TREATMENT OF CHRONIC PTSD SECONDARY TO TRAFFIC ACCIDENTS

描述（改编自申请人摘要）：来自几个 调查表明，创伤后应激障碍（PTSD）可能是一个 在美国最普遍的精神病问题， PTSD病例的比例可能继发于机动车事故 （MVAs）。 迄今为止，已发表的关于该人群治疗的报告 除了一个早期被控制的， 干预试验未能发现短期治疗优于 没有治疗。 (The后一个发现可能是由于相当大的 MVA后前6至9个月的自发缓解率，确定 （在提交本提案的调查人员的工作中）其他受控 对创伤后应激障碍治疗的评估集中在非常慢性的病例上， 越战老兵和强奸受害者。 这些研究人员建议评估一个简短的（十届）多组分 认知行为治疗方案，他们已经试点， 由经验丰富的社区治疗师，相比之下，一个简短的（十 支持性心理治疗和等待名单控制，在一个 对照临床试验，使用105名最近（6至24个月） MVA后），但技术上慢性PTSD或严重的亚综合征PTSD 一次机动车事故。 调查人员将筛选 大约320名机动车辆事故受害者寻求医疗照顾， MVA后超过24个月，以确定和招募105名样本; 这将包括最近（不到6个月）6个月后的重新评估 例 对治疗状况不知情的评估者将评估所有治疗的 治疗后以及3和12次随访时的受试者和等待列表对照 使用CAPS，LIFE和各种心理测试。 轮候册 对照组将接受认知行为治疗后， 重新评估

DESCRIPTION (Adapted from applicant's abstract): Evidence from several surveys indicates that posttraumatic stress disorder (PTSD) may be one of the most widespread psychiatric problems in the USA, and that a sizeable proportion of PTSD cases may arise secondary to motor vehicle accidents (MVAs). To date, the published reports of treatment with this population have been uncontrolled, with the exception of one controlled early intervention trial which failed to find an advantage of brief treatment over no treatment. (The latter finding may be due to a fairly sizeable spontaneous remission rate over the first 6 to 9 months post-MVA, identified in the work of the investigators submitting this proposal.) Other controlled evaluations of treatment of PTSD have focused on very chronic cases such as Vietnam veterans and on rape victims. These investigators propose to evaluate a brief (ten session) multicomponent cognitive behavioral treatment regimen which they have piloted, administered by experienced community-based therapists, in comparison to a brief (ten session) supportive psychotherapy and a waiting list control, in a controlled clinical trial using 105 individuals with recent (6 to 24 months post MVA) but technically chronic PTSD or severe sub-syndromal PTSD secondary to a motor vehicle accident. The investigators will screen approximately 320 MVA victims who sought medical attention and who are less than 24 months post-MVA in order to identify and recruit the sample of 105; this will include reassessment after 6 months for recent (less than 6 month) cases. Assessors, blind to treatment condition, will evaluate all treated subjects and wait list controls at post-treatment and follow-ups of 3 and 12 months using the CAPS, LIFE, and various psychological tests. Waiting list controls will receive the cognitive behavioral treatment after their reassessment.