Pharmacological Sciences Training Program (PSTP)

药理科学培训计划（PSTP）

• 批准号: 10491483
• 负责人: Patrick Alexander Forcelli
• 金额: $ 15.61万
• 依托单位: GEORGETOWN UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-07-01 至 2027-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10491483
• 关键词: Pharmacology; Science; Training Programs

Project Summary The Pharmacological Sciences Training Program (PSTP) at Georgetown University Medical Center is new, interdisciplinary and integrated program that will bring together an inclusive and diverse community of doctoral candidates across Ph.D. disciplines who are dedicated to thesis research in pharmacological science. Faculty mentors in the PSTP share major research strengths in identifying drug targets within cellular signaling pathways to treat human disease. The 28 mentor and 11 preceptor faculty in the program all have a strong history of mentorship and research programs in drug development for disease treatment with >$30 million in annual research funding. Trainees in the program are drawn from Ph.D. programs in Pharmacology & Physiology, Biochemistry, Tumor Biology, and Neuroscience. Trainees will prepare for future careers in academia, pharma or biotechnology industry, or drug regulatory agencies. This application seeks annual funding for six predoctoral students, providing a catalyst to bring together the four feeder programs, and would be the only NIGMS T32 at GU. Trainees will enter the program in their second year of graduate school, will be supported for their second and third years, and will have ongoing participation throughout the remainder of their degree. Trainees take a comprehensive set of core courses in pharmacological sciences, physiological/biochemical principles integral to pharmacology, and specialized electives in pharmacology relevant to their research. Recognizing the interdisciplinary nature of pharmacological sciences, students will have additional exposure to bioinformatics, molecular and cellular biology, and biostatistics that integrate pharmacology. Our courses take a wide view ranging from cellular networks to organ function to behavior and systems medicine. Training will enhance their understanding of drug mechanisms specific to their field of study and research, and enable them to characterize novel drug targets and signaling pathways in disease. Both trainees and mentors will participate in structured mentor training. During the period of support, all trainees will have two dedicated blocks for internships: one part- time, semester-long placement will occur at Georgetown (e.g., regulatory affairs, technology commercialization); the second block will be summer internship at a local partnering institution (biotech, government, foundations). Thus, our trainees will gain broad exposure to transferable skills across career paths while developing their research abilities. We have set program goals to include (1) achieving a 95% degree attainment within 5.5 years of matriculation, (2) achieving 30% representation of underrepresented groups in our trainee pool, (3) achieving 100% participation of mentors and trainees in formal mentor training, (4) achieving four high-impact publications per trainee, (5) achieve 75% job placement in pharmacology-related careers within two years of degree, (6) continuing to expand our internship opportunities, and (7) increasing the adoption of best practices in graduate admissions. We are committed to training the next generation of pharmacological scientists, building on the strengths of Georgetown’s long track record of success in pharmacology.

项目摘要 乔治敦大学医学中心的药理学培训计划（PSTP）是新的 跨学科和综合计划将汇集一个包容性的博士学位社区 博士学位的候选人致力于制药科学论文研究的学科。学院 PSTP中的导师在识别细胞信号传导途径中的药物目标方面具有主要的研究优势 治疗人类疾病。该计划中的28位导师和11位教职员工都有很强的历史 每年> 3000万美元的疾病治疗药物开发研究计划 研究资金。该计划的学员来自博士学位。药理学与生理学计划， 生物化学，肿瘤生物学和神经科学。学员将为学术界的未来职业做准备 或生物技术行业或药物调节机构。该申请寻求六个五次冠军的年度资金 学生提供催化剂将四个馈线计划汇总在一起，并且将是唯一的Nigms T32 古。学员将在研究生院的第二年进入该计划，第二年将得到支持 和第三年，并将在其剩余学位的其余学位上进行持续的参与。学员接受 药物科学的核心课程综合课程，物理/生化原理不可或缺 药理学和药理学专业选修课与他们的研究相关。认识到 药物科学的跨学科性质，学生将有更多的生物信息学接触， 分子和细胞生物学以及整合药理学的生物统计学。我们的课程可以广阔 从蜂窝网络到器官功能到行为和系统医学。培训将增强他们的 了解对其研究和研究领域特有的药物机制的理解，并使它们能够表征 疾病中新型药物靶标和信号通路。学员和导师都将参加结构化 心理训练。在支持期间，所有学员将有两个专门的实习障碍：一部分 - 时间，长期安排将在乔治敦（例如，监管事务，技术商业化）举行； 第二块将是在当地合作机构（Biotech，政府，基金会）的暑期实习。 这，我们的学员将在发展自己的职业道路上广泛接触可转移的技能 研究能力。我们设定了计划目标，包括（1）在5。5年内实现95％的学位 （2）在我们的学员池中实现代表不足的群体的30％代表，（3）实现 100％的导师和受训者参与正式导师培训，（4）获得四个高影响力出版物 每学员，（5）在学位后的两年内实现了与药物有关的职业的75％职业，（6） 继续扩大我们的实习机会，（7）增加研究生中最佳实践的采用 招生。我们致力于培训下一代药物科学家，以此为基础 乔治敦（Georgetown）在药理学成功方面的长期记录的优势。