Core A: Administrative Core
核心A:行政核心
基本信息
- 批准号:10468306
- 负责人:
- 金额:$ 38.93万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2021
- 资助国家:美国
- 起止时间:2021-08-15 至 2026-06-30
- 项目状态:未结题
- 来源:
- 关键词:AccountabilityAdministrative PersonnelAdvisory CommitteesAlzheimer&aposs DiseaseAlzheimer&aposs disease related dementiaAreaBiologicalBostonBudgetsClinicalCollaborationsCommunitiesCommunity ActionsData SetDevelopmentEducational workshopEnsureFeedbackFosteringFramingham Heart StudyGoalsHeartHeterogeneityIndividualIndustryInfrastructureInteractive CommunicationInternationalKnowledgeLate EffectsLeadershipMedical centerMentorsMissionMolecular ProfilingMonitorNaturePerformancePoliciesPreventionProcessProcess AssessmentProgram ReviewsRecommendationReportingResearchResearch EthicsResearch PersonnelResourcesReview CommitteeRoleScientistSelf AssessmentSiteSourceSpecimenStrategic visionStructureTechnologyThinkingTimeTrainingUnited States National Institutes of HealthUniversitiesWomen&aposs HealthWorkblack womencareer developmentcohortcommunity organizationsdigitaldisease heterogeneityhead impacthigh riskhigh standardhuman subjectimprovedinnovationmedical schoolsnext generationnovelpreventprogramspublic-private partnershipsymposium
项目摘要
Since its inception in 1996, the Boston University (BU) Alzheimer Disease (AD) Research Center (ADRC) has
had a singular mission to facilitate leading-edge research on Alzheimer's disease (AD) and AD related
dementias (ADRD). The function of the Administrative Core (AC) is to ensure that administrative processes are
in place to support this mission. The Core manages and coordinates internal interactions between the ADRC
director and core leaders, interactions between the BU ADRC and investigators at BU and elsewhere, BU
administration, staff at NIA, and local and national community organizations. The AC integrates, coordinates,
directs and plans all BU ADRC activities and ensures compliance with all human subjects, scientific integrity,
and financial policy requirements of NIH. This includes providing an effective structure to support our scientific
efforts focused on studying AD/ADRD disease heterogeneity, ensuring the availability of our diverse cohorts,
and supporting and implementing the themes and goals of the National Alzheimer's Plan Project Act (NAPA).
The progress of the ADRC as a whole and its individual core component will be monitored to ensure
accountability to NAPA and NIA milestones and goals. The AC fosters innovative AD/ADRD research by
providing visionary leadership and by facilitating cross-core interactions and coordinating the provision of
resources to support qualified investigators at BU and other local, national, and international research
programs. The AC facilitates partnerships with the local, regional, national and international AD/ADRD
research community to support high-impact AD/ADRD research. The AC will ensure that all mandated data
sets are submitted to NACC in an accurate and timely manner and that biological specimens are submitted to
the NCRAD. The AC ensures that we support and inform the communities we serve regarding the benefits of
the BU ADRC and AD/ADRD research and to solicit feedback and advice from them. The AC is under the
leadership of BU ADRC Director Dr. Neil Kowall who reports directly to the Dean of BU School of Medicine. In
his role as BU ADRC Director he is supported by an Executive Committee comprised of BU ADRC core
leaders and other senior thought leaders at BU. Other administrative committees include an External Advisory
Committee, Internal Advisory Committee, and Community Action Council. In collaboration with the BU ADRC
Director, these committees are responsible for coordinating, planning, overseeing, and evaluating all BU ADRC
activities and ensuring the optimal utilization of BU ADRC resources. The AC administers the developmental
project program to support meritorious projects focused on basic or clinical AD/ADRD research. A
Developmental Project Review Panel will be commissioned review, select, and monitor these projects.
Ongoing, interactive communication and input will be solicited from multiple sources, including our institutional
research community, external AD/ADRD experts, and NIA, to strengthen and improve our Center's
performance.
