UCSD Research Training Program for Veterinarians

项目摘要/摘要 现有的需求是受过基础和翻译研究培训的有才华的兽医科学家 用“一个健康”的原则发现下一代医学的进步，以改善 人类的健康。这项续签机构T32赠款的申请寻求资金，以延长我们的努力，以建立 兽医获取基础科学知识和技能的优秀计划，比较 医学和转化研究，以开发和应用人类疾病模型，目的是 改善人类健康。我们的培训计划的具体目标是培育DVM的发展 生物医学研究的广泛领域的研究人员，期望这些人将继续 成为学术机构或行业的独立调查人员。这将通过以下方式实现： 以下是具体目标：目标1：从全国范围内确定多样化和合格的申请者群体； 目标2：为每个申请者量身定做一个鼓舞人心的教学计划；目标3： 使受训人员熟悉正在进行的基础、计算和/或翻译研究方法 人类疾病；目标4：指导受训人员设计、执行、评估和介绍 引导原创研究的实验，并为受训人员提供独立职业所需的技能 学者。通过这项计划，学员将获得知识和技术技能，以充分了解和 评估人类疾病的发病机制以及人类疾病的动物模型 微生物学、免疫学、计算研究和比较方面的教学课程和应用培训 医药。学员将能够从一群成功的科学家那里找到导师，他们致力于 研究训练。导师/论文导师由来自Basic和 微生物学、免疫学、癌症、神经生物学、进化论、生物信息学的翻译研究项目 以及比较医学，其中包括一批有研究生毕业记录的兽医干部 DVM毕业生的培训和指导。他们的研究项目利用协作和多学科 运用细胞生物学、微生物学、免疫学、系统生物学、 生物信息学和比较病理学。通过在多个部门观察强大的互动性计划 在加州大学圣地亚哥分校和整个圣地亚哥的研究社区，受训人员将拥有出色的 有机会追求成功的职业发展议程。这一培训计划将是 由与加州大学圣迭戈分校兽医科学和比较医学中心有关的教员管理。 作为培训计划的结果，学员将全面了解基于假设的 研究并获得在学术界从事生产性职业所需的知识和技能，这些知识和技能将解决 国家需要培养熟练的小鼠病理生物学和比较医学科学家 与人类健康相关。

PROJECT SUMMARY/ABSTRACT There is an existing need for talented veterinary scientists trained in basic and translational research who apply the principles of “One Health” to discover the next generation of advances in medicine for the improvement of health in humans. This application to renew an institutional T32 grant seeks funds to extend our efforts to build an outstanding program for veterinarians to acquire the knowledge and skills in basic science, comparative medicine and translational research in order to develop and apply models of human disease for the purpose of improving human health. The specific goal of our Training Program is to nurture the development of DVM investigators in the broad field of biomedical research with the expectation that these individuals will go on to become independent investigators at academic institutions or industry. This will be achieved by pursing the following Specific Aims: Aim 1: Identify a diverse and well-qualified pool of applicants from across the country; Aim 2: Provide an inspiring didactic program that is tailored to each applicants learning agenda; Aim 3: Acquaint trainees with the ongoing approaches for basic, computational and/or translational research related to human disease; Aim 4: Mentor the trainees in the design, execution, evaluation and presentation of experiments leading to original research and giving the trainees the skills required for independent careers in academics. Through this program, trainees will gain knowledge and technical skills to fully understand and evaluate the pathogenesis of disease in humans as well as animal models of human disease through both didactic coursework and applied training in microbiology, immunology, computational studies and comparative medicine. Trainees will be able to find mentorship from a successful group of scientists who are dedicated to research training. The mentors/thesis advisors are comprised of experienced preceptors from basic and translational research programs in microbiology, immunology, cancer, neurobiology, evolution, bioinformatics and comparative medicine that include a cadre of veterinarians with an established record in post-graduate training and mentorship of DVM graduates. Their research programs utilize collaborative and multi-disciplinary approaches employing state-of-the-art techniques in cell biology, microbiology, immunology, systems biology, bioinformatics and comparative pathology. By observing strong, interactive programs in multiple departments at UCSD and throughout the research community in San Diego, the trainees will have an outstanding opportunity to pursue an agenda for successful professional development. This training program will be administered by faculty associated with the UCSD Center for Veterinary Sciences and Comparative Medicine. As a result of this training program, trainees will gain a comprehensive understanding of hypothesis-based research and gain knowledge and skills required for productive careers in academics that will address the national needs for the development of skilled scientists in mouse pathobiology and comparative medicine relevant to human health.