New York Regional Center for Diabetes Translation Research

纽约糖尿病翻译研究区域中心

基本信息

  • 批准号:
    10480947
  • 负责人:
  • 金额:
    $ 9.82万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    2016
  • 资助国家:
    美国
  • 起止时间:
    2016-09-20 至 2026-07-31
  • 项目状态:
    未结题

项目摘要

Life Course Methodology Core The overall goal of the Life Course Methodology Core (LCMC) of the New York Regional Center for Diabetes Translation Research is to support high quality type 2 translational research in diabetes prevention and control across the life span. The life course perspective focuses on the biopsychosocial and behavioral processes that individuals experience during particular periods in their life, and examines the interplay between these exposures in shaping disease risk. Currently, there is strong evidence from observational studies that the processes that lead to the development of diabetes start early in life and continue throughout the lifespan. This life course approach also can enhance the translation of efficacious interventions by ensuring that intervention strategies are appropriate for the age group targeted and address associated individual or environmental barriers. Following this line of thought, we propose a two pronged approach that identifies the most relevant modifiable risk factors and the most appropriate interventions taking into account the life stage targeted. The LCMC will leverage existing multidisciplinary expertise and infrastructure to facilitate application of a life course perspective to new translational diabetes research. Einstein investigators and their collaborators have accumulated decades of expertise in diabetes research across the life span and are well positioned to contribute to the acceleration of translational research. The LCMC will provide conceptual and instrumental support regarding the design, and implementation of new translational diabetes research across the life span with the ultimate goal of decreasing the burden of diabetes and alleviating diabetes health disparities. The LCMC specific aims are: 1) To build capacity in using the life course approach to the design of new translational diabetes research; 2) To facilitate the implementation of new translational diabetes research; 3) To provide consultation and mentorship on biological factors underlying diabetes health disparities across the lifespan.
生命历程方法论核心 纽约区域中心生命历程方法核心(LCMC)的总体目标是 糖尿病转化研究是支持高质量的2型糖尿病预防转化研究 和控制整个生命周期。生命历程的观点侧重于生物心理社会和行为 个人在其生活中的特定时期所经历的过程,并检查 这些暴露在形成疾病风险。目前,观察性研究的有力证据表明, 导致糖尿病发展的过程在生命早期开始并持续整个生命周期。这 生命过程方法还可以通过确保干预措施 战略适合于目标年龄组,并针对相关个人或环境 隔栏.按照这一思路,我们提出了一个双管齐下的方法,确定最相关的 可改变的风险因素和考虑到所针对的生命阶段的最适当干预措施。的 LCMC将利用现有的多学科专业知识和基础设施,以促进生命历程的应用 新的转化糖尿病研究的前景。爱因斯坦的研究人员和他们的合作者 在整个生命周期中积累了数十年的糖尿病研究专业知识, 有助于加速转化研究。LCMC将提供概念和工具 支持在整个生命周期内设计和实施新的转化型糖尿病研究 其最终目标是减少糖尿病的负担和缓解糖尿病健康差距。的 LCMC的具体目标是:1)建立使用生命过程方法设计新产品的能力 转化型糖尿病研究; 2)促进新的转化型糖尿病研究的实施; 3) 提供有关糖尿病健康差异背后的生物学因素的咨询和指导, 寿命

项目成果

期刊论文数量(0)
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Carmen R. Isasi其他文献

