ESTABLISHMENT OF A CHIMPANZEE BREEDING/RESEARCH PROGRAM

生物医学和行为学家认为黑猩猩(潘 狼人)对针对重要人类的调查至关重要 健康问题，因为黑猩猩和人类有共同的进化 免疫系统、基因组成和易感性方面的相似性 病毒病原体，最主要的是艾滋病毒和肝炎病毒。《国家报》 卫生研究院建立了五个中心，由NCRR管理 国家黑猩猩繁育和研究计划(CBRP)，以永续 美国的黑猩猩数量和确保黑猩猩的稳定供应 黑猩猩进行了这项重要的研究。作为五个中心之一 被选中参加CBRP，美国-新伊比利亚研究 NIRC中心(NIRC)现在已经建立了一个富有成效的黑猩猩繁殖者群体 由128只动物组成。NIRC在遗址上有292只黑猩猩 该设施总共容纳了4500名非人类灵长类动物。《长河》 NIRC的任期目标是为以下目标建立的支持 NIH/NCRR关于黑猩猩永久化的研究 通过维持健康的繁殖人口和 确保这一宝贵资源的稳定供应 生物医学和行为研究，并通过分配发行到 研究60%或更多的群体，实现很大程度的财务 自给自足。 NIRC计划的具体目标是：继续成功繁殖 和黑猩猩的维持，以及合适的CBRP后代的问题 使用既定的成本效益管理做法的调查人员； 确保殖民地的健康、福祉和生产力 维护；为了保障相关人员的健康，最大限度地 遏制和控制殖民地，并提供适当的安全； 并继续收集CBRP的详细计算机记录 黑猩猩。此外，该中心正在努力纳入 将遗传数据录入记录系统，建立全面繁育体系 将保持CBRP基因异质性的管理计划 人口。 建议的黑猩猩繁殖方法将继续是我们的 建立了后备种鸡群体与已证明的单一品种的交配体系 男性，以及实施确保基因库多样性的程序。 将尽一切努力让后代与家人在一起 群居，直到他们达到性成熟。人工哺育婴儿将是 避免，除非出现损害婴儿福利的情况或 妈的。在这种情况下，NIRC经过验证的托儿所程序和非人类 灵长类动物管理计划将用于发展 健康的，融入社会的，后代。 该中心已经建立并将继续实施以下使用费： 黑猩猩被发布进行研究。鼓励使用研究，前提是 它与NIRC的优先使用政策和实验一致 经适当的动物护理和使用机构批准的议定书 委员会审议阶段。

Biomedical and behavioral scientists consider the chimpanzee (Pan troglodytes) essential to investigations directed at important human health problems because the chimpanzee and human share evolutionary similarities in immune system, genetic make-up, and susceptibility to viral disease agents, most notably HIV and hepatitis viruses. The National institutes of Health established five centers, managed by the NCRR national chimpanzee breeding and research program (CBRP), to perpetuate the chimpanzee population in the U.S. and to insure the stable supply o chimpanzees for this essential research. As one of the five centers selected to participate in the CBRP, the U.S.L. - New Iberia Research Center (NIRC) has established a productive chimpanzee breeder colony, now consisting of 128 animals. NIRC has 292 chimpanzees on sites and the facility houses a total population of 4500 non-human primates. The long term objective of NIRC is the support the goals established for chimpanzees by the NIH/NCRR in regard to perpetuation of the chimpanzee population in the U.S. by maintenance of a healthy breeding population and to insure the stable supply of this valuable resource for essential biomedical and behavioral research and, by allocating for issue to research 60% or more of the colony, achieve great a measure of financial self-sufficiency. Specific aims of NIRC's program are: to continue the successful breeding and maintenance of chimpanzees, and the issue of suitable CBRP progeny to investigators using established cost-effective management practices; to insure that the health, well-being, and productivity of the colony are maintained; to safeguard the health of personnel involved, maximize the containment and control of the colony, and provide appropriate security; and to continue to amass detailed computerized records of CBRP chimpanzees. In addition, the Center is working toward the inclusion of genetic data into the record system to establish a comprehensive breeder management plan that will maintain genetic heterogeneity of the CBRP population. The methods proposed for chimpanzee breeding will continue to be our established mating system of harem breeder groups with a single proven male, and the implementation of procedures to insure gene pool diversity. Every effort will be made to allow offspring to remain with the family group until they attain sexual maturity. Hand rearing of infants will be avoid unless conditions occur that compromise the welfare of the infant or dam. In such cases, NIRC's proven nursery care procedures and non-human primate management plan will be used to allow for the development of healthy, socially integrated, offspring. The Center has established, and will continue to implement, a user fee for chimpanzees issued to research. Research use is encouraged, provide that it is consistent with NIRC's prioritized use policy and the experimental protocol approved by the appropriate institutional animal care and use committee.