自1996年成立以来,波士顿大学阿尔茨海默病(AD)研究中心(ADRC)
我肩负着促进阿尔茨海默病(AD)及其相关前沿研究的独特使命
痴呆(ADRD)。行政核心(AC)的职能是确保行政程序
以支持这项任务。核心管理和协调ADRC之间的内部交互
董事和核心领导,BU ADRC与BU和其他地方的调查人员之间的互动
行政部门、NIA的工作人员以及地方和国家社区组织。AC集成、协调、
指导和计划所有BU ADRC活动,并确保符合所有人类受试者、科学诚信、
以及美国国立卫生研究院的财务政策要求。这包括提供一个有效的结构来支持我们的科学
工作重点是研究AD/ADRD疾病的异质性,确保我们不同队列的可用性,
支持和实施《国家阿尔茨海默氏症计划项目法案》的主题和目标。
将监测整个非盟及其个别核心组成部分的进展情况,以确保
对国家适应行动方案和国家行动局的里程碑和目标负责。AC通过以下方式促进创新的AD/ADRD研究
提供有远见的领导,通过促进跨核心互动和协调提供
用于支持BU的合格调查人员以及其他地方、国家和国际研究的资源
程序。咨询委员会促进与地方、区域、国家和国际反兴奋剂机构/反兴奋剂机构的伙伴关系
研究界支持高影响力的AD/ADRD研究。审计委员会将确保所有强制数据
SET以准确和及时的方式提交给NACC,并将生物标本提交给
NCRAD。协调委员会确保我们支持我们所服务的社区,并告知他们以下好处
BU ADRC和AD/ADRD进行研究,并征求他们的反馈和建议。空调系统是在
BU ADRC主任尼尔·科沃尔博士直接向BU医学院院长汇报工作。在……里面
他作为BU ADRC主任的角色他得到了由BU ADRC核心组成的执行委员会的支持
北卡罗来纳大学的领袖和其他高级思想领袖。其他行政委员会包括一名外部顾问
委员会、内部咨询委员会和社区行动委员会。与BU ADRC合作
主任,这些委员会负责协调、规划、监督和评估所有BU ADRC
活动,并确保BU ADRC资源的最佳利用。AC管理发展
项目计划,以支持侧重于基础或临床AD/ADRD研究的有价值的项目。一个
将委托发展项目审查小组对这些项目进行审查、选择和监测。
将从多个来源征求持续的、互动的沟通和意见,包括我们的机构
研究界、外部AD/ADRD专家和NIA,以加强和改进我们中心的
性能。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Neil W. Kowall其他文献
Multi-ancestry genome-wide meta-analysis of 56,241 individuals identifies known and novel cross-population and ancestry-specific associations as novel risk loci for Alzheimer’s disease
- DOI:
10.1186/s13059-025-03564-z - 发表时间:
2025-07-17 - 期刊:
- 影响因子:9.400
- 作者:
Farid Rajabli;Penelope Benchek;Giuseppe Tosto;Nicholas Kushch;Jin Sha;Katrina Bazemore;Congcong Zhu;Wan-Ping Lee;Jacob Haut;Kara L. Hamilton-Nelson;Nicholas R. Wheeler;Yi Zhao;John J. Farrell;Michelle A. Grunin;Yuk Yee Leung;Pavel P. Kuksa;Donghe Li;Eder Lucio da Fonseca;Jesse B. Mez;Ellen L. Palmer;Jagan Pillai;Richard M. Sherva;Yeunjoo E. Song;Xiaoling Zhang;Takeshi Ikeuchi;Taha Iqbal;Omkar Pathak;Otto Valladares;Dolly Reyes-Dumeyer;Amanda B. Kuzma;Erin Abner;Larry D. Adams;Perrie M. Adams;Alyssa Aguirre;Marilyn S. Albert;Roger L. Albin;Mariet Allen;Lisa Alvarez;Liana G. Apostolova;Steven E. Arnold;Sanjay Asthana;Craig S. Atwood;Sanford Auerbach;Gayle Ayres;Clinton T. Baldwin;Robert C. Barber;Lisa L. Barnes;Sandra Barral;Thomas G. Beach;James T. Becker;Gary W. Beecham;Duane Beekly;Bruno A. Benitez;David Bennett;John Bertelson;Thomas D. Bird;Deborah Blacker;Bradley F. Boeve;James D. Bowen;Adam Boxer;James Brewer;James R. Burke;Jeffrey M. Burns;Joseph D. Buxbaum;Nigel J. Cairns;Laura B. Cantwell;Chuanhai Cao;Christopher