Core A: Administrative Core
核心A:行政核心
基本信息
- 批准号:10652549
- 负责人:
- 金额:$ 39.97万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2021
- 资助国家:美国
- 起止时间:2021-08-15 至 2026-06-30
- 项目状态:未结题
- 来源:
- 关键词:AccelerationAccountabilityAction ResearchAdministrative PersonnelAdvisory CommitteesAlzheimer&aposs DiseaseAlzheimer&aposs disease related dementiaAreaBiologicalBostonBudgetsClinicalCollaborationsCommunitiesCommunity ActionsData SetDevelopmentEarly identificationEducational workshopEnsureFeedbackFosteringFramingham Heart StudyGoalsHeartHeterogeneityIndividualIndustryInfrastructureInstitutionInteractive CommunicationInternationalKnowledgeLate EffectsLeadershipMedical centerMentorsMissionMolecular ProfilingMonitorNaturePerformancePoliciesPreventionProcessProcess AssessmentProgram ReviewsQualifyingRecommendationReportingResearchResearch EthicsResearch PersonnelResourcesReview CommitteeRoleScientistSelf AssessmentSiteSourceSpecimenStrategic visionStructureThinkingTrainingUnited States National Institutes of HealthUniversitiesUniversity adminstrationWomen&aposs HealthWorkblack womencareer developmentcohortcommunity organizationscultural valuesdigital technologydisease heterogeneityhead impacthigh riskhigh standardhuman subjectimprovedinnovationmedical schoolsnext generationnovelpreventprogramspublic-private partnershipsymposium
项目摘要
Since its inception in 1996, the Boston University (BU) Alzheimer Disease (AD) Research Center (ADRC) has
had a singular mission to facilitate leading-edge research on Alzheimer's disease (AD) and AD related
dementias (ADRD). The function of the Administrative Core (AC) is to ensure that administrative processes are
in place to support this mission. The Core manages and coordinates internal interactions between the ADRC
director and core leaders, interactions between the BU ADRC and investigators at BU and elsewhere, BU
administration, staff at NIA, and local and national community organizations. The AC integrates, coordinates,
directs and plans all BU ADRC activities and ensures compliance with all human subjects, scientific integrity,
and financial policy requirements of NIH. This includes providing an effective structure to support our scientific
efforts focused on studying AD/ADRD disease heterogeneity, ensuring the availability of our diverse cohorts,
and supporting and implementing the themes and goals of the National Alzheimer's Plan Project Act (NAPA).
The progress of the ADRC as a whole and its individual core component will be monitored to ensure
accountability to NAPA and NIA milestones and goals. The AC fosters innovative AD/ADRD research by
providing visionary leadership and by facilitating cross-core interactions and coordinating the provision of
resources to support qualified investigators at BU and other local, national, and international research
programs. The AC facilitates partnerships with the local, regional, national and international AD/ADRD
research community to support high-impact AD/ADRD research. The AC will ensure that all mandated data
sets are submitted to NACC in an accurate and timely manner and that biological specimens are submitted to
the NCRAD. The AC ensures that we support and inform the communities we serve regarding the benefits of
the BU ADRC and AD/ADRD research and to solicit feedback and advice from them. The AC is under the
leadership of BU ADRC Director Dr. Neil Kowall who reports directly to the Dean of BU School of Medicine. In
his role as BU ADRC Director he is supported by an Executive Committee comprised of BU ADRC core
leaders and other senior thought leaders at BU. Other administrative committees include an External Advisory
Committee, Internal Advisory Committee, and Community Action Council. In collaboration with the BU ADRC
Director, these committees are responsible for coordinating, planning, overseeing, and evaluating all BU ADRC
activities and ensuring the optimal utilization of BU ADRC resources. The AC administers the developmental
project program to support meritorious projects focused on basic or clinical AD/ADRD research. A
Developmental Project Review Panel will be commissioned review, select, and monitor these projects.
Ongoing, interactive communication and input will be solicited from multiple sources, including our institutional
research community, external AD/ADRD experts, and NIA, to strengthen and improve our Center's
performance.
