UCSD Research Training Program for Veterinarians

项目概要/摘要 目前需要在基础和转化研究方面受过培训的有才华的兽医科学家， “一个健康”的原则，以发现下一代医学进步， 人类的健康。这一申请延长机构T32赠款寻求资金，以扩大我们的努力， 一个优秀的计划，兽医获得知识和技能，在基础科学，比较 医学和转化研究，以开发和应用人类疾病模型， 改善人类健康。我们的培训计划的具体目标是培养DVM的发展 研究人员在生物医学研究的广泛领域的期望，这些人将继续 成为学术机构或行业的独立调查员。这将通过以下方式实现： 以下具体目标：目标1：确定来自全国各地的申请人的多样化和合格的人才库; 目标2：提供一个鼓舞人心的教学计划，是针对每个申请人的学习议程;目标3： 使学员熟悉与以下方面相关的基础、计算和/或转化研究的持续方法： 目标4：指导受训者设计、执行、评价和介绍 实验导致原创性研究，并为学员提供独立职业所需的技能， 学者。通过该计划，学员将获得知识和技术技能，以充分了解和 评估人类疾病的发病机制以及人类疾病的动物模型， 微生物学、免疫学、计算研究和比较生物学方面的教学课程和应用培训 药学员将能够从一群成功的科学家那里找到导师，他们致力于 研究训练。导师/论文顾问由经验丰富的导师组成， 微生物学、免疫学、癌症、神经生物学、进化、生物信息学的转化研究项目 和比较医学，其中包括一个兽医干部与研究生的既定记录， DVM毕业生的培训和指导。他们的研究计划利用协作和多学科 采用细胞生物学、微生物学、免疫学、系统生物学 生物信息学和比较病理学。通过观察多个部门的强大的互动程序， 在加州大学圣地亚哥分校和整个研究界在圣地亚哥，学员将有一个杰出的 有机会追求成功的专业发展议程。该培训计划将 由UCSD兽医科学和比较医学中心相关的教师管理。 作为这个培训计划的结果，学员将获得一个全面的了解假设为基础的 研究并获得学术界富有成效的职业所需的知识和技能， 培养小鼠病理生物学和比较医学方面熟练科学家的国家需求 与人类健康有关。

PROJECT SUMMARY/ABSTRACT There is an existing need for talented veterinary scientists trained in basic and translational research who apply the principles of “One Health” to discover the next generation of advances in medicine for the improvement of health in humans. This application to renew an institutional T32 grant seeks funds to extend our efforts to build an outstanding program for veterinarians to acquire the knowledge and skills in basic science, comparative medicine and translational research in order to develop and apply models of human disease for the purpose of improving human health. The specific goal of our Training Program is to nurture the development of DVM investigators in the broad field of biomedical research with the expectation that these individuals will go on to become independent investigators at academic institutions or industry. This will be achieved by pursing the following Specific Aims: Aim 1: Identify a diverse and well-qualified pool of applicants from across the country; Aim 2: Provide an inspiring didactic program that is tailored to each applicants learning agenda; Aim 3: Acquaint trainees with the ongoing approaches for basic, computational and/or translational research related to human disease; Aim 4: Mentor the trainees in the design, execution, evaluation and presentation of experiments leading to original research and giving the trainees the skills required for independent careers in academics. Through this program, trainees will gain knowledge and technical skills to fully understand and evaluate the pathogenesis of disease in humans as well as animal models of human disease through both didactic coursework and applied training in microbiology, immunology, computational studies and comparative medicine. Trainees will be able to find mentorship from a successful group of scientists who are dedicated to research training. The mentors/thesis advisors are comprised of experienced preceptors from basic and translational research programs in microbiology, immunology, cancer, neurobiology, evolution, bioinformatics and comparative medicine that include a cadre of veterinarians with an established record in post-graduate training and mentorship of DVM graduates. Their research programs utilize collaborative and multi-disciplinary approaches employing state-of-the-art techniques in cell biology, microbiology, immunology, systems biology, bioinformatics and comparative pathology. By observing strong, interactive programs in multiple departments at UCSD and throughout the research community in San Diego, the trainees will have an outstanding opportunity to pursue an agenda for successful professional development. This training program will be administered by faculty associated with the UCSD Center for Veterinary Sciences and Comparative Medicine. As a result of this training program, trainees will gain a comprehensive understanding of hypothesis-based research and gain knowledge and skills required for productive careers in academics that will address the national needs for the development of skilled scientists in mouse pathobiology and comparative medicine relevant to human health.