HEALTH OUTREACH PROGRAM FOR THE ELDERLY (HOPE)

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目及 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 BU阿尔茨海默病中心（BU ADC）是美国国立卫生研究院资助的32个中心之一，负责提供与阿尔茨海默病（AD）相关的研究，教育和临床护理。BU ADC由5个核心组成：行政，临床，教育和信息传递，神经病理学和小鼠育种。研究，教育和临床护理的功能是在五个核心之一的主持下完成的。核心支持几个重点或感兴趣的领域：AD的遗传和环境风险，晚期痴呆症，家庭和专业护理以及涉及非裔美国人的研究。NIH最近重新资助了BU ADC，从2001年7月开始为期五年。 BU ADC临床核心的主要目的是通过提供来自非卧床和晚期人群的特征良好的患者、对照和护理人员人群的信息和材料，促进BU的AD研究。BU ADC建立了一个名为临床核心的患者/对照登记研究的登记研究。 它由痴呆症患者和认知正常的参与者组成。 登记的患者和对照组每年进行一次标准化的神经系统检查和神经心理测试。采集并储存血液用于分子遗传学研究。详细的医疗，社会和家族史也被获得。将该信息输入数据库，用于纵向比较和与AD进展及其对护理人员的影响的相关性。受试者、数据和血液/DNA可供研究人员使用，以刺激对AD和正常衰老的新研究。 .

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The BU Alzheimer's Disease Center (BU ADC) is one of 32 NIH funded centers mandated to provide research, education and clinical care related to Alzheimer's disease (AD). The BU ADC is comprised of 5 Cores: Administrative, Clinical, Education and Information Transfer, Neuropathology and Murine Breeding. The functions of research, education and clinical care are accomplished under the auspices of one of the five Cores. The Cores support several areas of emphasis or interest: genetic and environmental risks for AD, late stage dementia, family and professional care giving and studies involving African Americans. NIH has recently re-funded the BU ADC for a five years beginning July 2001. The primary purpose of the Clinical Core of the BU ADC is to promote research on AD at BU by providing information and materials from well characterized patient, control, and caregiver populations drawn from ambulatory and late-stage populations. The BU ADC has established a Registry called the Patient/Control Registry of the Clinical Core. It is comprised of participants with dementia and participants with normal cognition. Patients and controls enrolled in the Registry are assessed annually with a standardized neurological examination and neurophsychological test battery. Blood is obtained and stored for molecular genetic studies. A detailed medical, social, and family history is also obtained. This information is entered into a database for longitudinal comparisons and correlation with the progression of AD and its impact on caregivers. Subjects, data, and blood/DNA are made available to researchers to stimulate new research in AD and normal aging. .