自1996年成立以来,波士顿大学(BU)阿尔茨海默病(AD)研究中心(ADRC)
有一个单一的使命,以促进领先的研究阿尔茨海默氏病(AD)和AD相关的
痴呆症(ADRD)。行政核心的职能是确保行政程序
来支持这次使命核心管理和协调ADRC之间的内部互动
董事和核心领导人,BU ADRC与BU和其他地方的调查人员之间的互动,BU
管理,工作人员在NIA,以及地方和国家社区组织。AC整合,协调,
指导和计划所有BU ADRC活动,并确保符合所有人类受试者,科学完整性,
以及NIH的财政政策要求。这包括提供一个有效的结构,以支持我们的科学
努力集中在研究AD/ADRD疾病异质性,确保我们的不同队列的可用性,
支持和实施《国家老年痴呆症计划项目法》的主题和目标。
我们会监察整个发展检讨委员会及其个别核心部分的工作进度,以确保
国家适应行动方案和国家执行机构里程碑和目标的问责制。AC促进创新AD/ADRD研究,
提供有远见的领导,促进跨核心互动,协调提供
资源,以支持合格的研究人员在BU和其他地方,国家和国际研究
程序.咨询委员会促进与地方、区域、国家和国际AD/ADRD的伙伴关系
研究社区支持高影响AD/ADRD研究。AC将确保所有强制数据
以准确和及时的方式向NACC提交生物标本集,并将生物标本提交给
NCRAD。AC确保我们支持并告知我们所服务的社区,
BU ADRC和AD/ADRD研究,并征求他们的反馈和建议。空调在下面
BU ADRC主任Neil Kowall博士直接向BU医学院院长报告。在
他作为BU ADRC主任的角色,由BU ADRC核心组成的执行委员会提供支持
领导人和其他高级思想领袖在BU。其他行政委员会包括一个外部咨询委员会。
委员会、内部咨询委员会和社区行动理事会。与BU ADRC合作
主任,这些委员会负责协调、规划、监督和评估所有BU ADRC
活动,并确保BU ADRC资源的最佳利用。AC管理开发
项目计划,以支持重点放在基础或临床AD/ADRD研究的优秀项目。一
发展项目审查小组将被委托审查,选择和监督这些项目。
将从多个来源征求持续的互动沟通和投入,包括我们的机构
研究社区,外部AD/ADRD专家和NIA,以加强和改善我们中心的
性能
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Neil W. Kowall其他文献
Multi-ancestry genome-wide meta-analysis of 56,241 individuals identifies known and novel cross-population and ancestry-specific associations as novel risk loci for Alzheimer’s disease
- DOI:
10.1186/s13059-025-03564-z - 发表时间:
2025-07-17 - 期刊:
- 影响因子:9.400
- 作者:
Farid Rajabli;Penelope Benchek;Giuseppe Tosto;Nicholas Kushch;Jin Sha;Katrina Bazemore;Congcong Zhu;Wan-Ping Lee;Jacob Haut;Kara L. Hamilton-Nelson;Nicholas R. Wheeler;Yi Zhao;John J. Farrell;Michelle A. Grunin;Yuk Yee Leung;Pavel P. Kuksa;Donghe Li;Eder Lucio da Fonseca;Jesse B. Mez;Ellen L. Palmer;Jagan Pillai;Richard M. Sherva;Yeunjoo E. Song;Xiaoling Zhang;Takeshi Ikeuchi;Taha Iqbal;Omkar Pathak;Otto Valladares;Dolly Reyes-Dumeyer;Amanda B. Kuzma;Erin Abner;Larry D. Adams;Perrie M. Adams;Alyssa Aguirre;Marilyn S. Albert;Roger L. Albin;Mariet Allen;Lisa Alvarez;Liana G. Apostolova;Steven E. Arnold;Sanjay Asthana;Craig S. Atwood;Sanford Auerbach;Gayle Ayres;Clinton T. Baldwin;Robert C. Barber;Lisa L. Barnes;Sandra Barral;Thomas G. Beach;James T. Becker;Gary W. Beecham;Duane Beekly;Bruno A. Benitez;David Bennett;John Bertelson;Thomas D. Bird;Deborah Blacker;Bradley F. Boeve;James D. Bowen;Adam Boxer;James Brewer;James R. Burke;Jeffrey M. Burns;Joseph D. Buxbaum;Nigel J. Cairns;Laura B. Cantwell;Chuanhai Cao;Christopher S. Carlson;Cynthia M. Carlsson;Regina M. Carney;Minerva M. Carrasquillo;Scott Chasse;Marie-Francoise Chesselet;Nathaniel