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MECHANISMS OF HISTAMINE RELEASE

MECHANISMS OF HISTAMINE RELEASE
组胺释放机制
批准号：
2572227
负责人：
R P SIRAGANIAN
金额：
$0.0万
依托单位：
NATIONAL INSTITUTE OF DENTAL & CRANIOFACIAL RESEARCH
依托单位国家：
美国
项目类别：
财政年份：
--
资助国家：
美国
项目状态：
未结题
起止时间：
至
来源：
https://reporter.nih.gov/project-details/2572227
关键词：
antibody receptor basophils biological models biological signal transduction calcium channel histamine release immunoregulation inflammation ionophores leukocyte activation /transformation mast cell neoplastic cell culture for noncancer research phosphorylation protein tyrosine kinase secretion tissue /cell culture

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中文摘要
翻译
肥大细胞和嗜碱性细胞的组胺释放被研究为
英文摘要
Histamine release from mast cells and basophils is being studied as an immunological mechanism involved in inflammation. The activation of these cells by immune cell surface receptors is also a model for signal transduction and cell secretion. Besides cell surface receptors, the cells can be activated by other secretagogues such as the calcium ionophore A23187. The emphasis the last few years has been in understanding the role of protein tyrosine phosphorylations in the signalling. The cultured rat basophilic leukemia cells are used as one of the main models for these studies.
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会议论文
MECHANISMS OF HISTAMINE RELEASE
MECHANISMS OF HISTAMINE RELEASE
ROLE OF ADHESION MOLECULES IN MAST CELL AND BASOPHILS FUNCTION
PROTEIN TYROSINE PHOSPHATASES IN CELLULAR SIGNALING
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