S. Carlson;Cynthia M. Carlsson;Regina M. Carney;Minerva M. Carrasquillo;Scott Chasse;Marie-Francoise Chesselet;Nathaniel A. Chin;Helena C. Chui;Jaeyoon Chung;Suzanne Craft;Paul K. Crane;David H. Cribbs;Elizabeth A. Crocco;Carlos Cruchaga;Michael L. Cuccaro;Munro Cullum;Eveleen Darby;Barbara Davis;Philip L. De Jager;Charles DeCarli;John DeToledo;Malcolm Dick;Dennis W. Dickson;Beth A. Dombroski;Rachelle S. Doody;Ranjan Duara;NIlüfer Ertekin-Taner;Denis A. Evans;Kelley M. Faber;Thomas J. Fairchild;Kenneth B. Fallon;David W. Fardo;Martin R. Farlow;Victoria Fernandez-Hernandez;Steven Ferris;Robert P. Friedland;Tatiana M. Foroud;Matthew P. Frosch;Brian Fulton-Howard;Douglas R. Galasko;Adriana Gamboa;Marla Gearing;Daniel H. Geschwind;Bernardino Ghetti;John R. Gilbert;Rodney C.P. Go;Alison M. Goate;Thomas J. Grabowski;Neill R. Graff-Radford;Robert C. Green;John H. Growdon;Hakon Hakonarson;James Hall;Ronald L. Hamilton;Oscar Harari;John Hardy;Lindy E. Harrell;Elizabeth Head;Victor W. Henderson;Michelle Hernandez;Timothy Hohman;Lawrence S. Honig;Ryan M. Huebinger;Matthew J. Huentelman;Christine M. Hulette;Bradley T. Hyman;Linda S. Hynan;Laura Ibanez;Gail P. Jarvik;Suman Jayadev;Lee-Way Jin;Kim Johnson;Leigh Johnson;M. Ilyas Kamboh;Anna M. Karydas;Mindy J. Katz;John S. Kauwe;Jeffrey A. Kaye;C. Dirk Keene;Aisha Khaleeq;Masataka Kikuchi;Ronald Kim;Janice Knebl;Neil W. Kowall;Joel H. Kramer;Walter A. Kukull;Frank M. LaFerla;James J. Lah;Eric B. Larson;Alan Lerner;James B. Leverenz;Allan I. Levey;Andrew P. Lieberman;Richard B. Lipton;Mark Logue;Oscar L. Lopez;Kathryn L. Lunetta;Constantine G. Lyketsos;Douglas Mains;Flanagan E. Margaret;Daniel C. Marson;Eden RR. Martin;Frank Martiniuk;Deborah C. Mash;Eliezer Masliah;Paul Massman;Arjun Masurkar;Wayne C. McCormick;Susan M. McCurry;Andrew N. McDavid;Stefan McDonough;Ann C. McKee;Marsel Mesulam;Bruce L. Miller;Carol A. Miller;Joshua W. Miller;Thomas J. Montine;Edwin S. Monuki;John C. Morris;Shubhabrata Mukherjee;Amanda J. Myers;Trung Nguyen;Thomas Obisesan;Sid O’Bryant;John M. Olichney;Marcia Ory;Raymond Palmer;Joseph E. Parisi;Henry L. Paulson;Valory Pavlik;David Paydarfar;Victoria Perez;Elaine Peskind;Ronald C. Petersen;Helen Petrovitch;Aimee Pierce;Marsha Polk;Wayne W. Poon;Huntington Potter;Liming Qu;Mary Quiceno;Joseph F. Quinn;Ashok Raj;Murray Raskind;Eric