A. Chin;Helena C. Chui;Jaeyoon Chung;Suzanne Craft;Paul K. Crane;David H. Cribbs;Elizabeth A. Crocco;Carlos Cruchaga;Michael L. Cuccaro;Munro Cullum;Eveleen Darby;Barbara Davis;Philip L. De Jager;Charles DeCarli;John DeToledo;Malcolm Dick;Dennis W. Dickson;Beth A. Dombroski;Rachelle S. Doody;Ranjan Duara;NIlüfer Ertekin-Taner;Denis A. Evans;Kelley M. Faber;Thomas J. Fairchild;Kenneth B. Fallon;David W. Fardo;Martin R. Farlow;Victoria Fernandez-Hernandez;Steven Ferris;Robert P. Friedland;Tatiana M. Foroud;Matthew P. Frosch;Brian Fulton-Howard;Douglas R. Galasko;Adriana Gamboa;Marla Gearing;Daniel H. Geschwind;Bernardino Ghetti;John R. Gilbert;Rodney C.P. Go;Alison M. Goate;Thomas J. Grabowski;Neill R. Graff-Radford;Robert C. Green;John H. Growdon;Hakon Hakonarson;James Hall;Ronald L. Hamilton;Oscar Harari;John Hardy;Lindy E. Harrell;Elizabeth Head;Victor W. Henderson;Michelle Hernandez;Timothy Hohman;Lawrence S. Honig;Ryan M. Huebinger;Matthew J. Huentelman;Christine M. Hulette;Bradley T. Hyman;Linda S. Hynan;Laura Ibanez;Gail P. Jarvik;Suman Jayadev;Lee-Way Jin;Kim Johnson;Leigh Johnson;M. Ilyas Kamboh;Anna M. Karydas;Mindy J. Katz;John S. Kauwe;Jeffrey A. Kaye;C. Dirk Keene;Aisha Khaleeq;Masataka Kikuchi;Ronald Kim;Janice Knebl;Neil W. Kowall;Joel H. Kramer;Walter A. Kukull;Frank M. LaFerla;James J. Lah;Eric B. Larson;Alan Lerner;James B. Leverenz;Allan I. Levey;Andrew P. Lieberman;Richard B. Lipton;Mark Logue;Oscar L. Lopez;Kathryn L. Lunetta;Constantine G. Lyketsos;Douglas Mains;Flanagan E. Margaret;Daniel C. Marson;Eden RR. Martin;Frank Martiniuk;Deborah C. Mash;Eliezer Masliah;Paul Massman;Arjun Masurkar;Wayne C. McCormick;Susan M. McCurry;Andrew N. McDavid;Stefan McDonough;Ann C. McKee;Marsel Mesulam;Bruce L. Miller;Carol A. Miller;Joshua W. Miller;Thomas J. Montine;Edwin S. Monuki;John C. Morris;Shubhabrata Mukherjee;Amanda J. Myers;Trung Nguyen;Thomas Obisesan;Sid O’Bryant;John M. Olichney;Marcia Ory;Raymond Palmer;Joseph E. Parisi;Henry L. Paulson;Valory Pavlik;David Paydarfar;Victoria Perez;Elaine Peskind;Ronald C. Petersen;Helen Petrovitch;Aimee Pierce;Marsha Polk;Wayne W. Poon;Huntington Potter;Liming Qu;Mary Quiceno;Joseph F. Quinn;Ashok Raj;Murray Raskind;Eric M. Reiman;Barry Reisberg;Joan S. Reisch;John M. Ringman;Erik D. Roberson;Monica Rodriguear;Ekaterina Rogaeva;Howard J. Rosen;Roger N. Rosenberg;Donald R. Royall;Marwan Sabbagh;A. Dessa Sadovnick;Mark