Training Program in Childhood Neuropsychiatric Disorders

项目摘要 这是耶鲁大学T32培训资助计划的5年续期申请书 儿童神经精神障碍“(T32 MH018268)。我们的节目重点是准备 临床和基础科学领域的科学家，寻求独立的职业生涯，成为领域领先的研究人员， 对儿童神经精神障碍进行研究。像我们这样的培训项目非常紧迫 需要考虑到：1)受重大精神疾病影响或有患重大精神疾病风险的儿童人数众多； 2)与他们的护理相关的相当大的社会成本；3)有限的效力和效力 现有的治疗和预防方案；4)现场现役调查人员数量较少； 5)出现了尚未完全实现的相关科技进步。 34年来，我们共招聘了107名T32博士后研究员。这些实习生中的大多数 妇女(56%)和近20%的少数族裔代表不足。在过去的15年里， 86%的学员完成了至少两年的T32奖学金。大多数实习生， 80%的人继续积极参与有关儿童神经精神障碍的研究。 大多数学员发表了多篇同行评审的论文，许多学员获得了 无数的独立研究补助金和职业发展奖。他们的工作已经获得了 在国际上享有盛誉，我们的许多毕业生都是各自领域的领军人物。独一无二的， 这项T32计划与一个非常成功的六年儿童、青少年和成人一体化计划完全结合在一起 儿童精神病学研究和临床住院医师培训计划。在这次更新中，我们寻求扩大 根据我们现有的合作，包括与毗邻部门和 与附近的学术机构合作，重点是儿童心理健康。我们包括明确的培训 在团队科学方面。我们相信，这一培训将提高我们学员的成功，重新定位文化。 更好的支持、更大的回报和更高的导师质量 临床和转化性研究。我们将继续把重点放在职业发展上 通过提供个人指导和团队科学的体验式培训，并辅之以 说教活动。在培训过程的早期，为每个学员制定了个性化的培训计划 并在整个过程中受到密切监测。提高写作技巧，指导 平衡个人生活和职业生涯，以及接触跨学科的合作导师 说明我们的T32奖学金计划的特点。

Project Summary This is an application for a 5-year renewal of the Yale University’s T32 Training Grant "Training Program in Childhood Neuropsychiatric Disorders" (T32 MH018268). Our program focuses on preparing scientists, in both clinical and basic sciences, for independent careers as field- leading investigators, conducting research on childhood neuropsychiatric disorders. Training programs like ours are urgently needed given: 1) the large number of children affected by or at risk to develop major mental illnesses; 2) the considerable costs to society associated with their care; 3) the limited efficacy and effectiveness of available treatment and prevention programs; 4) the small number of active investigators in the field; and 5) the emergence of relevant scientific and technological advances that have yet to be fully realized. Over the past 34 years, we have recruited 107 T32 Postdoctoral Fellows. A majority of these trainees have been women (56%) and close to 20% have been underrepresented minorities. In the last 15 years, 86% percent of the trainees completed at least two years of the T32 Fellowship. A majority of trainees, 80% continue to be actively involved in research concerning Childhood Neuropsychiatric Disorders. Most trainees have published multiple peer-reviewed papers and many trainees have obtained numerous independent research grants and career development awards. Their work has garnered international acclaim and many of our graduates are leading figures in their respective fields. Uniquely, this T32 program is fully united with a highly successful six-year integrated child, adolescent and adult research and clinical residency training program in child psychiatry. In this renewal, we seek to expand upon our existing collaborations involving joint training opportunities with adjoining departments and with nearby academic institutions with an emphasis in child mental health. We include explicit training in team science. We believe this training will augment the success of our trainees, reorienting the culture of the academic institution to better support, greater reward, and an enhanced quality of mentorship in clinical and translational research. We will continue to place a major emphasis on career development by providing individual mentoring along with experiential training in team science, complemented by didactic activities. A personalized training plan is developed for each trainee early during the course of the Fellowship and is monitored closely throughout. Enhancement of writing skills, guidance on balancing personal life and professional career, and exposure to cross-disciplinary co-mentors characterize our T32 Fellowship program.