Alzheimer's disease translational research training

阿尔茨海默病转化研究培训

• 批准号: 8446333
• 负责人: Neil W. Kowall
• 金额: $ 27.83万
• 依托单位: BOSTON UNIVERSITY MEDICAL CAMPUS
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-05-01 至 2016-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8446333
• 关键词: Alzheimer' s Disease; Research Training; Translational Research

DESCRIPTION (provided by applicant): This interdisciplinary post-doctoral training program will provide intensive, structured translational research training in Alzheimer's disease (AD) for a new cadre of talented basic PhD, clinical PhD, and physician scientists. Leveraging the existing infrastructure and research strengths of the NIA-funded Boston University Alzheimer's Disease Center and affiliated faculty, the program will eliminate barriers in communication, knowledge, and collaboration between basic and clinical scientists and train investigators to cross disciplinary boundaries at an early and formative period in their professional development. Through individualized and group didactics, the fellowship program will provide (1) integrated knowledge in the basic and clinical fundamentals of AD, focusing on environmental and genetic risk factors, prevention, mechanistic pathways, biomarkers, diagnostics, and therapeutics of AD, (2) training in essential research skills (e.g., conceptualization, development, and implementation of research studies, and creativity in developing new research directions), (3) training in critical professional skills for success in academic medicine (e.g., understanding available funding mechanisms and development of grant writing skills, oral presentation skills, and manuscript writing abilities), (4) training in the responsible conduct of research, emphasizing both animal and human subjects, and (5) a high quality jointly-mentored, interdisciplinary research experience that synthesizes the trainee's knowledge base, research and professional skill set, and appreciation of responsible conduct of research, and prepares the trainee for independence as an investigator. Trainees completing the program will be well-positioned for academic success in both conducting and securing funding for original research in AD. As a consequence, the program will fill an important need for an increased number of high quality investigators who are well equipped to advance the field of AD prevention, diagnostics, and therapeutics.

描述（由申请人提供）：这个跨学科的博士后培训项目将为一批有才华的基础博士、临床博士和医师科学家提供关于阿尔茨海默病（AD）的强化、结构化转化研究培训。该项目将利用 NIA 资助的波士顿大学阿尔茨海默病中心及其附属教员的现有基础设施和研究优势，消除基础科学家和临床科学家之间的沟通、知识和合作障碍，并培训研究人员在专业发展的早期和形成期跨越学科界限。通过个性化和小组教学，该奖学金计划将提供（1）AD基础和临床基础的综合知识，重点是AD的环境和遗传风险因素、预防、机制途径、生物标志物、诊断和治疗，（2）基本研究技能的培训（例如，研究的概念化、发展和实施，以及开发新研究方向的创造力），（3）关键专业技能的培训，以取得成功 学术医学（例如，了解现有的资助机制和发展拨款写作技能、口头表达技巧和手稿写作能力），（4）负责任地进行研究的培训，强调动物和人类受试者，以及（5）高质量的联合指导、跨学科研究经验，综合受训者的知识基础、研究和专业技能，以及对负责任的研究行为的欣赏，并为受训者独立作为研究者做好准备。完成该项目的学员将能够在开展 AD 原创研究并获得资金方面取得学术成功。因此，该计划将满足对更多高质量研究人员的重要需求，这些研究人员有能力推进 AD 预防、诊断和治疗领域的发展。