Alzheimer's disease translational research training

阿尔茨海默病转化研究培训

基本信息

  • 批准号:
    8660258
  • 负责人:
  • 金额:
    $ 27.79万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    2011
  • 资助国家:
    美国
  • 起止时间:
    2011-05-01 至 2016-04-30
  • 项目状态:
    已结题

项目摘要

DESCRIPTION (provided by applicant): This interdisciplinary post-doctoral training program will provide intensive, structured translational research training in Alzheimer's disease (AD) for a new cadre of talented basic PhD, clinical PhD, and physician scientists. Leveraging the existing infrastructure and research strengths of the NIA-funded Boston University Alzheimer's Disease Center and affiliated faculty, the program will eliminate barriers in communication, knowledge, and collaboration between basic and clinical scientists and train investigators to cross disciplinary boundaries at an early and formative period in their professional development. Through individualized and group didactics, the fellowship program will provide (1) integrated knowledge in the basic and clinical fundamentals of AD, focusing on environmental and genetic risk factors, prevention, mechanistic pathways, biomarkers, diagnostics, and therapeutics of AD, (2) training in essential research skills (e.g., conceptualization, development, and implementation of research studies, and creativity in developing new research directions), (3) training in critical professional skills for success in academic medicine (e.g., understanding available funding mechanisms and development of grant writing skills, oral presentation skills, and manuscript writing abilities), (4) training in the responsible conduct of research, emphasizing both animal and human subjects, and (5) a high quality jointly-mentored, interdisciplinary research experience that synthesizes the trainee's knowledge base, research and professional skill set, and appreciation of responsible conduct of research, and prepares the trainee for independence as an investigator. Trainees completing the program will be well-positioned for academic success in both conducting and securing funding for original research in AD. As a consequence, the program will fill an important need for an increased number of high quality investigators who are well equipped to advance the field of AD prevention, diagnostics, and therapeutics.
描述(由申请人提供):这项跨学科的博士后培训计划将为阿尔茨海默氏病(AD)提供深入的,结构化的转化研究培训,为新的才华横溢的基本博士学位,临床博士和医师科学家提供。该计划利用NIA资助的波士顿大学阿尔茨海默氏病中心和附属学院的现有基础设施和研究优势,该计划将消除基础和临床科学家的沟通,知识和合作障碍,并在早期和形成性的职业发展中进行跨学科界限之间的跨学科界限。 Through individualized and group didactics, the fellowship program will provide (1) integrated knowledge in the basic and clinical fundamentals of AD, focusing on environmental and genetic risk factors, prevention, mechanistic pathways, biomarkers, diagnostics, and therapeutics of AD, (2) training in essential research skills (e.g., conceptualization, development, and implementation of research studies, and creativity in developing new research directions), (3) training in critical professional skills for success in学术医学(例如,了解可用的资助机制和赠款写作技巧,口头表现能力和手稿写作能力的发展),(4)在负责任的研究中进行培训,强调动物和人类受试者,以及(5)高质量的共同致力于的,跨学科的研究经验,综合了培训者的知识基础,研究和专业的研究人员,并构成了培训的培训,并准备了培训,并准备了培训,并准备了培训,并准备了培训,并准备工作,并准备了培训,并准备了培训。完成该计划的学员将在进行和获得AD原始研究资金方面的学术成功方面具有很好的态度。结果,该计划将满足越来越多的高质量研究人员的重要需求,这些调查员有能力提高预防广告,诊断和治疗学领域。

项目成果

期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)

