Novel Caging and Equipment to Enhance Social Interaction and Animal Wellbeing in U42 SPF9 Rhesus Macaques.
新型笼具和设备可增强 U42 SPF9 恒河猴的社交互动和动物福祉。
基本信息
- 批准号:10404873
- 负责人:
- 金额:$ 49.98万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2016
- 资助国家:美国
- 起止时间:2016-08-01 至 2024-07-31
- 项目状态:已结题
- 来源:
- 关键词:AIDS vaccine developmentAIDS-Related Opportunistic InfectionsAcquired Immunodeficiency SyndromeAnimal HousingAnimal WelfareAnimalsAreaAttentionAwardBreedingClinicCustomDevelopmentDevicesEquipmentFemaleFundingGoalsHealthHealth SciencesHeightHousingInfantInfrastructureLymphocryptovirusMacacaMacaca mulattaOregonParentsPersonal SatisfactionPhasePopulationPrimatesProblem behaviorProceduresProductionProductivityRequest for ApplicationsResearchResourcesShelter facilitySocial InteractionSocial supportSocializationStructureSupport GroupsSystemUniversitiesVaccine ResearchViralZoonosesanimal breedingdesignenzooticimprovedinnovationnoveloffspringpreventrecruitresearch and developmentrisk minimizationsocialsquare foottransmission processvector vaccinewelfare
项目摘要
PROJECT SUMMARY
The Oregon National Primate Research Center (ONPRC) Expanded SPF (ESPF) Rhesus Macaque Breeding
Colony is a highly specialized breeding colony that provides unique and essential macaques with an expanded
SPF definition for AIDS research. This colony is critical for AIDS-related opportunistic infection research and
vaccine vector development using opportunistic viral agents as vaccine vectors. In order to provide a sufficient
number of appropriate animals, the breeding colony must produce 30 surplus animals annually. Concurrently, it
is necessary to isolate lymphocryptovirus (LCV) free animals and re-derive LCV-free offspring from LCV
seroconverted females in the colony and recruit additional LCV-free infants from Center's conventional SPF
colony. A critical shortage of appropriate ESPF social housing severely constrain both our efforts to increase
the size of the breeding colony to meet project demand and our endeavors to eliminate LCV from the colony.
The application proposes to purchase novel caging and a tunnel to increase the colonies infrastructure for
housing multiple cage-housed animals in the ESPF barrier housing facility. Enhancing social housing
opportunities will benefit animals with existing behavioral problems, provide better developmental trajectories
for infants recruited to the colony, and promote positive animal welfare and health, all while providing an
avenue for ESPF population expansion to keep pace with demand. The application also proposes to purchase
a storage shed for storing enrichment devices and animals transfer boxes. These items are dedicated for the
exclusive support of ESPF macaques to minimize the risk of inadvertently compromising the animals ESPF
status.
项目总结
项目成果
期刊论文数量(0)
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会议论文数量(0)
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Michael K Axthelm其他文献
Michael K Axthelm的其他文献
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{{ truncateString('Michael K Axthelm', 18)}}的其他基金
Expanded SPF Rhesus Macaque Breeding Colony for AIDS Research
扩大 SPF 恒河猴繁殖群以进行艾滋病研究
- 批准号:
10457474 - 财政年份:2016
- 资助金额:
$ 49.98万 - 项目类别:
Expanded SPF Rhesus Macaque Breeding Colony for AIDS Research
扩大 SPF 恒河猴繁殖群以进行艾滋病研究
- 批准号:
9765428 - 财政年份:2016
- 资助金额:
$ 49.98万 - 项目类别:
Expanded SPF Rhesus Macaque Breeding Colony for AIDS Research
扩大 SPF 恒河猴繁殖群以进行艾滋病研究
- 批准号:
9536982 - 财政年份:2016
- 资助金额:
$ 49.98万 - 项目类别:
Expanded SPF Rhesus Macaque Breeding Colony for AIDS Research
扩大 SPF 恒河猴繁殖群以进行艾滋病研究
- 批准号:
10014300 - 财政年份:2016
- 资助金额:
$ 49.98万 - 项目类别:
Expanded SPF Rhesus Macaque Breeding Colony for AIDS Research
扩大 SPF 恒河猴繁殖群以进行艾滋病研究
- 批准号:
9204170 - 财政年份:2016
- 资助金额:
$ 49.98万 - 项目类别:
Phase 2 Enhancement of Outdoor Group Housing for U42 SPF 9 Rhesus Macaques
U42 SPF 9 恒河猴户外群舍第二期强化工程
- 批准号:
10360780 - 财政年份:2016
- 资助金额:
$ 49.98万 - 项目类别:
Expanded SPF Rhesus Macaque Breeding Colony for AIDS Research
扩大 SPF 恒河猴繁殖群以进行艾滋病研究
- 批准号:
10338457 - 财政年份:2016
- 资助金额:
$ 49.98万 - 项目类别:
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