Genetic ancestry influences gene-environment interactions with sociocultural factors: Results from the Hispanic Community Health Study/Study of Latinos
遗传血统影响基因 - 环境与社会文化因素的相互作用:西班牙裔社区健康研究/拉丁裔研究的结果
  • DOI:
    10.1016/j.xhgg.2025.100451
  • 发表时间:
    2025-07-10
  • 期刊:
  • 影响因子:
    3.600
  • 作者:
    Jayati Sharma;Cristin E. McArdle;Mariaelisa Graff;Christina Cordero;Martha Daviglus;Linda C. Gallo;Carmen R. Isasi;Tanika N. Kelly;Krista M. Perreira;Gregory A. Talavera;Jianwen Cai;Kari E. North;Lindsay Fernández-Rhodes;Genevieve L. Wojcik
  • 通讯作者:
    Genevieve L. Wojcik
Evolving Science on Cardiovascular Disease Among Hispanic/Latino Adults: emJACC/em International
关于西班牙裔/拉丁裔成年人心血管疾病的不断发展的科学:emJACC/em 国际
  • DOI:
    10.1016/j.jacc.2023.02.023
  • 发表时间:
    2023-04-18
  • 期刊:
  • 影响因子:
    22.300
  • 作者:
    Amber Pirzada;Jianwen Cai;Gerardo Heiss;Daniela Sotres-Alvarez;Linda C. Gallo;Marston E. Youngblood;M. Larissa Avilés-Santa;Hector M. González;Carmen R. Isasi;Robert Kaplan;John Kunz;James P. Lash;David J. Lee;Maria M. Llabre;Frank J. Penedo;Carlos J. Rodriguez;Neil Schneiderman;Tamar Sofer;Gregory A. Talavera;Bharat Thyagarajan;Martha L. Daviglus
  • 通讯作者:
    Martha L. Daviglus
Multi-ancestry genome-wide association analyses incorporating SNP-by-psychosocial interactions identify novel loci for serum lipids
纳入 SNP 与心理社会因素相互作用的多祖先全基因组关联分析确定了血清脂质的新位点
  • DOI:
    10.1038/s41398-025-03418-z
  • 发表时间:
    2025-06-20
  • 期刊:
  • 影响因子:
    6.200
  • 作者:
    Amy R. Bentley;Michael R. Brown;Solomon K. Musani;Karen L. Schwander;Thomas W. Winkler;Mario Sims;Tuomas O. Kilpeläinen;Hugues Aschard;Traci M. Bartz;Lawrence F. Bielak;Jin-Fang Chai;Kumaraswamy Naidu Chitrala;Nora Franceschini;Mariaelisa Graff;Xiuqing Guo;Fernando P. Hartwig;Andrea R.V.R. Horimoto;Elise Lim;Yongmei Liu;Alisa K. Manning;Ilja M. Nolte;Raymond Noordam;Melissa A. Richard;Albert V. Smith;Yun Ju Sung;Dina Vojinovic;Rujia Wang;Yujie Wang;Mary F. Feitosa;Sarah E. Harris;Leo-Pekka Lyytikäinen;Giorgio Pistis;Rainer Rauramaa;Peter J. van der Most;Erin Ware;Stefan Weiss;Wanqing Wen;Lisa R. Yanek;Dan E. Arking;Donna K. Arnett;Christie Ballantyne;Eric Boerwinkle;Yii-Der Ida Chen;Martha L. Daviglus;Lisa de las Fuentes;Paul S. de Vries;Joseph A. C. Delaney;Amanda M. Fretts;Lynette Ekunwe;Jessica D. Faul;Linda C. Gallo;Sami Heikkinen;Georg Homuth;M. Arfan Ikram;Carmen R. Isasi;Jost Bruno Jonas;Liisa Keltikangas-Järvinen;Pirjo Komulainen;Aldi T. Kraja;Jose E. Krieger;Lenore Launer;Jianjun Liu;Kurt Lohman;Annemarie I. Luik;Ani W. Manichaikul;Pedro Marques-Vidal;Yuri Milaneschi;Stanford E. Mwasongwe;Jeffrey R. O’Connell;Kenneth Rice;Stephen S. Rich;Pamela J. Schreiner;Lars Schwettmann;James M. Shikany;Xiao-ou Shu;Jennifer A. Smith;Harold Snieder;Nona Sotoodehnia;E. Shyong Tai;Kent D. Taylor;Lesley Tinker;Michael Y. Tsai;André G. Uitterlinden;Cornelia M. van Duijn;Diana van Heemst;Melanie Waldenberger;Robert B. Wallace;Hwee-Lin Wee;David R. Weir;Wen-Bin Wei;Ko Willems van Dijk;Gregory Wilson;Jie Yao;Kristin L. Young;Xiaoyu Zhang;Wei Zhao;Xiaofeng Zhu;Alan B. Zonderman;Ian J. Deary;Christian Gieger;Hans Jörgen Grabe;Timo A. Lakka;Terho Lehtimäki;Albertine J. Oldehinkel;Martin Preisig;Ya-Xing Wang;Wei Zheng;Michele K. Evans;Michael Province;James Gauderman;Vilmundur Gudnason;Catharina A. Hartman;Bernardo L. Horta;Sharon L. R. Kardia;Charles Kooperberg;Ching-Ti Liu;Dennis O. Mook-Kanamori;Brenda WJH Penninx;Alexandre C. Pereira;Patricia A. Peyser;Bruce M. Psaty;Jerome I. Rotter;Xueling Sim;Kari E. North;Dabeeru C. Rao;Laura Bierut;Clint L. Miller;Alanna C. Morrison;Charles N. Rotimi;Myriam Fornage;Ervin R. Fox
  • 通讯作者:
    Ervin R. Fox
Profiles of Structural Violence in Hispanic/Latino Immigrant and Non-Immigrant Parents: the Hispanic Community Health Study/Study of Latinos (HCHS/SOL) Youth Study
  • DOI:
    10.1007/s10903-025-01707-9
  • 发表时间:
    2025-06-18
  • 期刊:
  • 影响因子:
    1.800
  • 作者:
    Kristine Molina;Kevin Tan;Jinsong Chen;Ramon Durazo-Arvizu;Linda C. Gallo;Krista M. Perreira;Lisa Sanchez-Johnsen;Donglin Zeng;Elizabeth Pulgaron;Alan Delamater;Sage Kim;Paula G. Allen-Meares;Martha L. Daviglus;Carmen R. Isasi;Rosalba Hernandez
  • 通讯作者:
    Rosalba Hernandez
216. Plasma ATN Biomarkers and Brain Measures Among Hispanics/Latinos Across Depressive Symptom Severity: Findings From the Study of Latinos-Investigation of Neurocognitive Aging (HCHS/SOL)
216. 不同抑郁症状严重程度的西班牙裔/拉丁裔人群中的血浆急性肾小管坏死(ATN)生物标志物和脑部指标:拉丁裔神经认知老化研究(HCHS/SOL)的发现
  • DOI:
    10.1016/j.biopsych.2025.02.453
  • 发表时间:
    2025-05-01
  • 期刊:
  • 影响因子:
    9.000
  • 作者:
    Natasha Z. Anita;Ariana M. Stickel;Kevin A. Gonzalez;Carmen R. Isasi;Paola Filigrana;Christian Agudelo;Sonya S. Kaur;Melissa Lamar;Linda C. Gallo;Wassim Tarraf;Douglas Galasko;Hector M. Gonzalez
  • 通讯作者:
    Hector M. Gonzalez

