Caribbean, Central and South America Network for HIV Epidemiology (CCASAnet)

加勒比、中美洲和南美洲艾滋病毒流行病学网络 (CCASAnet)

• 批准号: 9113206
• 负责人: Pedro Enrique Cahn
• 金额: $ 169.72万
• 依托单位: VANDERBILT UNIVERSITY MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-06-15 至 2021-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9113206
• 关键词: AIDS/HIV problem; Acquired Immunodeficiency Syndrome; Address; Adolescent; Adolescent and Young Adult; Adult; Aging; Alcohol or Other Drugs use; Americas; Aptitude; Argentina; Biometry; Brazil; Calcium Channel; Cardiovascular Diseases; Caribbean region; Caring; Central America; Child; Childhood; Chile; Cities; Clinic; Clinical; Clinical Data; Clinical Research; Collaborations; Collection; Communicable Diseases; Complex; Continuity of Patient Care; Country; Data; Data Coordinating Center; Data Quality; Databases; Dengue; Development; Diagnosis; Discipline of obstetrics; Disease; Disease Outcome; Education; Epidemic; Epidemiology; Funding; Grant; Growth; Guidelines; HIV; HIV Infections; HIV antiretroviral; HIV-infected adolescents; Haiti; Health; Health Policy; Healthcare; Heart Diseases; Hepatitis; Honduras; Human Papillomavirus; Human immunodeficiency virus test; Individual; Infection; Infectious Disease Epidemiology; Informatics; Information Sciences; International; Knowledge; Latin America; Lead; Leadership; Liver Fibrosis; Malignant Neoplasms; Manuscripts; Measures; Mentors; Methods; Mexico; Monitor; Observational Study; Outcome; Pattern; Persons; Peru; Population; Populations at Risk; Pregnancy Outcome; Principal Investigator; Public Health; Reporting; Research; Research Design; Research Personnel; Resource Informatics; Science; Shapes; Site; South America; Statistical Methods; Trust; Tuberculosis; United States National Institutes of Health; Universities; Viral; Vulnerable Populations; Work; Writing; antiretroviral therapy; base; clinical care; clinical research site; co-infection; cohort; computerized data processing; data management; epidemiology study; experience; improved; innovation; medication compliance; member; neuropsychiatric disorder; novel; pediatric human immunodeficiency virus; planetary Atmosphere; programs; public health relevance; skills; social stigma; success; tool; transmission process; treatment program; trend

 DESCRIPTION (provided by applicant): The Caribbean, Central and South America network for HIV epidemiology (CCASAnet) is an established and productive network within the International epidemiologic Databases to Evaluate AIDS (leDEA) program. CCASAnet was created in 2006 during the first leDEA funding cycle and has brought together clinical, statistical epidemiologic, and informatics resources from HIV clinical care and research sites in Port-au-Prince, Haiti; Mexico City, Mexico; Tegucigalpa, Honduras; Lima, Peru; Buenos Aires, Argentina; Santiago, Chile; and Rio de Janeiro, Belo Horizonte, and Sao Paulo, Brazil, along with a coordinating center in Nashville, USA. Together, the members of the CCASAnet collaboration respond to scientific opportunities arising in the region and across HIV research networks worldwide. The CCASAnet Data Coordinating Center at Vanderbilt University (VDCC) manages the CCASAnet consortium and works to harmonize and analyze the complex databases generated by participating sites. The VDCC also provides mentoring and education to enhance clinical research and data management capabilities at CCASAnet sites, promote junior researchers, and catalyze ongoing growth of scientific leadership in the region. Over the next five years, CCASAnet will evaluate clinical outcomes and complications related to HIV infection and antiretroviral therapy in the region, and determine the impact of infections other than HIV, particularly tuberculosis, hepatitis, human papillomavirus, and dengue. CCASAnet studies will investigate non-communicable diseases such as cancer and heart disease, regional trends in the HIV epidemic and its impact on vulnerable populations, and other issues of public health importance in Latin America. Additionally, studies will address factors uniquely related to children, adolescents, and young adults with HIV. We will continue to develop and apply innovative biostatistics and informatics methods, grow our productive collaborations with other IeDEA regions, and provide leadership in the site assessment and data harmonization initiatives. Through these activities, CCASAnet 3.0 will help advance both the science of HIV epidemiology and the information science that underpins international research collaboration.

 描述（由申请人提供）：加勒比、中美洲和南美洲艾滋病毒流行病学网络 (CCASAnet) 是国际艾滋病评估流行病学数据库 (leDEA) 计划内已建立且富有成效的网络。 CCASAnet 于 2006 年在第一个 leDEA 资助周期内创建，汇集了海地太子港 HIV 临床护理和研究中心的临床、统计流行病学和信息学资源；墨西哥墨西哥城；洪都拉斯特古西加尔巴；秘鲁利马；阿根廷布宜诺斯艾利斯；智利圣地亚哥；以及巴西的里约热内卢、贝洛奥里藏特和圣保罗，以及美国纳什维尔的一个协调中心。 CCASAnet 协作成员共同应对该地区和全球艾滋病毒研究网络中出现的科学机会。范德比尔特大学的 CCASAnet 数据协调中心 (VDCC) 负责管理 CCASAnet 联盟，并致力于协调和分析参与站点生成的复杂数据库。 VDCC 还提供指导和教育，以增强 CCASAnet 站点的临床研究和数据管理能力、提拔初级研究人员并促进该地区科学领导力的持续发展。未来五年，CCASAnet 将评估该地区与 HIV 感染和抗逆转录病毒治疗相关的临床结果和并发症，并确定 HIV 以外的感染的影响，特别是结核病、肝炎、人乳头瘤病毒和登革热。 CCASAnet 研究将调查癌症和心脏病等非传染性疾病、艾滋病毒流行的区域趋势及其对弱势群体的影响，以及拉丁美洲其他具有重要公共卫生意义的问题。此外，研究还将探讨与感染艾滋病毒的儿童、青少年和年轻人相关的独特因素。我们将继续开发和应用创新的生物统计学和信息学方法，发展与其他 IeDEA 区域的富有成效的合作，并在现场评估和数据协调计划中发挥领导作用。通过这些活动，CCASAnet 3.0 将帮助推进艾滋病毒流行病学科学和支撑国际研究合作的信息科学。