Prenatal alcohol/cannabinoid co-exposures and fetal brain development
Prenatal alcohol/cannabinoid co-exposures and fetal brain development
批准号:
10517743
负责人:
Kirill V Larin
金额:
$1.46万
依托单位国家:
美国
项目类别:
财政年份:
2020
资助国家:
美国
项目状态:
未结题
起止时间:
2020-05-01 至 2025-04-30
关键词:
Alcohol abuseAlcoholsAngiographyAreaAwardBehavioralBiological AssayBiophysicsBlood VesselsBlood flowBrainCannabinoidsCellsCerebrovascular CirculationCollaborationsCommunicationComplementData AnalysesDevelopmentDoseDrug abuseEmbryoEnsureEthanolExperimental DesignsExposure toFemaleFluorescenceGoalsGrowthHealthImageImaging TechniquesImaging technologyLaboratoriesLightLong-Term EffectsMentorsMentorshipMicroscopyMultimodal ImagingMusNational Institute on Alcohol Abuse and AlcoholismNeonatalOptical Coherence TomographyOpticsParentsPhysiologicalPhysiologyProcessProtocols documentationPublishingReporterResearchResearch PersonnelResearch Project GrantsStainsTomatoesTrainingUltrasonographyWritingalcohol effectalcohol exposurealcohol researchangiogenesisbasebehavioral outcomebiomedical imagingcareerexperimental studyfetalfluorescence imaginghigh resolution imagingimaging approachin uteroin vivomalemultidisciplinarynerve stem celloffspringoptical imagingparent grantprenatalresearch and developmentresponseskillssynthetic cannabinoidtoolvasculogenesis
中文摘要
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英文摘要
PROJECT SUMMARY
This is an application in response to NIAAA Research Supplements to Promote Diversity in
Health-Related Research. The candidate's research will be within the scope of the parent award:
the utilization of optical noninvasive and high-resolution imaging technology to assess the effects
of ethanol and cannabinoid exposure on fetal brain growth and analyze the changes in the
vasculature supporting brain development. Complementing the approach described in the parent
grant, the candidate will perform additional experiments of embryonic imaging using fluorescence
and ultrasound imaging techniques for corroboration with the ongoing and already published
Optical Coherence Tomography (OCT)-imaged results.
The candidate's training plan includes the development of research, communication, and writing
skills and extensive training in physiology and biophysics of alcohol and drug abuse.
.
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会议论文
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海外基金