A. Sager;Mary Sano;Andrew J. Saykin;Julie A. Schneider;Lon S. Schneider;William W. Seeley;Susan H. Slifer;Scott Small;Amanda G. Smith;Janet P. Smith;Joshua A. Sonnen;Salvatore Spina;Peter St George-Hyslop;Takiyah D. Starks;Robert A. Stern;Alan B. Stevens;Stephen M. Strittmatter;David Sultzer;Russell H. Swerdlow;Rudolph E. Tanzi;Jeffrey L. Tilson;John Q. Trojanowski;Juan C. Troncoso;Magda Tsolaki;Debby W. Tsuang;Vivianna M. Van Deerlin;Linda J. van Eldik;Jeffery M. Vance;Badri N. Vardarajan;Robert Vassar;Harry V. Vinters;Jean-Paul Vonsattel;Sandra Weintraub;Kathleen A. Welsh-Bohmer;Patrice L. Whitehead;Ellen M. Wijsman;Kirk C. Wilhelmsen;Benjamin Williams;Jennifer Williamson;Henrik Wilms;Thomas S. Wingo;Thomas Wisniewski;Randall L. Woltjer;Martin Woon;Clinton B. Wright;Chuang-Kuo Wu;Steven G. Younkin;Chang-En Yu;Lei Yu;Xiongwei Zhu;Brian W. Kunkle;William S. Bush;Akinori Miyashita;Goldie S. Byrd;Li-San Wang;Lindsay A. Farrer;Jonathan L. Haines;Richard Mayeux;Margaret A. Pericak-Vance;Gerard D. Schellenberg;Gyungah R. Jun;Christiane Reitz;Adam C. Naj - 通讯作者:
Adam C. Naj
Multiomics analysis to explore blood metabolite biomarkers in an Alzheimer’s Disease Neuroimaging Initiative cohort
多组学分析探索阿尔茨海默病神经影像倡议队列中的血液代谢生物标志物
- DOI:
10.1038/s41598-024-56837-1 - 发表时间:
2024 - 期刊:
- 影响因子:4.6
- 作者:
Takaki Oka;Yuki Matsuzawa;Momoka Tsuneyoshi;Yoshitaka Nakamura;Ken Aoshima;H. Tsugawa;Michael Paul Ronald Clifford R. William John Q. Arthur W. Weiner Aisen Petersen Jack Jagust Trojanowki Toga ;Michael Weiner;P. Aisen;Ron Petersen;Clifford R Jack;William Jagust;J. Trojanowki;Arthur W Toga;L. Beckett;Robert C. Green;Andrew J. Saykin;John C. Morris;Leslie M. Shaw;Enchi Liu;T. Montine;R. G. Thomas;Michael Donohue;Sarah Walter;D. Gessert;T. Sather;G. Jiminez;Danielle Harvey;M. Bernstein;Nick Fox;Paul Thompson;N. Schuff;Charlie S. DeCarli;B. Borowski;J. Gunter;Matthew Senjem;P. Vemuri;David Jones;K. Kantarci;C. Ward;Robert A. Koeppe;Norman L. Foster;Eric M Reiman;Kewei Chen;C. Mathis;Susan Landau;Nigel J. Cairns;E. Householder;Lisa Taylor Reinwald;V. Lee;M. Korecka;M. Figurski;K. Crawford;S. Neu;Tatiana M Foroud;S. Potkin;L. Shen;Faber Kelley;Sungeun Kim;K. Nho;Zaven Kachaturian;Richard Frank;Peter J. Snyder;S. Molchan;J. Kaye;Joseph Quinn;B. Lind;R. Carter;S. Dolen;Lon S. Schneider;S. Pawluczyk;Mauricio Beccera;L. Teodoro;B. Spann;J. Brewer;H. Vanderswag;A. Fleisher;J. Heidebrink;J. Lord;S. Mason;C. Albers;D. Knopman;K. Johnson;Rachelle