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Neil W. Kowall其他文献

Multiomics analysis to explore blood metabolite biomarkers in an Alzheimer’s Disease Neuroimaging Initiative cohort
多组学分析探索阿尔茨海默病神经影像倡议队列中的血液代谢生物标志物
  • DOI:
    10.1038/s41598-024-56837-1
  • 发表时间:
    2024
  • 期刊:
  • 影响因子:
    4.6
  • 作者:
    Takaki Oka;Yuki Matsuzawa;Momoka Tsuneyoshi;Yoshitaka Nakamura;Ken Aoshima;H. Tsugawa;Michael Paul Ronald Clifford R. William John Q. Arthur W. Weiner Aisen Petersen Jack Jagust Trojanowki Toga ;Michael Weiner;P. Aisen;Ron Petersen;Clifford R Jack;William Jagust;J. Trojanowki;Arthur W Toga;L. Beckett;Robert C. Green;Andrew J. Saykin;John C. Morris;Leslie M. Shaw;Enchi Liu;T. Montine;R. G. Thomas;Michael Donohue;Sarah Walter;D. Gessert;T. Sather;G. Jiminez;Danielle Harvey;M. Bernstein;Nick Fox;Paul Thompson;N. Schuff;Charlie S. DeCarli;B. Borowski;J. Gunter;Matthew Senjem;P. Vemuri;David Jones;K. Kantarci;C. Ward;Robert A. Koeppe;Norman L. Foster;Eric M Reiman;Kewei Chen;C. Mathis;Susan Landau;Nigel J. Cairns;E. Householder;Lisa Taylor Reinwald;V. Lee;M. Korecka;M. Figurski;K. Crawford;S. Neu;Tatiana M Foroud;S. Potkin;L. Shen;Faber Kelley;Sungeun Kim;K. Nho;Zaven Kachaturian;Richard Frank;Peter J. Snyder;S. Molchan;J. Kaye;Joseph Quinn;B. Lind;R. Carter;S. Dolen;Lon S. Schneider;S. Pawluczyk;Mauricio Beccera;L. Teodoro;B. Spann;J. Brewer;H. Vanderswag;A. Fleisher;J. Heidebrink;J. Lord;S. Mason;C. Albers;D. Knopman;K. Johnson;Rachelle S. Doody;Javier Villanueva Meyer;M. Chowdhury;S. Rountree;M. Dang;Y. Stern;Lawrence S. Honig;Karen L. Bell;B. Ances;John C. Morris;M. Carroll;Sue Leon;E. Householder;M. Mintun;S. Schneider;A. Oliver;D. Marson;R. Griffith;D. Clark;David S Geldmacher;J. Brockington;Erik Roberson;H. Grossman;Effie M. Mitsis;L. de Toledo‐Morrell;R. Shah;R. Duara;D. Varon;Maria T. Greig;Peggy Roberts;Marilyn S. Albert;C. Onyike;D. D’Agostino;S. Kielb;James E. Galvin;D. Pogorelec;Brittany Cerbone;Christina A. Michel;H. Rusinek;Mony J. de Leon;Lidia Glodzik;S. de Santi;P. Doraiswamy;J. Petrella;T. Wong;Steven E. Arnold;J. Karlawish;David A. Wolk;Charles D. Smith;G. Jicha;Peter Hardy;P. Sinha;Elizabeth Oates;G. Conrad;Oscar L. Lopez;M. Oakley;D. Simpson;A. Porsteinsson;B. Goldstein;K. Martin;K. Makino;M. Ismail;C. Brand;R. Mulnard;G. Thai;Catherine Mc Adams Ortiz;Kyle Womack;D. Mathews;M. Quiceno;R. D. Arrastia;Richard D. King;Myron Weiner;K. M. Cook;Michael D. Devous;A. Levey;J. Lah;J. Cellar;Jeffrey M. Burns;H. Anderson;R. Swerdlow;Liana G. Apostolova;K. Tingus;Ellen Woo;Daniel H. S. Silverman;Po H. Lu;G. Bartzokis;Neill R. Graff Radford;F. Parfitt;Tracy Kendall;Heather K. Johnson;Marty Farlow;A. Hake;Brandy R. Matthews;S. Herring;Cynthia Hunt;Christopher H. van Dyck;Richard E. Carson;M. Macavoy;H. Chertkow;Howard Bergman;C. Hosein;S. Black;B. Stefanovic;Curtis Caldwell;G. R. Hsiung;H. Feldman;B. Mudge;M. Assaly;Andrew Kertesz;J. Rogers;D. Trost;C. Bernick;D. Munic;D. Kerwin;M.;K. Lipowski;Chuang‐Kuo Wu;N. Johnson;C. Sadowsky;Walter Martínez;Teresa Villena;R. S. Turner;K. Johnson;B. Reynolds;R. Sperling;Keith A. Johnson;G. Marshall;Meghan T. Frey;Jerome A. Yesavage;Joy Taylor;B. Lane;A. Rosen;Jared S. Tinklenberg;M. Sabbagh;C. Belden;S. Jacobson;Sherye A. Sirrel;Neil W. Kowall;Ronald J Killiany;A. Budson;A. Norbash;P. L. Johnson;T. Obisesan;S. Wolday;Joanne S. Allard;Alan J Lerner;P. Ogrocki;Leon Hudson;E. Fletcher;O. Carmichael;J. Olichney;Charlie S. DeCarli;S. Kittur;Michael Borrie;T. Lee;Rob Bartha;S. Johnson;Sanjay Asthana;C. Carlsson;S. Potkin;Adrian Preda;D. Nguyen;P. Tariot;A. Fleisher;Stephanie A. Reeder;V. Bates;H. Capote;M. Rainka;D. Scharre;M. Kataki;Anahita Adeli;E. Zimmerman;D. Celmins;Alice D. Brown;G. D. Pearlson;K. Blank;K. Anderson;R. Santulli;T. Kitzmiller;Eben S. Schwartz;K. Sink;J. Williamson;P. Garg;F. Watkins;Brian R. Ott;H. Querfurth;G. Tremont;S. Salloway;P. Malloy;Stephen Correia;H. Rosen;Bruce L. Miller;Jacobo Mintzer;K. Spicer;David Bachman;E. Finger;S. Pasternak;I. Rachinsky;J. Rogers;Andrew Kertesz;D. Drost;N. Pomara;R. Hernando;A. Sarrael;Susan K. Schultz;L. Ponto;H. Shim;K. Smith;N. Relkin;G. Chaing;Lisa Raudin;Amanda G. Smith;K. Fargher;B. A. Raj
  • 通讯作者:
    B. A. Raj
Case 7-1988
案例7-1988
  • DOI:
  • 发表时间:
    1988
  • 期刊:
  • 影响因子:
    0
  • 作者:
    Neil W. Kowall;R. A. Sobel
  • 通讯作者:
    R. A. Sobel
Elevation of endoplasmic reticulum (ER) stress-mediated Ca<sup>2+</sup> release leads to tauopathy in chronic traumatic encephalopathy (CTE)
  • DOI:
    10.1016/j.ibror.2019.07.295
  • 发表时间:
    2019-09-01
  • 期刊:
  • 影响因子:
  • 作者:
    Hyeonjoo Im;Yunha Kim;Sung Soo Im;Yun Kyung Kim;Seung Jae Hyeon;Junghee Lee;Neil W. Kowall;Sooyoung Chung;Ann C. Mckee;Hoon Ryu
  • 通讯作者:
    Hoon Ryu
Impaired EWSR1 activity leads to oligodendrocyte dysfunction and demyelination of motor neurons in amyotrophic lateral sclerosis (ALS)
  • DOI:
    10.1016/j.ibror.2019.07.371
  • 发表时间:
    2019-09-01
  • 期刊:
  • 影响因子:
  • 作者:
    Mi-Hyun Choi;Phuong T. Nguyen;Eunmi Kim;Hyun Soo Shim;Seung Jae Hyeon;Yun Ha Kim;Yu Jin Hwang;Neil W. Kowall;Sean Bong Lee;Junghee Lee;Hae-Chul Park;Hoon Ryu
  • 通讯作者:
    Hoon Ryu