Carmen R. Isasi的其他文献

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{{ truncateString('Carmen R. Isasi', 18)}}的其他基金

Metabolic, behavioral and social determinants of youth-onset T2D
青年发病 T2D 的代谢、行为和社会决定因素
  • 批准号:
    10583215
  • 财政年份:
    2023
  • 资助金额:
    $ 9.82万
  • 项目类别:
Social Stress, Epigenetics and Cardiometabolic Health Among Youth
青少年的社会压力、表观遗传学和心脏代谢健康
  • 批准号:
    10569070
  • 财政年份:
    2021
  • 资助金额:
    $ 9.82万
  • 项目类别:
Social Stress, Epigenetics and Cardiometabolic Health Among Youth
青少年的社会压力、表观遗传学和心脏代谢健康
  • 批准号:
    10406242
  • 财政年份:
    2021
  • 资助金额:
    $ 9.82万
  • 项目类别:
New York Regional Center for Diabetes Translation Research
纽约糖尿病翻译研究区域中心
  • 批准号:
    10290456
  • 财政年份:
    2016
  • 资助金额:
    $ 9.82万
  • 项目类别:
New York Regional Center for Diabetes Translation Research
纽约糖尿病翻译研究区域中心
  • 批准号:
    10704646
  • 财政年份:
    2016
  • 资助金额:
    $ 9.82万
  • 项目类别:
New York Regional Center for Diabetes Translation Research
纽约糖尿病翻译研究区域中心
  • 批准号:
    10290454
  • 财政年份:
    2016
  • 资助金额:
    $ 9.82万
  • 项目类别:
New York Regional Center for Diabetes Translation Research
纽约糖尿病翻译研究区域中心
  • 批准号:
    10480956
  • 财政年份:
    2016
  • 资助金额:
    $ 9.82万
  • 项目类别:
New York Regional Center for Diabetes Translation Research
纽约糖尿病翻译研究区域中心
  • 批准号:
    10704644
  • 财政年份:
    2016
  • 资助金额:
    $ 9.82万
  • 项目类别:
The role of self-control on adolescents' diet and exercise behaviors
自我控制对青少年饮食和运动行为的作用
  • 批准号:
    7314056
  • 财政年份:
    2007
  • 资助金额:
    $ 9.82万
  • 项目类别:
The role of self-control on adolescents' diet and exercise behaviors
自我控制对青少年饮食和运动行为的作用
  • 批准号:
    7497163
  • 财政年份:
    2007
  • 资助金额:
    $ 9.82万
  • 项目类别:

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