M. Reiman;Barry Reisberg;Joan S. Reisch;John M. Ringman;Erik D. Roberson;Monica Rodriguear;Ekaterina Rogaeva;Howard J. Rosen;Roger N. Rosenberg;Donald R. Royall;Marwan Sabbagh;A. Dessa Sadovnick;Mark A. Sager;Mary Sano;Andrew J. Saykin;Julie A. Schneider;Lon S. Schneider;William W. Seeley;Susan H. Slifer;Scott Small;Amanda G. Smith;Janet P. Smith;Joshua A. Sonnen;Salvatore Spina;Peter St George-Hyslop;Takiyah D. Starks;Robert A. Stern;Alan B. Stevens;Stephen M. Strittmatter;David Sultzer;Russell H. Swerdlow;Rudolph E. Tanzi;Jeffrey L. Tilson;John Q. Trojanowski;Juan C. Troncoso;Magda Tsolaki;Debby W. Tsuang;Vivianna M. Van Deerlin;Linda J. van Eldik;Jeffery M. Vance;Badri N. Vardarajan;Robert Vassar;Harry V. Vinters;Jean-Paul Vonsattel;Sandra Weintraub;Kathleen A. Welsh-Bohmer;Patrice L. Whitehead;Ellen M. Wijsman;Kirk C. Wilhelmsen;Benjamin Williams;Jennifer Williamson;Henrik Wilms;Thomas S. Wingo;Thomas Wisniewski;Randall L. Woltjer;Martin Woon;Clinton B. Wright;Chuang-Kuo Wu;Steven G. Younkin;Chang-En Yu;Lei Yu;Xiongwei Zhu;Brian W. Kunkle;William S. Bush;Akinori Miyashita;Goldie S. Byrd;Li-San Wang;Lindsay A. Farrer;Jonathan L. Haines;Richard Mayeux;Margaret A. Pericak-Vance;Gerard D. Schellenberg;Gyungah R. Jun;Christiane Reitz;Adam C. Naj - 通讯作者:
Adam C. Naj
Multiomics analysis to explore blood metabolite biomarkers in an Alzheimer’s Disease Neuroimaging Initiative cohort
多组学分析探索阿尔茨海默病神经影像倡议队列中的血液代谢生物标志物
- DOI:
10.1038/s41598-024-56837-1 - 发表时间:
2024 - 期刊:
- 影响因子:4.6
- 作者:
Takaki Oka;Yuki Matsuzawa;Momoka Tsuneyoshi;Yoshitaka Nakamura;Ken Aoshima;H. Tsugawa;Michael Paul Ronald Clifford R. William John Q. Arthur W. Weiner Aisen Petersen Jack Jagust Trojanowki Toga ;Michael Weiner;P. Aisen;Ron Petersen;Clifford R Jack;William Jagust;J. Trojanowki;Arthur W Toga;L. Beckett;Robert C. Green;Andrew J. Saykin;John C. Morris;Leslie M. Shaw;Enchi Liu;T. Montine;R. G. Thomas;Michael Donohue;Sarah Walter;D. Gessert;T. Sather;G. Jiminez;Danielle Harvey;M. Bernstein;Nick Fox;Paul Thompson;N. Schuff;Charlie S. DeCarli;B. Borowski;J. Gunter;Matthew Senjem;P. Vemuri;David Jones;K. Kantarci;C. Ward;Robert A. Koeppe;Norman L. Foster;Eric M Reiman;Kewei Chen;C. Mathis;Susan Landau;Nigel J. Cairns;E. Householder;Lisa Taylor Reinwald;V. Lee;M. Korecka;M. Figurski;K. Crawford;S. Neu;Tatiana M Foroud;S. Potkin;L. Shen;Faber