Caribbean, Central, and South America network for HIV Epidemiology (CCASAnet)

加勒比、中美洲和南美洲艾滋病毒流行病学网络 (CCASAnet)

• 批准号: 10415216
• 负责人: Pedro Enrique Cahn
• 金额: $ 313.57万
• 依托单位: VANDERBILT UNIVERSITY MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-06-15 至 2026-04-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10415216
• 关键词: Academic Medical Centers; Acquired Immunodeficiency Syndrome; Address; Adolescent; Argentina; Behavioral; Biometry; Brazil; COVID-19 impact; COVID-19 pandemic; COVID-19 pandemic effects; Caribbean region; Caring; Central America; Chile; Clinic; Clinical; Clinical Data; Clinical Research; Clinical Sciences; Collaborations; Communicable Diseases; Complex; Continuity of Patient Care; Country; Data; Data Coordinating Center; Data Science; Data Set; Data Sources; Databases; Diabetes Mellitus; Diagnostic Procedure; Disease Outcome; Education; Elderly; Epidemic; Epidemiology; Funding; Goals; Growth; HIV; HIV therapy; Haiti; Health; Health Policy; Health Sciences; Healthcare Systems; Honduras; Incubated; Individual; Informatics; Information Sciences; Infrastructure; Injecting drug user; Institution; International; Latin America; Leadership; Life Expectancy; Link; Mentors; Mentorship; Methodology; Methods; Mexico; Migrant; Observational Study; Outcome; Patient-Focused Outcomes; Patients; Persons; Peru; Policies; Population; Pregnant Women; Prevention; Prospective cohort; Public Health; Registries; Reporting; Research; Research Personnel; Resource Informatics; Retrospective cohort; Science; Site; South America; Statistical Data Interpretation; Training Programs; Training Support; Translating; Translational Research; Treatment outcome; Tuberculosis; United States National Institutes of Health; Vulnerable Populations; Work; analytical method; base; biomedical informatics; care delivery; clinical application; clinical care; clinical practice; clinical research site; co-infection; cohort; data framework; data harmonization; data management; data quality; data sharing; data tools; epidemiology study; experience; follow-up; health disparity; improved; innovation; insight; member; men who have sex with men; mortality; novel; novel strategies; population health; preservation; programs; prospective; psychosocial; quality assurance; skills; social health determinants; transcriptomics; transgender; transgender women; treatment program; tuberculosis treatment

PROJECT SUMMARY/ABSTRACT The Caribbean, Central and South America network for HIV epidemiology (CCASAnet) is an established and productive network within the International epidemiology Databases to Evaluate AIDS (leDEA) program. CCASAnet was created in 2006 during the first leDEA funding cycle and has brought together clinical, statistical, epidemiologic, and informatics resources from HIV clinical care and research sites in Argentina, Brazil, Chile, Haiti, Honduras, Mexico, and Peru, along with a coordinating center in Nashville, USA. Together, the members of the CCASAnet collaboration respond to scientific opportunities arising in the region and across HIV research networks worldwide. The CCASAnet Data Coordinating Center at Vanderbilt University Medical Center (VDCC) manages the CCASAnet consortium and works to harmonize and analyze the complex databases generated by participating sites. The VDCC also provides mentoring and education to enhance clinical research and data management capabilities at CCASAnet sites, promote junior researchers, and catalyze ongoing growth of scientific leadership in the region. Over the next five years, CCASAnet will assess inequities in the HIV continuum of care; the impact of the COVID-19 pandemic on HIV care delivery; outcomes in vulnerable populations including migrants, those "lost to follow-up," and pregnant women; determinants and prevention of non- communicable diseases; and treatment outcomes in TB patients with and without HIV. We will also characterize psychosocial, behavioral, and non-communicable disease clinical outcomes in adolescents, transgender, and older persons through new prospective cohorts nested in the CCASAnet retrospective clinical cohort. We will continue to develop and apply innovative biostatistics and informatics methods, grow our productive collaborations with other IeDEA regions, and provide leadership in the site assessment, data harmonization, and data sharing initiatives. Through these activities, CCASAnet 4 will help advance both the science of HIV epidemiology and the information science that underpins international research collaboration.

项目总结/摘要 加勒比、中美洲和南美洲艾滋病毒流行病学网络（CCASAnet）是一个已建立的网络， 国际流行病学数据库评估艾滋病（leDEA）计划内的生产网络。 CCASAnet于2006年在第一个leDEA资助周期期间创建，汇集了临床，统计， 流行病学和信息学资源，来自阿根廷，巴西，智利， 海地、洪都拉斯、墨西哥和秘鲁，沿着以及在美国纳什维尔的协调中心。在一起，成员 CCASAnet合作的一部分，以应对该区域和整个艾滋病毒研究领域出现的科学机会 全球网络。范德比尔特大学医学中心（VDCC）的CCASAnet数据协调中心 管理CCASAnet联盟，并致力于协调和分析由 参与网站VDCC还提供指导和教育，以加强临床研究和数据 CCASAnet站点的管理能力，促进初级研究人员，并促进 该地区的科学领导力。在今后五年中，CCASAnet将评估艾滋病毒连续体中的不公平现象 护理; COVID-19大流行对艾滋病毒护理提供的影响;弱势群体的结果 包括移徙者、“失访”者和孕妇; 传染性疾病;以及有和没有艾滋病毒的结核病患者的治疗结果。我们还将描述 青少年、跨性别者和非传染性疾病患者的社会心理、行为和临床结局 通过嵌套在CCASAnet回顾性临床队列中的新的前瞻性队列对老年人进行研究。我们将 继续开发和应用创新的生物统计学和信息学方法， 与其他IeDEA地区的合作，并在网站评估，数据协调和 数据共享举措。通过这些活动，CCASAnet 4将有助于推动艾滋病毒科学 流行病学和信息科学是国际研究合作的基础。