the relationship between these
physiologic outcomes and social and environmental exposures as well as lifestyle behaviors may help to
estimate their impact on adolescent health and identify targets for intervention. ABCD’s large sample size
(N=11,880) and diverse population will also enable researchers to develop a more nuanced understanding of
these relationships as they pertain to different sociodemographic populations. The data elements to be collected
in this supplement will be overseen by the ABCD Physical Health Assessment Workgroup with input from NHLBI.
The project will also add ABCD investigators with expertise in these areas to oversee these aspects of the study
and ensure scientific integration of analyses addressing several key questions. This group of investigators will
join the Physical Health Assessment Workgroup and review the quality of the data collected and make
recommendations regarding the collection of future waves of data collection. The Coordinating Center’s data
management group (DAIRC) will assist with capturing and monitoring the data. They will also work with the site
monitors and research coordinators/assistants at each of the 21 sites to ensure that they receive the training
needed to faithfully and accurately implement the designed protocols. Overall, the information gained as part of
the supplement will contribute to the open science ABCD data repository, enabling researchers to better
understand the connections between physiologic biomarkers, cognitive function, and brain development.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
National Consortium on Alcohol and NeuroDevelopment in Adolescence (NCANDA): Administrative Resource
-
批准号:10888826
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项目类别:
-
资助金额:$3.95万
-
财政年份:2023
-
负责人:SANDRA A BROWN
-
依托单位:
ABCD-USA Consortium: Coordinating Center
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批准号:10402051
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项目类别:
-
资助金额:$20.0万
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财政年份:2021
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负责人:SANDRA A BROWN
-
依托单位:
ABCD-USA Consortium: Coordinating Center
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批准号:10209550
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项目类别:
-
资助金额:$65.0万
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财政年份:2020
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负责人:SANDRA A BROWN
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依托单位:
ABCD-USA Consortium: Coordinating Center
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批准号:10307028
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项目类别:
-
资助金额:$65.41万
-
财政年份:2015
-
负责人:SANDRA A BROWN
-
依托单位:
ABCD-USA Consortium: Coordinating Center
-
批准号:9982004
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项目类别:
-
资助金额:$281.88万
-
财政年份:2015
-
负责人:SANDRA A BROWN
-
依托单位:
ABCD-USA Consortium: Coordinating Center
-
批准号:10613765
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项目类别:
-
资助金额:$20.0万
-
财政年份:2015
-
负责人:SANDRA A BROWN
-
依托单位:
ABCD-USA Consortium: Coordinating Center
-
批准号:10173134
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项目类别:
-
资助金额:$20.0万
-
财政年份:2015
-
负责人:SANDRA A BROWN
-
依托单位:
ABCD-USA Consortium: Coordinating Center
-
批准号:10755470
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项目类别:
-
资助金额:$20.0万
-
财政年份:2015
-
负责人:SANDRA A BROWN
-
依托单位:
ABCD-USA Consortium: Coordinating Center
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批准号:10614785
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项目类别:
-
资助金额:$40.0万
-
财政年份:2015
-
负责人:SANDRA A BROWN
-
依托单位:
ABCD-USA Consortium: Coordinating Center
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批准号:10817396
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项目类别:
-
资助金额:$20.0万
-
财政年份:2015
-
负责人:SANDRA A BROWN
-
依托单位:
ABCD-USA Consortium: Coordinating Center
-
批准号:9054658
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项目类别:
-
资助金额:$189.98万
-
财政年份:2015
-
负责人:SANDRA A BROWN
-
依托单位:
ABCD-USA Consortium: Coordinating Center
-
批准号:9340916
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项目类别:
-
资助金额:$50.0万
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财政年份:2015
-
负责人:SANDRA A BROWN
-
依托单位:
ABCD-USA Consortium: Coordinating Center
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批准号:10596559
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项目类别:
-
资助金额:$317.97万
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财政年份:2015
-
负责人:SANDRA A BROWN
-
依托单位:
ABCD-USA Consortium: Coordinating Center
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批准号:10393571
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项目类别:
-
资助金额:$354.4万
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财政年份:2015
-
负责人:SANDRA A BROWN
-
依托单位:
ABCD-USA Consortium: Coordinating Center
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批准号:9150612
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项目类别:
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资助金额:$315.38万
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财政年份:2015
-
负责人:SANDRA A BROWN
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依托单位:
National Consortium on Alcohol and NeuroDevelopment in Adolescence: Admin
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批准号:8539733
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项目类别:
-
资助金额:$50.4万
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财政年份:2012
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负责人:SANDRA A BROWN
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依托单位:
National Consortium on Alcohol and Neurodevelopment in Adolescence: Admin
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批准号:10206835
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项目类别:
-
资助金额:$4.98万
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财政年份:2012
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负责人:SANDRA A BROWN
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依托单位:
National Consortium on Alcohol and Neurodevelopment in Adolescence: Admin
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批准号:10187462
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项目类别:
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资助金额:$47.49万
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财政年份:2012
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负责人:SANDRA A BROWN
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依托单位:
National Consortium on Alcohol and NeuroDevelopment in Adolescence: Admin
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批准号:8877379
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项目类别:
-
资助金额:$51.22万
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财政年份:2012
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负责人:SANDRA A BROWN
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依托单位:
National Consortium on Alcohol and NeuroDevelopment in Adolescence: Admin
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批准号:8413208
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项目类别:
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资助金额:$57.29万
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财政年份:2012
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负责人:SANDRA A BROWN
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依托单位:
海外基金