Kelley;Sungeun Kim;K. Nho;Zaven Kachaturian;Richard Frank;Peter J. Snyder;S. Molchan;J. Kaye;Joseph Quinn;B. Lind;R. Carter;S. Dolen;Lon S. Schneider;S. Pawluczyk;Mauricio Beccera;L. Teodoro;B. Spann;J. Brewer;H. Vanderswag;A. Fleisher;J. Heidebrink;J. Lord;S. Mason;C. Albers;D. Knopman;K. Johnson;Rachelle S. Doody;Javier Villanueva Meyer;M. Chowdhury;S. Rountree;M. Dang;Y. Stern;Lawrence S. Honig;Karen L. Bell;B. Ances;John C. Morris;M. Carroll;Sue Leon;E. Householder;M. Mintun;S. Schneider;A. Oliver;D. Marson;R. Griffith;D. Clark;David S Geldmacher;J. Brockington;Erik Roberson;H. Grossman;Effie M. Mitsis;L. de Toledo‐Morrell;R. Shah;R. Duara;D. Varon;Maria T. Greig;Peggy Roberts;Marilyn S. Albert;C. Onyike;D. D’Agostino;S. Kielb;James E. Galvin;D. Pogorelec;Brittany Cerbone;Christina A. Michel;H. Rusinek;Mony J. de Leon;Lidia Glodzik;S. de Santi;P. Doraiswamy;J. Petrella;T. Wong;Steven E. Arnold;J. Karlawish;David A. Wolk;Charles D. Smith;G. Jicha;Peter Hardy;P. Sinha;Elizabeth Oates;G. Conrad;Oscar L. Lopez;M. Oakley;D. Simpson;A. Porsteinsson;B. Goldstein;K. Martin;K. Makino;M. Ismail;C. Brand;R. Mulnard;G. Thai;Catherine Mc Adams Ortiz;Kyle Womack;D. Mathews;M. Quiceno;R. D. Arrastia;Richard D. King;Myron Weiner;K. M. Cook;Michael D. Devous;A. Levey;J. Lah;J. Cellar;Jeffrey M. Burns;H. Anderson;R. Swerdlow;Liana G. Apostolova;K. Tingus;Ellen Woo;Daniel H. S. Silverman;Po H. Lu;G. Bartzokis;Neill R. Graff Radford;F. Parfitt;Tracy Kendall;Heather K. Johnson;Marty Farlow;A. Hake;Brandy R. Matthews;S. Herring;Cynthia Hunt;Christopher H. van Dyck;Richard E. Carson;M. Macavoy;H. Chertkow;Howard Bergman;C. Hosein;S. Black;B. Stefanovic;Curtis Caldwell;G. R. Hsiung;H. Feldman;B. Mudge;M. Assaly;Andrew Kertesz;J. Rogers;D. Trost;C. Bernick;D. Munic;D. Kerwin;M.;K. Lipowski;Chuang‐Kuo Wu;N. Johnson;C. Sadowsky;Walter Martínez;Teresa Villena;R. S. Turner;K. Johnson;B. Reynolds;R. Sperling;Keith A. Johnson;G. Marshall;Meghan T. Frey;Jerome A. Yesavage;Joy Taylor;B. Lane;A. Rosen;Jared S. Tinklenberg;M. Sabbagh;C. Belden;S. Jacobson;Sherye A. Sirrel;Neil W. Kowall;Ronald J Killiany;A. Budson;A. Norbash;P. L. Johnson;T. Obisesan;S. Wolday;Joanne S. Allard;Alan J Lerner;P. Ogrocki;Leon Hudson;E. Fletcher;O. Carmichael;J. Olichney;Charlie S. DeCarli;S. Kittur;Michael Borrie;T. Lee;Rob Bartha;S. Johnson;Sanjay