TOBACCO: PRENATAL EFFECTS AND ADOLESCENT USE

描述：(申请人摘要) 孕产妇保健实践和儿童发展项目是一个有前景的项目 孕期烟草暴露对755仔鼠影响的研究 女人。我们已经确定了产前烟草暴露的重大影响。 子代中枢神经系统发育的研究进展 犯罪行为和同伴问题。在10岁的时候，孩子们 已经开始用烟草和其他物质进行试验。这些孩子 他们越抑郁和焦虑，注意力问题就越多， 攻击性和犯罪行为。 我们将评估心理和身体发展的长期影响， 气质，心理状态，活动水平，学习成绩， 行为问题、环境和产前暴露 青少年在14岁和16岁时的物质使用情况及其对儿童发育的影响 在14岁到16岁之间使用烟草。之前没有研究能够 探索青少年烟草使用的预测因素，从出生到 青春期。 该队列是从低收入女性中挑选出来的一般人群样本 一家产前诊所。一半的女性是高加索人，一半是非裔美国人。 我们在产前4个月和4个月对这些母亲和她们的孩子进行了评估 7、分娩，8个月和18个月，3年、6年和10年。我们有一个不同寻常的 10年随访率达91%。

DESCRIPTION: (Applicant's Abstract) The Maternal Health Practices and Child Development Project is a prospective study of the effects of prenatal tobacco exposure on the offspring of 755 women. We have identified significant effects of prenatal tobacco exposure on the offsprings' development of the central nervous system and on delinquent behavior and peer problems. At 10 years of age, the children have begun to experiment with tobacco and other substances. These children were more depressed and anxious, they had more attention problems, aggression, and delinquency. We will assess the long-term effects of mental and physical development, temperament, psychological status, activity levels, academic performance, behavior problems, the environment, and prenatal exposure on the adolescents' substance use at age 14 and 16 and on the development of tobacco use between the ages of 14 and 16. No prior study has been able to explore the predictors of adolescent tobacco use across time, from birth to adolescence. The cohort is a general population sample of low income women selected from a prenatal clinic. Half the women are Caucasian, half are African-American. We have assessed these mothers and their children at prenatal months 4 and 7, delivery, 8 and 18 months, 3, 6, and 10 years. We have an exceptional follow-up rate of 91% at 10 years.