UCSD Research Training Program for Veterinarians

描述(由申请者提供)：目前需要在基础和翻译研究方面受过培训的有才华的兽医科学家，他们应用“同一健康”的原则来发现下一代医学的进步，以改善人类的健康。这项新的机构T32拨款申请旨在为兽医创建一个杰出的计划，以获取基础科学、比较医学和转化研究方面的知识和技能，以开发和应用人类疾病模型，以改善人类健康。我们培训计划的具体目标是在生物医学研究的广泛领域培养DVM研究人员的发展，期望这些人将来成为学术机构或行业的独立研究人员。这将通过追求以下具体目标来实现：目标1)确定来自全国各地的多样化和合格的申请者人才库；目标2)提供一个鼓舞人心的教学计划，为每个申请者的学习议程量身定做；目标3)使受训人员熟悉与人类疾病有关的基础研究和翻译研究正在进行的方法；目标4)指导受训人员设计、执行、评估和演示导致原创研究的实验，并为受训人员提供独立职业生涯所需的技能 学者。通过这项计划，学员将获得知识和技术技能，通过教学课程和微生物学、免疫学和比较医学的应用培训，全面了解和评估人类疾病的发病机制以及人类疾病的动物模型。学员将能够从一群致力于研究培训的成功科学家那里找到指导。导师/论文顾问主要由来自微生物学、免疫学和比较医学的基础和转化研究项目的经验丰富的导师组成，其中包括一支在研究生培训和指导DVM毕业生方面有既定记录的兽医干部。他们的研究计划利用协作和多学科方法，采用细胞生物学、微生物学、分子生物学和比较病理学的最新技术。通过观察加州大学圣地亚哥分校多个部门和整个圣地亚哥研究社区的强大互动项目，学员将有一个绝佳的机会追求成功的职业发展议程。该培训计划将由与加州大学圣迭戈分校兽医科学和比较医学中心相关的教职员工管理。作为这一培训计划的结果，学员将获得对基于假设的研究的全面了解，并获得在学术领域从事生产性职业所需的知识和技能，这些知识和技能将满足国家对培养与人类健康相关的老鼠病理生物学和比较医学方面的熟练科学家的需求。

DESCRIPTION (provided by applicant): There is an existing need for talented veterinary scientists trained in basic and translational research who apply the principles of "One Health" to discover the next generation of advances in medicine for the improvement of health in humans. This application for a new institutional T32 grant seeks funds to create an outstanding program for veterinarians to acquire the knowledge and skills in basic science, comparative medicine and translational research in order to develop and apply models of human disease for the purpose of improving human health. The specific goal of our Training Program is to nurture the development of DVM investigators in the broad field of biomedical research with the expectation that these individuals will go on to become independent investigators at academic institutions or industry. This will be achieved by pursing the following Specific Aims: Aim 1) identify a diverse and well-qualified pool of applicants from across the country; Aim 2) provide an inspiring didactic program that is tailored to each applicants learning agenda; Aim 3) acquaint trainees with the ongoing approaches for basic and translational research related to human disease; Aim 4) mentor the trainees in the design, execution, evaluation and presentation of experiments leading to original research and giving the trainees the skills required for independent careers in academics. Through this program, trainees will gain knowledge and technical skills to fully understand and evaluate the pathogenesis of disease in humans as well as animal models of human disease through both didactic coursework and applied training in microbiology, immunology and comparative medicine. Trainees will be able to find mentorship from a successful group of scientists who are dedicated to research training. The mentors/thesis advisors are comprised mostly of experienced preceptors from basic and translational research programs in microbiology, immunology and comparative medicine that include a cadre of veterinarians with an established record in post- graduate training and mentorship of DVM graduates. Their research programs utilize collaborative and multi- disciplinary approaches employing state-of-the-art techniques in cell biology, microbiology, molecular biology and comparative pathology. By observing strong, interactive programs in multiple departments at UCSD and throughout the research community in San Diego, the trainees will have an outstanding opportunity to pursue an agenda for successful professional development. This training program will be administered by faculty associated with the UCSD Center for Veterinary Sciences and Comparative Medicine. As a result of this training program, trainees will gain a comprehensive understanding of hypothesis-based research and gain knowledge and skills required for productive careers in academics that will address the national needs for the development of skilled scientists in mouse pathobiology and comparative medicine relevant to human health.