S. Doody;Javier Villanueva Meyer;M. Chowdhury;S. Rountree;M. Dang;Y. Stern;Lawrence S. Honig;Karen L. Bell;B. Ances;John C. Morris;M. Carroll;Sue Leon;E. Householder;M. Mintun;S. Schneider;A. Oliver;D. Marson;R. Griffith;D. Clark;David S Geldmacher;J. Brockington;Erik Roberson;H. Grossman;Effie M. Mitsis;L. de Toledo‐Morrell;R. Shah;R. Duara;D. Varon;Maria T. Greig;Peggy Roberts;Marilyn S. Albert;C. Onyike;D. D’Agostino;S. Kielb;James E. Galvin;D. Pogorelec;Brittany Cerbone;Christina A. Michel;H. Rusinek;Mony J. de Leon;Lidia Glodzik;S. de Santi;P. Doraiswamy;J. Petrella;T. Wong;Steven E. Arnold;J. Karlawish;David A. Wolk;Charles D. Smith;G. Jicha;Peter Hardy;P. Sinha;Elizabeth Oates;G. Conrad;Oscar L. Lopez;M. Oakley;D. Simpson;A. Porsteinsson;B. Goldstein;K. Martin;K. Makino;M. Ismail;C. Brand;R. Mulnard;G. Thai;Catherine Mc Adams Ortiz;Kyle Womack;D. Mathews;M. Quiceno;R. D. Arrastia;Richard D. King;Myron Weiner;K. M. Cook;Michael D. Devous;A. Levey;J. Lah;J. Cellar;Jeffrey M. Burns;H. Anderson;R. Swerdlow;Liana G. Apostolova;K. Tingus;Ellen Woo;Daniel H. S. Silverman;Po H. Lu;G. Bartzokis;Neill R. Graff Radford;F. Parfitt;Tracy Kendall;Heather K. Johnson;Marty Farlow;A. Hake;Brandy R. Matthews;S. Herring;Cynthia Hunt;Christopher H. van Dyck;Richard E. Carson;M. Macavoy;H. Chertkow;Howard Bergman;C. Hosein;S. Black;B. Stefanovic;Curtis Caldwell;G. R. Hsiung;H. Feldman;B. Mudge;M. Assaly;Andrew Kertesz;J. Rogers;D. Trost;C. Bernick;D. Munic;D. Kerwin;M.;K. Lipowski;Chuang‐Kuo Wu;N. Johnson;C. Sadowsky;Walter Martínez;Teresa Villena;R. S. Turner;K. Johnson;B. Reynolds;R. Sperling;Keith A. Johnson;G. Marshall;Meghan T. Frey;Jerome A. Yesavage;Joy Taylor;B. Lane;A. Rosen;Jared S. Tinklenberg;M. Sabbagh;C. Belden;S. Jacobson;Sherye A. Sirrel;Neil W. Kowall;Ronald J Killiany;A. Budson;A. Norbash;P. L. Johnson;T. Obisesan;S. Wolday;Joanne S. Allard;Alan J Lerner;P. Ogrocki;Leon Hudson;E. Fletcher;O. Carmichael;J. Olichney;Charlie S. DeCarli;S. Kittur;Michael Borrie;T. Lee;Rob Bartha;S. Johnson;Sanjay Asthana;C. Carlsson;S. Potkin;Adrian Preda;D. Nguyen;P. Tariot;A. Fleisher;Stephanie A. Reeder;V. Bates;H. Capote;M. Rainka;D. Scharre;M. Kataki;Anahita Adeli;E. Zimmerman;D. Celmins;Alice D. Brown;G. D. Pearlson;K. Blank;K. Anderson;R. Santulli;T. Kitzmiller;Eben S. Schwartz;K. Sink;J. Williamson;P. Garg;F. Watkins;Brian R. Ott;H. Querfurth;G. Tremont;S. Salloway;P. Malloy;Stephen Correia;H. Rosen;Bruce L. Miller;Jacobo Mintzer;K. Spicer;David Bachman;E. Finger;S. Pasternak;I. Rachinsky;J. Rogers;Andrew Kertesz;D. Drost;N. Pomara;R. Hernando;A. Sarrael;Susan K. Schultz;L. Ponto;H. Shim;K. Smith;N. Relkin;G. Chaing;Lisa Raudin;Amanda G. Smith;K. Fargher;B. A. Raj - 通讯作者:
B. A. Raj
VA’s National PTSD Brain Bank: a National Resource for Research
- DOI:
10.1007/s11920-017-0822-6 - 发表时间:
2017-08-25 - 期刊:
- 影响因子:6.700
- 作者:
Matthew J. Friedman;Bertrand R. Huber;Christopher B. Brady;Robert J. Ursano;David M. Benedek;Neil W. Kowall;Ann C. McKee - 通讯作者:
Ann C. McKee
p75NTR Antagonistic Cyclic Peptide Decreases the Size of β Amyloid-Induced Brain Inflammation
- DOI:
10.1007/s10571-008-9298-6 - 发表时间:
2008-09-19 - 期刊:
- 影响因子:4.800
- 作者:
Mina Yaar;Bennet L. Arble;Kenneth B. Stewart;Nazer H. Qureshi;Neil W. Kowall;Barbara A. Gilchrest - 通讯作者:
Barbara A. Gilchrest
Neil W. Kowall的其他文献
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{{ truncateString('Neil W. Kowall', 18)}}的其他基金
Boston University Alzheimer's Disease Research Center
波士顿大学阿尔茨海默病研究中心
- 批准号:
10264287 - 财政年份:2021
- 资助金额:
$ 39.97万 - 项目类别:
VA Biorepository: Gulf War Veterans' Illnesses Biorepository
VA 生物储存库:海湾战争退伍军人疾病生物储存库
- 批准号:
9402030 - 财政年份:2014
- 资助金额:
$ 39.97万 - 项目类别:
Epigenetic mechanisms relevant to the pathogenesis of ALS
ALS发病机制相关的表观遗传机制
- 批准号:
8597391 - 财政年份:2011
- 资助金额:
$ 39.97万 - 项目类别:
Epigenetic mechanisms relevant to the pathogenesis of ALS
ALS发病机制相关的表观遗传机制
- 批准号:
8043487 - 财政年份:2011
- 资助金额:
$ 39.97万 - 项目类别:
Alzheimer's disease translational research training
阿尔茨海默病转化研究培训
- 批准号:
8446333 - 财政年份:2011
- 资助金额:
$ 39.97万 - 项目类别:
Epigenetic mechanisms relevant to the pathogenesis of ALS
ALS发病机制相关的表观遗传机制
- 批准号:
8245574 - 财政年份:2011
- 资助金额:
$ 39.97万 - 项目类别:
Alzheimer's disease translational research training
阿尔茨海默病转化研究培训
- 批准号:
8660258 - 财政年份:2011
- 资助金额:
$ 39.97万 - 项目类别:
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Tipuna 项目:新西兰的代际疗愈、定居者责任和非殖民化参与行动研究
- 批准号:
AH/X008223/1 - 财政年份:2023
- 资助金额:
$ 39.97万 - 项目类别:
Research Grant
Collaborative Research: SaTC: CORE: Small: Accountability for Central Bank Digital Currency
协作研究:SaTC:核心:小型:中央银行数字货币的责任
- 批准号:
2325477 - 财政年份:2023
- 资助金额:
$ 39.97万 - 项目类别:
Continuing Grant
DASS: A Multi-level Collaborative Design Framework for Cross-sovereignty Software Accountability
DASS:跨主权软件责任的多层次协作设计框架
- 批准号:
2317086 - 财政年份:2023
- 资助金额:
$ 39.97万 - 项目类别:
Standard Grant