Core E -Community Engagement and Clinical Informatics Core

核心E：项目摘要/摘要：艾滋病毒的流行，在当地和全球，是由长期存在的 不平等艾滋病毒研究工作必须与这些国家的需求、优先事项和优势保持一致， 这些社区长期以来一直承受着艾滋病毒不平等的负担。因此，UCLA-CDU CFAR 社区参与和临床信息学核心（CECIC）旨在加速当前艾滋病毒的影响 为洛杉矶（LA）县以及非洲和拉丁美洲社区的弱势群体开展研究 美国参考该核心将与学术和社区合作伙伴、洛杉矶县诊所和全球合作伙伴一起， * 开展多方向的协作努力，制定和实施降低艾滋病毒发病率的新方法， 改善PLWH治疗结果，并在有色人种社区中促进无ART缓解 受艾滋病毒的严重影响。CECIC的核心是CDU的社区学院，这是一个独特的计划， 哪些影响社区健康成果的社区领袖获得了教师 在CDU任职。一名社区教师将担任该核心的联合主任。其目的是 核心是：1）：提供以社区为基础的示范性研究方面的培训和技术援助 支持CFAR调查人员和社区合作伙伴之间的富有成效的合作; 2）扩大CBPR 在洛杉矶和全球范围内，通过战略性地使用 社区咨询委员会（CAB）和研究登记处（RSVP）;以及3）建立基础设施， 临床信息学支持的研究与社区医疗提供者在洛杉矶，以支持分析 电子健康记录数据，并告知最佳做法，以响应患者和提供者不断变化的需求。的 CECIC将位于Charles R。德鲁医学与科学大学（CDU），并由CDU领导 investigators. CDU是洛杉矶县唯一指定的少数民族服务健康科学大学， 人口超过1000万居民，其中70%来自少数民族社区。基民盟服务于 作为当地服务区150万人口的唯一学术健康科学和医学研究中心， 居民，美国最大的服务不足的城市地区，主要由拉丁裔（68%）和 黑人/非洲裔美国人（28%）。周边地区艾滋病发病率居全国第二 在该县13岁及以上的人群中，几乎是全国平均水平的两倍， 艾滋病毒感染相关死亡率。这使得CDU成为支持CBPR的理想场所，承诺 对周边社区的直接影响。通过推广先进的CBPR实践，CECIC将扩大 改变洛杉矶和全球艾滋病研究的方式。我们将培养新一代的 早期调查人员与代表性不足的少数民族调查人员之间的伙伴关系，以及社区- 艾滋病毒/艾滋病的预防和治疗是一项重要的工作，旨在减少艾滋病毒的发病率和改善护理结果。

Core E: Project Summary/Abstract: The HIV epidemic, locally and globally, is fueled by long-standing inequities. It is imperative that HIV research efforts align with the needs, priorities, and strengths of those communities that for too long have shouldered the burden of HIV disparities. Thus, the UCLA-CDU CFAR Community Engagement and Clinical Informatics Core (CECIC) aims to accelerate the impact of current HIV research for vulnerable populations in Los Angeles (LA) County and communities across Africa and Latin America. This Core will engage academic and community partners, LA County clinics, and global partners in a multidirectional and collaborative effort to develop and implement new ways to decrease the incidence of HIV, improve treatment outcomes of PLWH, and advance ART-free remission in communities of color disproportionately impacted by HIV. The heart of the CECIC is CDU's Community Faculty, a unique program in which community leaders who have impacted the health outcomes of their communities receive a faculty appointment at CDU. A Community Faculty member will be one of the co-directors of this core. The aims of this core are: 1): To provide training and technical assistance in Community-Based Participatory Research (CBPR) to support productive collaborations between CFAR investigators and community partners; 2) To expand CBPR to populations disproportionately impacted by HIV in Los Angeles and globally through the strategic use of Community Advisory Boards (CABs) and a research registry (RSVP); and 3) To create infrastructure to conduct Clinical Informatics-supported research with community medical providers in Los Angeles to support analysis of EHR data and to inform best practices that are responsive to patients' and providers' changing needs. The CECIC will be housed at Charles R. Drew University of Medicine and Science (CDU) and led by CDU investigators. CDU is the only designated minority-serving health-sciences university in LA County with a population of more than 10 million residents, 70 percent of whom are from minority communities. CDU serves as the only academic health sciences and medical research center for the local service area's 1.5 million residents, the largest underserved urban area in the US, made up predominantly of Latinx (68%) and Black/African-American (28%) individuals. The surrounding area has the second highest incidence of HIV/AIDS among people aged 13 years and older in the county, almost twice the national average, and the second highest HIV-infection related mortality rate. This makes CDU the ideal site to support CBPR that promises to have immediate impact on surrounding communities. By promoting advanced CBPR practices, the CECIC will expand and transform how HIV research is conducted in Los Angeles and globally. We will foster a new generation of partnerships between early stage investigators and underrepresented minority investigators, and community- based organizations to decrease HIV incidence and improve care outcomes.