Asthana;C. Carlsson;S. Potkin;Adrian Preda;D. Nguyen;P. Tariot;A. Fleisher;Stephanie A. Reeder;V. Bates;H. Capote;M. Rainka;D. Scharre;M. Kataki;Anahita Adeli;E. Zimmerman;D. Celmins;Alice D. Brown;G. D. Pearlson;K. Blank;K. Anderson;R. Santulli;T. Kitzmiller;Eben S. Schwartz;K. Sink;J. Williamson;P. Garg;F. Watkins;Brian R. Ott;H. Querfurth;G. Tremont;S. Salloway;P. Malloy;Stephen Correia;H. Rosen;Bruce L. Miller;Jacobo Mintzer;K. Spicer;David Bachman;E. Finger;S. Pasternak;I. Rachinsky;J. Rogers;Andrew Kertesz;D. Drost;N. Pomara;R. Hernando;A. Sarrael;Susan K. Schultz;L. Ponto;H. Shim;K. Smith;N. Relkin;G. Chaing;Lisa Raudin;Amanda G. Smith;K. Fargher;B. A. Raj - 通讯作者:
B. A. Raj
VA’s National PTSD Brain Bank: a National Resource for Research
- DOI:
10.1007/s11920-017-0822-6 - 发表时间:
2017-08-25 - 期刊:
- 影响因子:6.700
- 作者:
Matthew J. Friedman;Bertrand R. Huber;Christopher B. Brady;Robert J. Ursano;David M. Benedek;Neil W. Kowall;Ann C. McKee - 通讯作者:
Ann C. McKee
p75NTR Antagonistic Cyclic Peptide Decreases the Size of β Amyloid-Induced Brain Inflammation
- DOI:
10.1007/s10571-008-9298-6 - 发表时间:
2008-09-19 - 期刊:
- 影响因子:4.800
- 作者:
Mina Yaar;Bennet L. Arble;Kenneth B. Stewart;Nazer H. Qureshi;Neil W. Kowall;Barbara A. Gilchrest - 通讯作者:
Barbara A. Gilchrest
Neil W. Kowall的其他文献
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{{ truncateString('Neil W. Kowall', 18)}}的其他基金
Boston University Alzheimer's Disease Research Center
波士顿大学阿尔茨海默病研究中心
- 批准号:
10264287 - 财政年份:2021
- 资助金额:
$ 38.93万 - 项目类别:
VA Biorepository: Gulf War Veterans' Illnesses Biorepository
VA 生物储存库:海湾战争退伍军人疾病生物储存库
- 批准号:
9402030 - 财政年份:2014
- 资助金额:
$ 38.93万 - 项目类别:
Epigenetic mechanisms relevant to the pathogenesis of ALS
ALS发病机制相关的表观遗传机制
- 批准号:
8597391 - 财政年份:2011
- 资助金额:
$ 38.93万 - 项目类别:
Alzheimer's disease translational research training
阿尔茨海默病转化研究培训
- 批准号:
8446333 - 财政年份:2011
- 资助金额:
$ 38.93万 - 项目类别:
Epigenetic mechanisms relevant to the pathogenesis of ALS
ALS发病机制相关的表观遗传机制
- 批准号:
8043487 - 财政年份:2011
- 资助金额:
$ 38.93万 - 项目类别:
Alzheimer's disease translational research training
阿尔茨海默病转化研究培训
- 批准号:
8660258 - 财政年份:2011
- 资助金额:
$ 38.93万 - 项目类别:
Epigenetic mechanisms relevant to the pathogenesis of ALS
ALS发病机制相关的表观遗传机制
- 批准号:
8245574 - 财政年份:2011
- 资助金额:
$ 38.93万 - 项目类别:














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