Administrative Core

项目摘要/摘要 加州大学天然产物神经科学卓越研究中心(CORE-NPN) 密西西比州药学院(UM)，十年前通过科布雷赠款发起，已经开发出一种 致力于评估天然产品对中枢神经系统影响的多学科团队 (CNS)。该中心现在有潜力开发和维持一个创新的和独立资助的 研究中心专注于治疗与神经系统相关的疾病。行政管理的核心 核心-NPN培养了一支科学家团队，致力于加强我们基础， 天然产物与神经药理学交界处的转化性、创业性研究项目。 行政核心将继续组织指导支助、指导委员会(SC)会议、 外部咨询委员会(EAC)会议、杰出讲座系列、每月会议(Ignite- COBRE-会谈)、年度CORE-NPN专题讨论会、编写进度报告、审查试点项目 应用程序、预算管理协助以及Research Core可能出现的冲突解决 用法。此外，行政核心将确保按服务收费的业务与 大学政策，跟踪和监测核心使用情况，评估核心运营，组织年度核心研究 天，管理代金券计划，促进与密歇根大学神经科学星座的合作并建立 与IDEA和其他项目建立合作伙伴关系。在建立了一大批调查人员后，这些调查人员在 COBRE第一阶段和第二阶段的核心-NPN，第三阶段的目标是鼓励教职员工 合并我们在天然产物和神经药理学方面的研究计划，并促进P01/P50/U19拨款 申请。行政核心的活动将被组织起来，使核心--NPN成为一个成熟的 和可持续发展中心。帮助实现我们的目标的具体目标是：具体目标1：提高音质 通过合作和培养研究工作组，提高核心--NPN教员的竞争力。 这将促进新研究的发展，并促进核心-NPN科学家之间的互动 以及其他IDEA项目的教职员工。具体目标二：加快有前途的研究 CORE-NPN的教员通过使用严格指导的试点项目方案。最好的新奇想法 来自特定目标1将获得种子资金，以支持关键数据的生成以支持新的 有竞争力的拨款申请，或进一步开发临床或商业产品。具体目标3：奋发有为 研究核心的基础设施，以丰富我们的研究工作并加强核心 可持续发展。研究核心将得到支持，以确保它们是最先进的设施。这将是 在机构支持和有计划的外展计划以及在内外的合作下完成 第三阶段。

PROJECT SUMMARY/ABSTRACT The Center of Research Excellence in Natural Products Neuroscience (CORE-NPN) at The University of Mississippi School of Pharmacy (UM), initiated ten years ago through a COBRE grant, has developed a multidisciplinary team committed to evaluating the effects of natural products on the central nervous system (CNS). The Center now has the potential to develop and sustain an innovative and independently funded research center focused on treating disorders associated with the nervous system. The Administrative Core of the CORE-NPN has cultivated a team of scientists engaged in strengthening the competitiveness of our basic, translational, and entrepreneurial research projects at the interface of natural products and neuropharmacology. The Administrative Core will continue to organize mentoring support, Steering Committee (SC) meetings, External Advisory Council (EAC) meetings, the Distinguished Lectureship Series, the monthly meetings (Ignite- COBRE-Talks), the Annual CORE-NPN Symposium, preparation of Progress Reports, review of Pilot Project Applications, assistance in management of budgets, and conflict resolution that might arise with Research Core usage. Additionally, the Administrative Core will ensure that fee-for-service operations are consistent with University policies, track and monitor Core usage, evaluate Core operations, organize Annual Core Research Days, manage the Voucher program, foster collaborations with the UM Neuroscience Constellation and build partnerships with IDeA and other programs. Having built a critical mass of investigators who were funded during COBRE Phases I and II of the CORE-NPN, the objectives of Phase III will be to encourage faculty members to coalesce our research program in natural products and neuropharmacology and foster P01/P50/U19 grant applications. The activities of the Administrative Core will be structured so the CORE-NPN becomes a mature and sustainable Center. The specific aims to help accomplish our goals are: Specific Aim 1: To enhance sound competitiveness of the CORE-NPN faculty through collaborations and by fostering research working groups. This will facilitate the development of novel research and foster interactions among the CORE-NPN scientists and with faculty members of other IDeA programs. Specific Aim 2: To accelerate the research of promising faculty of the CORE-NPN through the Pilot Project Program using rigorous mentoring. The best novel ideas that come from Specific Aim 1 will be provided seed money to support the generation of critical data to support new competitive grant applications or to further develop a clinical or commercial product. Specific Aim 3: To advance an infrastructure of the Research Cores in order to enrich our research efforts and to reinforce the Cores sustainability. Research Cores will be supported to ensure they are state-of-the-art facilities. This will be accomplished with institutional support and planned outreach programs and collaborations during and beyond Phase III.