Neil W. Kowall的其他文献

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{{ truncateString('Neil W. Kowall', 18)}}的其他基金

Boston University Alzheimer's Disease Research Center
波士顿大学阿尔茨海默病研究中心
  • 批准号:
    10264287
  • 财政年份:
    2021
  • 资助金额:
    $ 27.79万
  • 项目类别:
Core A: Administrative Core
核心A:行政核心
  • 批准号:
    10468306
  • 财政年份:
    2021
  • 资助金额:
    $ 27.79万
  • 项目类别:
Core A: Administrative Core
核心A:行政核心
  • 批准号:
    10264288
  • 财政年份:
    2021
  • 资助金额:
    $ 27.79万
  • 项目类别:
Core A: Administrative Core
核心A:行政核心
  • 批准号:
    10652549
  • 财政年份:
    2021
  • 资助金额:
    $ 27.79万
  • 项目类别:
VA Biorepository Brain Bank
VA 生物储存库脑库
  • 批准号:
    8661513
  • 财政年份:
    2014
  • 资助金额:
    $ 27.79万
  • 项目类别:
VA Biorepository: Gulf War Veterans' Illnesses Biorepository
VA 生物储存库:海湾战争退伍军人疾病生物储存库
  • 批准号:
    9402030
  • 财政年份:
    2014
  • 资助金额:
    $ 27.79万
  • 项目类别:
Epigenetic mechanisms relevant to the pathogenesis of ALS
ALS发病机制相关的表观遗传机制
  • 批准号:
    8597391
  • 财政年份:
    2011
  • 资助金额:
    $ 27.79万
  • 项目类别:
Alzheimer's disease translational research training
阿尔茨海默病转化研究培训
  • 批准号:
    8446333
  • 财政年份:
    2011
  • 资助金额:
    $ 27.79万
  • 项目类别:
Epigenetic mechanisms relevant to the pathogenesis of ALS
ALS发病机制相关的表观遗传机制
  • 批准号:
    8043487
  • 财政年份:
    2011
  • 资助金额:
    $ 27.79万
  • 项目类别:
Epigenetic mechanisms relevant to the pathogenesis of ALS
ALS发病机制相关的表观遗传机制
  • 批准号:
    8245574
  • 财政年份:
    2011
  • 资助金额:
    $ 27.79万
  • 项目类别:

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揭示 ADRD 中种族不平等的机制:心理社会风险和白质完整性的弹性因素
  • 批准号:
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The Influence of Lifetime Occupational Experience on Cognitive Trajectories Among Mexican Older Adults
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Fluency from Flesh to Filament: Collation, Representation, and Analysis of Multi-Scale Neuroimaging data to Characterize and Diagnose Alzheimer's Disease
从肉体到细丝的流畅性:多尺度神经影像数据的整理、表示和分析,以表征和诊断阿尔茨海默病
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    $ 27.79万
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